Sensitization of Children to Storage Mites in Kutahya, Turkey

Cihangir Akdemir,Erdogan Soyucen 대한기생충학열대의학회 2009 The Korean Journal of Parasitology Vol.47 No.4

Relation of Nickel Allergy with in-Stent Restenosis in Patients Treated with Cobalt Chromium Stents

( Cihangir Aliagaoglu ),( Hakan Turan ),( Ismail Erden ),( Hulya Albayrak ),( Hakan Ozhan ),( Cengiz Basar ),( Zehra Gurlevik ),( Aysegul Alcelik ) 대한피부과학회 2012 Annals of Dermatology Vol.24 No.4

Background: In-stent restenosis (ISR) is the major limitation of percutaneous coronary stenting procedure. The elements like nickel, chromate and molybdenum are known to cause contact allergy. Hypersensitivity reaction, against these metal ions, may be one of the reasons of ISR. Cobalt chromium coronary stents, which are increasingly being used in percutaneous coronary interventions, have more nickel amount than the stainless steel stents. Objective: We aimed to investigate the association between nickel hypersensitivity reaction and ISR in patients treated with cobalt chromium coronary stents. Methods: Epicutaneous patch tests for nickel were applied to 31 patients who had undergone elective cobalt chromium coronary stent implantation and had ISR in control angiogram. Thirty patients, without ISR, were included as the control group. Patch test results and other clinical variables were compared. Results: There was no statistically significant difference of the mean age, sex, body mass index, rate of hypercholesterolemia, diabetes, hypertension and smoking between the patients with and without ISR. All other lesion characteristics were similar in the 2 groups. According to the patch test results, 7 patients had nickel contact allergy. All of these patients were in the ISR group, which was statistically significant (p<0.006). Conclusion: Patients treated with cobalt chromium coronary stents and had ISR were found to have significantly more nickel allergy than the control group. Nickel allergy may play role in restenosis pathophysiology. (Ann Dermatol 24(4) 426∼429, 2012)

Outcome of the patients with chronic mesh infection following open inguinal hernia repair

Cihangir Akyol,Firat Kocaay,Erkinbek Orozakunov,Volkan Genc,Ilknur Kepenekci Bayram,Atil Cakmak,Semih Baskan,Ercument Kuterdem 대한외과학회 2013 Annals of Surgical Treatment and Research(ASRT) Vol.84 No.5

Purpose: Hernia repairs are the most common elective abdominal wall procedures performed by general surgeons. The use of a mesh has become the standard for hernia repair surgery. Herein, we discuss a management strategy for chronic mesh infections following open inguinal hernia repair with onlay prosthetic mesh. Methods: In this study, 15 patients with chronic mesh infections following open inguinal hernia repairs were included. The medical records of these patients were retrospectively reviewed and information regarding presentation, type of previous hernia repair, type of mesh, operative findings and bacteriological examination results were obtained. In all cases, the infected mesh was removed completely and the patients were treated with antibiotic regimens and local wound care. Results: Fifteen mesh removals due to chronic infection were performed between January 2000 and March 2012. The mean interval of hernia repair to mesh removal was 49 months. All patients were followed up for a median period of 62 months (range, 16 to 115 months). In all patients, the infections were resolved successfully and none were persistent or recurrent. However, one patient developed recurrent hernia and one developed nerve injury. Conclusion: Chronic mesh infection following hernia repair mandates removal of the infected mesh, which rarely results in hernia recurrence.

ON COMPATIBLE MAPPINGS OF TYPE (I) AND (II) IN INTUITIONISTIC FUZZY METRIC SPACES

Alaca, Cihangir,Altun, Ishak,Turkoglu, Duran Korean Mathematical Society 2008 대한수학회논문집 Vol.23 No.3

In this paper, we give some new definitions of compatible mappings in intuitionistic fuzzy metric spaces and we prove a common fixed point theorem for four mappings under the condition of compatible mappings of type (I) and of type (II) in complete intuitionistic fuzzy metric spaces.

