SYSTEM ANALYSIS OF DISASTER PREVENTION DESIGN CRITERIA FOR COASTAL AND ESTUARY CITIES

De Fu Liu,Sheng Dong,Shu Qing Wang,Chao Wang 한국해안해양공학회 1999 학술강연회 발표논문초록집 Vol.2 No.1

In China, estuary and coastal cities are mostly regional economic development center. The disasters by combined effect of upper reaches flood, storm surge and Typhoon waves are the primary obstacle to economic development of cities. So how to make economic and risk system analysis for flood-storm surge-wave disaster, economic loss and flood-storm surge control measures plays a very important role in the sustainable development of coastal cities. There are three types of coastal cities for consideration. First type city like Tianjin, the most significant damage is from upper reaches flood of a river. The effect of storm surge is negligible, because in the estuaries of river Haihe catchment basin are built tidal barrages. This paper presents a Grey Markov Model (GMM) to forecast flood peak level. GMM combines Grey system and Markov theory to present a high-precision model. Results of forecasted flood peak levels are closed to the measured data. Establish a synthetical model for economic assessment, risk analysis and flood-control benefit. As new contribution, a stochastic simulation technique is used to compute risk probability. In the same time, take into account the effect of correlation between variables on risk probability. Second type city like Shanghai, where sometimes the combined effect of flood peak of river, storm surge from sea is most severe disaster for city damage. 1000 yrs. return period water level of Huangpu river is used as traditional design criteria. Simulated combined water level of flood peak, storm surge and maximum astronomical tide level from sea side with 400 yrs. return period is close to 1000 yrs. design water level by traditional method. For third type city, like Qingdao, where combined effect of maximum astronomical tide, storm surge and waves brought most significant damage to Qingdao. Using stochastic simulation technique, different combinations of storm surge, waves with 1%,2% joint probability level are simulated for disaster prevention.

NANOTOXICITY OF MULTIWALL CARBON NANOTUBES TO A549 CELLS IN VITRO

FU-DE WANG,Ying Tang,Yong Ji Yang,CHAN JIN,HUA ZHANG,HAO LIANG 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2014 NANO Vol.9 No.2

Multiwall carbon nanotubes (MWCNTs) have been widely applied in many ¯elds due to theexcellent physical and chemical properties. As the production and applications of nanotubesexpand, public concern about their potential risks to human health has also raised. Cytotoxicityof MWCNTs was evaluated in this study using a cultured human epithelial cell line A549. Uptakeof MWCNTs by cultured A549 cells was observed by TEM imaging. Dose-dependent decrease ofcell viability showed the cytotoxicity of MWCNTs. Signi¯cant reactive oxygen species (ROS)generation and GSH depletion which reduced the cellular antioxidant level could be the majorfactor of cytotoxicity induced by MWCNTs. MWCNTs seemed to trigger the activation of cellautophagy with the intracellular ATG16L1 level increase as a defense mechanism.

EFFECTS OF CARBON NANOTUBES ON RAT LIVER AND BRAIN

FU-DE WANG,CHAN JIN,LING-LING CAO,HAO LIANG,CHUN-WANG MA 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2014 NANO Vol.9 No.7

Carbon nanotubes (CNTs) have been widely applied in various ¯elds due to excellent physicaland chemical properties. As production and applications of nanotubes expand, public concernabout their potential risks to human health has also risen. In the present study, the e®ects ofCNTs on rat liver and brain by single intratracheal instillation were detected. CNTs [eithersingle-walled carbon nanotubes (SWCNTs) or multi-walled carbon nanotubes (MWCNTs)] couldbe seen in the lung and liver indicating the transfer of CNTs by blood stream. CNTs could induceoxidative stress in liver with elevated Malondialdehyde (MDA) level and degressive GSH level,superoxide dismutase (SOD) and CAT activity. To brain, maybe due to the blood brain barrierand the increased SOD and CAT activity, serious oxidative stress of brain did not occur.

Microwave Ablation Treatment of Liver Cancer with a 2,450-MHz Cooled-shaft Antenna: Pilot Study on Safety and Efficacy

Jiao, De-Chao,Zhou, Qi,Han, Xin-Wei,Wang, Ya-Feng,Wu, Gang,Ren, Jian-Zhuang,Wang, Yan-Li,Ding, Peng-Xu,Ma, Ji,Fu, Ming-Ti Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.2

To evaluate efficacy of microwave ablation in a primary clinical study, sixty patients (44 men, 16 women; mean age 53 years) with 96, 1-8 cm (mean $3.20{\pm}0.17$ cm) liver cancers were treated with 2,450-MHz internally cooled-shaft antenna. Complete ablation (CA) and local tumor progression (LTP) rates as well as complications were determined. CA rates in small (< 3.0 cm), intermediate (3.1-5.0 cm) and large (5.1-8.0 cm) liver cancers were 96.4% (54/56), 92.3% (24/26) and 78.6% (11/14), respectively. During a mean follow-up period of $17.17{\pm}6.52$ months, LTP occurred in five (5.21%) treated cases. There was no significant difference in the CA and LTP rates between the HCC and liver metastasis patient subgroups (P<0.05). Microwave ablation provides a reliable, efficient, and safe technique to perform hepatic tumor ablation.

