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Anti-Helicobacter pylori Potential of Three Edible Plants Known as Quelites in Mexico
Erika Gomez-Chang,Guadalupe Vanessa Uribe-Estanislao,Maricruz Martinez-Martinez,Amanda Galvez-Mariscal,Irma Romero 한국식품영양과학회 2018 Journal of medicinal food Vol.21 No.11
“Quelites” are edible plants that are part of the traditional agro-ecosystems in Mexico. These plants, despite their already known nutritional properties, are now considered neglected and underutilized species. With the objective of promoting their reinsertion in the markets and mainly, in daily diets, efforts have been made to study them from multidisciplinary approaches to demonstrate their beneficial properties. To generate evidence of an added health-promoting value that would encourage quelites consumption, in the present work, the anti-Helicobacter pylori activity of three representative quelite species, Anoda cristata (Alache), Cnidoscolus aconitifolius (Chaya), and Crotalaria pumila (Chepil), was tested. H. pylori is considered the etiological agent of gastritis, ulcer, and gastric cancer, and represents a public health problem in Mexico and worldwide. Aqueous (AQ) and dichloromethane–methanol (DM) extracts were obtained from the three species of quelites to investigate their effect on H. pylori growth and on two of its colonization factors (adherence and urease activity). DM extracts from Chaya, Chepil, and Alache exert the best inhibitory effect on bacterial growth, with minimum inhibitory concentrations of 62.5, 125, and 250 μg/mL, respectively. AQ and DM extracts inhibit bacterial adhesion by 30% to 50%. None of them has an effect on urease activity. The two flavonoids present in A. cristata, acacetin and diosmetin, inhibit H. pylori growth by ∼90% with 3.9 μg/mL. These results provide new information about the anti-H. pylori potential of three edible quelites, and give an added value, since their routine consumption may impact on the prevention and/or control of H. pylori-associated diseases.
Salient and Relevant Colors in Digital Images of Paintings
Juan Luis Nieves,Luis Gomez-Robledo,Javier Romero 한국색채학회 2017 AIC 2017 Jeju Vol.2017 No.10
The painters in their works not only try to faithfully shape a scene, but to submit this representation to the painter`s mind, according to his training and aesthetic taste. We find of great interest to characterize what we can understand as relevant information in a painting. Techniques for determining "salient" information in an image have recently been developed. It is a question of determining in an image the objects or areas in which an observer focus its attention. With these techniques we can establish which the fundamental colors of a painting are. We have applied the Graph-Based Visual Saliency algorithm (GBVS) to a set of digital images of six painters (Titian, El Greco, Rubens, Velázquez, Rembrandt and Vermeer). We have obtained the number of salient colors in each image after applying a method for counting discernible colors. We have taken a step further by applying thresholds at different levels to determine which the really relevant colors in a scene are, so that we approach the subjective judgments that would give an observer of the colors that stand out in a certain painting. When we evaluate the percentage of reduction of the number of discernible colors in the salient areas, this parameter is less for Rembrandt, Velázquez and Vermeer than for Titian, El Greco and Rubens. This can show a difference in the use of colors with the period that is with the evolution from the renaissance to baroque style. However, when we have evaluated the relevant colors, there is a slight variation in the average values obtained, 15 to 20. We could conclude that the number of relevant colors in the paintings do not change so significantly as the total number of discernible colors according to authors and according to paintings.
Neural Transdifferentiation: MAPTau Gene Expression in Breast Cancer Cells
Lara-Padilla, E,Miliar-Garcia, A,Gomez-Lopez, M,Romero-Morelos, P,Bazan-Mendez, CI,Alfaro-Rodriguez, A,Anaya-Ruiz, M,Callender, K,Carlos, A,Bandala, C Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.4
Background: In tumor cells, aberrant differentiation programs have been described. Several neuronal proteins have been found associated with morphological neuronal-glial changes in breast cancer (BCa). These neuronal proteins have been related to mechanisms that are involved in carcinogenesis; however, this regulation is not well understood. Microtubule-associated protein-tau (MAP-Tau) has been describing in BCa but not its variants. This finding could partly explain the neuronal-glial morphology of BCa cells. Our aim was to determine mRNA expression of MAP-tau variants 2, 4 and 6 in breast cancer cell lines. Materials and Methods: Cultured cell lines MCF-10A, MDA-MB-231, SKBR3 and T47D were observed under phase-contrast microscopy for neural morphology and analyzed for gene expression of MAP-Tau transcript variants 2, 4 and 6 by real-time PCR. Results: Regarding morphology like neural/glial cells, T47D line shown more cells with these features than MDA-MB-231 and SKBR. In another hand, we found much greater mRNA expression of MAP-Tau transcript variants 2, and to a lesser extent 4 and 6, in T47D cells than the other lines. In conclusion, regulation of MAP-Tau could bring about changes in cytoskeleton, cell morphology and motility; these findings cast further light on neuronal transdifferentiation in BCa.
Jorge Rios-Zermeno,Leoncio Alberto Tovar-Romero,Gerardo Cano-Velazquez,Ricardo Marian-Magana,Marcos Sangrador-Deitos,Juan Luis Gomez-Amador 대한뇌혈관외과학회 2023 Journal of Cerebrovascular and Endovascular Neuros Vol.25 No.3
Intracranial aneurysms arise in 1-2% of the population and usually present as hemorrhagic strokes. Spontaneous thrombosis of a ruptured intracranial aneurysm occurs in 1-3% and most commonly in giant aneurysms, with complete thrombosis in just 13-20% of the cases. Thrombosis of smaller aneurysms is rare. Here we present a case of a patient who presented with a ruptured intracranial aneurysm that subsequently thrombosed, discovering a neighboring de-novo aneurysm during follow-up. We hypothesized that after thrombosis, the hemodynamic characteristics that contributed to the formation of the first aneurysm were replicated.
Towards flexible solid-state supercapacitors for smart and wearable electronics
Dubal, Deepak P.,Chodankar, Nilesh R.,Kim, Do-Heyoung,Gomez-Romero, Pedro The Royal Society of Chemistry 2018 Chemical Society reviews Vol.47 No.6
<P>Flexible solid-state supercapacitors (FSSCs) are frontrunners in energy storage device technology and have attracted extensive attention owing to recent significant breakthroughs in modern wearable electronics. In this study, we review the state-of-the-art advancements in FSSCs to provide new insights on mechanisms, emerging electrode materials, flexible gel electrolytes and novel cell designs. The review begins with a brief introduction on the fundamental understanding of charge storage mechanisms based on the structural properties of electrode materials. The next sections briefly summarise the latest progress in flexible electrodes (<I>i.e.</I>, freestanding and substrate-supported, including textile, paper, metal foil/wire and polymer-based substrates) and flexible gel electrolytes (<I>i.e.</I>, aqueous, organic, ionic liquids and redox-active gels). Subsequently, a comprehensive summary of FSSC cell designs introduces some emerging electrode materials, including MXenes, metal nitrides, metal-organic frameworks (MOFs), polyoxometalates (POMs) and black phosphorus. Some potential practical applications, such as the development of piezoelectric, photo-, shape-memory, self-healing, electrochromic and integrated sensor-supercapacitors are also discussed. The final section highlights current challenges and future perspectives on research in this thriving field.</P>