ON FIXED POINT THEOREMS IN INTUITIONISTIC FUZZY METRIC SPACES

Alaca, Cihangir Korean Mathematical Society 2009 대한수학회논문집 Vol.24 No.4

In this paper, we give some new fixed point theorems for contractive type mappings in intuitionistic fuzzy metric spaces. We improve and generalize the well-known fixed point theorems of Banach [4] and Edelstein [8] in intuitionistic fuzzy metric spaces. Our main results are intuitionistic fuzzy version of Fang's results [10]. Further, we obtain some applications to validate our main results to product spaces.

Absence of a Sphenoid Wing in Neurofibromatosis Type 1 Disease: Imaging with Multidetector Computed Tomography

Omer Onbas,Cihangir Aliagaoglu,Cagatay Calikoglu,Mecit Kantarci,Mustafa Atasoy,Fatih Alper 대한영상의학회 2006 Korean Journal of Radiology Vol.7 No.1

Neurofibromatosis type 1 disease is characterized by pigmented cutaneous lesions and generalized tumors of a neural crest origin and it may affect all the systems of the human body. Sphenoid dysplasia is one of the characteristics of this syndrome and it occurs in 5-10% of the cases; further, abnormalities of the sphenoid wings are often considered pathognomonic. However, complete agenesis of a sphenoid wing is very rare. We report here on an unusual case of neurofibromatosis type 1 disease with the associated absence of a sphenoid wing that was diagnosed by using multidetector computed tomography.

Transient Distal Penile Corporoglanular Shunt as an Adjunct to Aspiration and Irrigation Procedures in the Treatment of Early Ischemic Priapism

Onder Canguven,Cihangir Çetinel,Rahim Horuz,Fatih Tarhan,Bilal Hamarat,Cemal Goktas 대한비뇨의학회 2013 Investigative and Clinical Urology Vol.54 No.6

Purpose: Ischemic priapism, a compartment syndrome, requires urgent treatment in order to nourish the corpora cavernosa. As the first step, aspiration of blood and irrigation of the cavernosal bodies is performed to prevent fibrotic activity and secure erectile capability. During aspiration, there are risks of cardiovascular side effects of adrenergic agonists. We aimed to evaluate a transient distal penile corporoglanular shunt technique in place of aspiration and irrigation techniques for treatment of early ischemic priapism. Materials and Methods: A transient distal penile shunt was applied to 15 patients with early ischemic priapism between January 2011 and May 2012. Priapism duration, history,causes, pain, and any prior management of priapism were assessed in all patients. A complete blood count and penile Doppler ultrasonography were performed, which showed attenuated blood flow in the cavernosal artery. A sterile closed system blood collection set, which has two needles and tubing, was used for the transient distal penile shunt. Results: Ten of 15 patients with early ischemic priapism were successfully treated with this transient shunt technique. No additional procedures were needed after the resolution of rigidity in the 10 successfully treated patients. Conclusions: The transient nature of this technique is an advantage over aspiration and irrigation in the treatment of early ischemic priapism. Our results indicate that the technique can be offered for patients with an ischemic priapism episode of no more than 7 hours.

Value of Sentinel Lymph Node Biopsy in Breast Cancer Patients with Previous Excisional Biopsy

Gokhan Coskun,Lutfi Dogan,Niyazi Karaman,Cihangir Ozaslan,Can Atalay 한국유방암학회 2012 Journal of breast cancer Vol.15 No.1