Arm Exoskeleton Rehabilitation Robot with Assistive System for Patient after Stroke

Guan De Lee,Wei-Wen Wang,Kai-Wen Lee,Sheng-Yen Lin,Li-Chen Fu,Jin-Shin Lai,Wen-Shiang Chen,Jer-Junn Luh 제어로봇시스템학회 2012 제어로봇시스템학회 국제학술대회 논문집 Vol.2012 No.10

Exercise dosage is proven to be an important factor in the physical treatment. Robot assistive approach can improve the rehabilitation quality and evaluate patient’s recovery quantitatively. This paper presents kinematic structure, assistive control system, and integrated F/T sensor for an upper limb rehabilitation robot. By using the human arm dynamic, there are three rehabilitation modes presented in this paper: active mode, assistive mode, and passive mode. In assistive mode, we have two strategies to implement it. One is to amplify interactive torque, and the other is to apply assist-as-needed concept. The goal of this mode is to assist patients to finish motion tasks. The rehabilitation robot under investigation has 7 degree of freedom (DOF) actuated by DC motors, which are programmed to drive the robot arm in the 3D space. To validate our control design, some realistic experiments are conducted and its satisfactory performance is demonstrated. This work is approved clinical testing by the Department of Health, Executive Yuan, R.O.C. So far, we are demonstrating the effect of our controller.

Electrophysiological and behavioral responses of Tenebrio molitor L. to fourteen kinds of plant volatiles

Yan-chen Wang,Peng Li, De-fu Chi 한국응용곤충학회 2016 Journal of Asia-Pacific Entomology Vol.19 No.2

To utilize plant volatiles in themonitoring and biological control of Tenebrio molitor L., electroantennogramography (EAG), Y-tube olfactometry and wind tunnel bioassays were conducted to test the electrophysiological and behavioral responses of T. molitor to nine individual volatiles and five essential oils (compounded volatiles). The aim of this studywas to select effective plant compounds that could be used in the development of semi-chemical based push– pullmethods for the control of this harmful stored product pest. T. molitor displayed strong EAG responses to cis-3- hexenol, isoeugenol, α-pinene, turpentine oil, eucalyptus oil and peppermint essential oil. Y-tube olfactometry assays indicated that peppermint essential oil showed greater luring effects on adult T. molitor than the control. Cis- 3-hexenol elicited strong repellent effects on adult T. molitor, and wind tunnel assays indicated that cis-3-hexenol showed strong repellent effects on adult T. molitor. Peppermint essential oil showed greater luring effects than the control. These results provide a basis to further the development of T. molitor luring and repellent agents.

Pathological Impact on the Phyllosphere Microbiota of Artemisia argyi by Haze

( Yu-zhu Zhang ),( De-yu Jiang ),( Chi Zhang ),( Kun Yang ),( Huai-fu Wang ),( Xiu-wen Xia ),( Wei-jun Ding ) 한국미생물생명공학회(구 한국산업미생물학회) 2021 Journal of microbiology and biotechnology Vol.31 No.4

The pathological impact of haze upon the phyllosphere microbiota awaits investigation. A moderate degree of haze environment and a clean control were selected in Chengdu, China. Artemisia argyi, a ubiquitously distributed and extensively applied Chinese herb, was also chosen for experiment. Total genome DNA was extracted from leaf samples, and for metagenome sequencing, an Illumina HiSeq 2500 platform was applied. The results showed that the gene numbers of phyllosphere microbiota derived from haze leaves were lower than those of the clean control. The phyllosphere microbiota derived from both haze and clean groups shared the same top ten phyla; the abundances of Proteobacteria, Actinomycetes and Anorthococcuso of the haze group were substantially increased, while Ascomycetes and Basidiomycetes decreased. At the genus level, the abundances of Nocardia, Paracoccus, Marmoricola and Knoelia from haze leaves were markedly increased, while the yeasts were statistically decreased. KEGG retrieval demonstrated that the functional genes were most annotated to metabolism. An interesting find of this work is that the phyllosphere microbiota responsible for the synthesis of primary and secondary metabolites in A. argyi were significantly increased under a haze environment. Relatively enriched genes annotated by eggNOG belong to replication, recombination and repair, and genes classified into the glycoside hydrolase and glycosyltransferase enzymes were significantly increased. In summary, we found that both structure and function of phyllosphere microbiota are globally impacted by haze, while primary and secondary metabolites responsible for haze tolerance were considerably increased. These results suggest an adaptive strategy of plants for tolerating and confronting haze damage.