Purpose: Sentinel lymph node biopsy (SLNB) in breast cancer patients with clinically negative axilla will ensure axillary dissection only for cases with lymph node metastasis and provide information about pathologic staging as accurate as the axillary dissection. It was shown that SLNB could be successfully performed regardless of the type of biopsy. The aim of this study was to investigate the feasibility of SLNB after excisional biopsy. Methods:One hundred patients diagnosed with excisional biopsy or guide wire-localization and operated on with SLNB between February 2007 and March 2009 were retrospectively analyzed. SLNB was performed with 10 cc of 1% methylene blue alone or both methylene blue and 1 mCi of Tc-99m nanocolloid combination. Age, tumor localization and size, length of the biopsy incision, size of the biopsy specimen, multifocality, lymphovascular invasion, tumor grade, staining with methylene blue, localization, number and metastatic status of the lymph nodes stained, and success rate with a gamma probe were evaluated. Results: Sentinel lymph node (SLN) could not be identified in 9 (16.9%) of patients in the methylene blue group (n=53). In the combination group (n=47), SLN could not be identified in one patient. Of 32 patients with negative SLNB, metastatic involvement was found to be present in 5 patients after axillary lymph node dissection (false negatives). The average numbers of SLNs found in the methylene blue group and combination group were 1.4 and 1.6, respectively. SLN detection and false negative rates in the methylene blue group were 83% and 15.7%, respectively. The rates for the combination group were 98% and 6.4%, respectively. None of the parameters related to patient, tumor or process were found to affect detection rates of SLN. Conclusion: Only SLNB using a combination method is a safe and reliable technique for breast cancer patients diagnosed with excisional biopsy.

Processing and properties of nano-hBN-added glass/ceramic composites for low-temperature co-fired ceramic applications

Bilaç Oğuzhan,Dursun Gülsüm Meryem,Duran Cihangir 한국세라믹학회 2022 한국세라믹학회지 Vol.59 No.3

LTCC applications require densification at temperatures lower than 950 °C to allow co-firing with metal electrodes, lower dielectric constant to increase signal transmission speed, a thermal expansion coefficient matched to Si for reliability and higher thermal conductivity to dissipate heat. For this purpose, (SiO2–Al2O3–CaO)-based glass (50–60 wt%)/ceramic (Al2O3 or mullite) composites with nano-hBN (0–10 wt%) addition were investigated. Al2O3 was replaced by mullite to decrease dielectric constant and to match thermal expansion coefficient to Si, and hBN was incorporated to increase thermal conduc- tivity and to decrease dielectric constant. Densification at temperatures ≤ 900 °C was easily achieved for all compositions due to viscous sintering of the glass matrix. hBN did not react chemically with crystalline and amorphous phases, which effectively decreased dielectric constant and increased thermal conductivity. Hence, both mullite and nano-hBN strongly improved dielectric and thermal properties required for the LTCC applications. Dense mullite/glass (55 wt%) base composite with 10 wt% hBN addition was successfully engineered and had comparable dielectric and thermal properties (i.e., 2.3 gcm−3 after sintering at 900 °C, dielectric constant (loss) = 5.13 (0.003) at 5 MHz, thermal conductivity = 1.91 Wm−1 K−1 at 25 °C, and thermal expansion coefficient for the base composite = 4.75 ppm°C−1) with respect to the commercial LTCC products.

Comparison of Outcomes of Standard and Oncoplastic Breast-Conserving Surgery

Mehmet ali Gulcelik,Lutfi Dogan,Murat Yuksel,Mithat Camlibel,Cihangir Ozaslan,Erhan Reis 한국유방암학회 2013 Journal of breast cancer Vol.16 No.2

Purpose: The aim of this study is to determine and to compare the oncological outcomes of bilateral reduction mammoplasty to standard breast-conserving surgery for breast cancer. Methods: One hundred sixty-two patients who received a quadrantectomy because of breast cancer (group 1) and 106 breast cancer patients with macromastia who underwent breast-conserving surgery via bilateral reduction mammoplasty (group 2) between 2003 and 2010 were enrolled in this study. Results: The mean follow-up time was 37 months for group 1 and 33 months for group 2. Surgical margins were wider than 2 mm in 82.7% and 10 mm in 76.5% of the patients in group 1. Eleven percent of patients had positive surgical margins in this group. When compared to group 2, the rates were 89%, 84%, and 8.4%, respectively. Three patients (1.8%) in group 1 and one patient (0.9%) in group 2 had local recurrence of the disease and received a mastectomy. No statistical significances were noted for either local recurrence or overall survival between the two groups. Conclusion: Bilateral reduction mammoplasty has some advantages as compared to the standard conventional breast-conserving surgery techniques without having any unfavorable effects on surgical margin confidence, local recurrence, and survival rates.