Improving thermal shock and ablation resistance of high thermal conductivity carbon/carbon composites by introducing carbon nanotubes

Liu Xue-Song,Fu Qian-Gang,Wang Han-Hui,Tong Ming-De,Zhang Jia-Ping,Song Qiang 한국탄소학회 2020 Carbon Letters Vol.30 No.6

In order to improve the thermal shock and ablation resistance of high thermal conductivity carbon/carbon composites, carbon nanotubes (CNTs) were introduced by electrophoretic deposition. After modifcation, the fexural strength of the composites increases by 53.0% due to the greatly strengthened interfaces. During thermal shock between 1100 °C and room temperature for 30 times, the strength continues to increase, attributed to the weakened interfaces in favor of fber and CNT pull-out. By introducing CNTs at interfaces, thermal conductivity of the composites along the fber axial direction decreases and that along the fber radial direction increases. As the thermal shock process prolongs, since the carbon structure integrity of CNT and matrix in the modifed composites is improved, the conductivity increases whatever the orientation is, until the thermal stress causes too many defects. As for the anti-ablation performance, the mass ablation rates of the CNT-modifed composites with fbers parallel to and vertical to the fame decrease by 69.6% and 43.9% respectively, and the diference in the mass ablation rate related with fber orientations becomes much less. Such performance improvement could be ascribed to the reduced oxidative damage and the enhanced interfaces.

Study on molten salt oxidation process of simulated Co doped cation exchange resins

Yun Xue,Yue-Lin Wang,Yu Li,Wen-Da Xu,Fu-Qiu Ma,Yang-Hai Zheng,Qing-Guo Zhang,Zhi Zhang,Mi-lin Zhang,Yong-De Yan 한국공업화학회 2023 Journal of Industrial and Engineering Chemistry Vol.126 No.-

Cation exchange resins (CERs) are widely applied to purify waste liquids generated during the operationof nuclear reactors. The radioactive nuclides 60Co and 58Co are important corrosion activation products inreactor cooling water. In this study, the simulated Co doped CERs were oxidized with ternary carbonate. According to the thermogravimetric analysis (TG), the decomposition of Co doped CERs includes threeprocesses: 1. Elimination of the osmotic water; 2. Pyrolysis of sulfonic acid group; 3. Destruction of styrene–divinylbenzene copolymer. The X-Ray Diffraction (XRD) patterns indicate that sulfur mainly exists inthe form of sulfate in waste salt. The Co2+ undergoes the path of CoS2 ? Co3O4 with the increase of temperatureand the transition point is 650 C. Combined with Fourier Transform Infrared Spectrometer (FTIR)spectra and X-ray Photoelectron Spectroscopy (XPS) analysis, sulfonic acid groups begin to decomposeat 350 C. During the molten salt oxidation process, most of the sulfur in sulfonic acid groups is entrappedby carbonate as the form of sulfate, and a little of which remains as sulfone group, sulfoxide group andsulfur bridge in residue. When the resins are oxidized at 800 C, the retention rate of Co2+ is 97.3%, indicatingthat the molten salt oxidation can effectively remain Co2+ and convert it into a more stablesubstance.

Presence of Tumour-infiltrating FOXP3⁺ Lymphocytes Correlates with Immature Tumour Angiogenesis in Renal Cell Carcinomas

Zhan, Hai-Lun,Gao, Xin,Zhou, Xiang-Fu,Pu, Xiao-Yong,Wang, De-Juan Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.3

Background: $FOXP3^+$ regulatory T cells (Tregs) inhibit effector T cell functions and are implicated in tumour progression. However, together with microvessel density (MVD) they remain controversial prognostic predictors for renal cell carcinoma (RCC), and potential associations have yet to be determined. The objective of this study was to determine the prognostic significance of Tregs and MVD and their potential relationship in RCCs. Design: Paraffin-embedded tissues from 62 RCC patients were analysed using immunohistochemistry to detect $FOXP3^+$ lymphocytes, and double immunohistochemistry to detect different microvessel types in the tumour interior, rim and normal kidney tissue, and their correlation with clinicopathological characteristics. Survival analysis was also performed. Results: The presence of $FOXP3^+$ cells in the tumour interior or the rim showed no correlation with death from RCC and other pathological characteristics. Negative correlations were noted between the immature MVD in the tumour interior or the rim and tumour size, tumour stage and overall survival; however, there was no correlation with the nuclear grade or pathological type. A positive correlation between $FOXP3^+$ Tregs and immature MVD (r=0.363, P=0.014) and mature MVD (r=0.383, P=0.009) was confirmed in the tumour interior. However, there was no correlation between $FOXP3^+$ Tregs and mature MVD (r=0.281, P=0.076) or immature MVD (r=0.064, P=0.692) in the tumour rim. Conclusions: In this study, a positive correlation between the presence of $FOXP3^+$ Tregs and immature and mature MVD in RCC was confirmed, which suggests a link between suppression of immunity, tumour angiogenesis and poor prognosis.