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지역 특성화 방안으로서의 디자인 가치와 역할에 관한 연구
김병욱,김남훈 한국패키지디자인학회 2002 상품문화디자인학연구 Vol.11 No.-
Industrialization and Urbanization have given rise to ill effects in areas such as standardization and simplification. As a result, each area has developed abnormally losing its own uniqueness. And the values of design have been changing as the main source of design changing. Now is the Information age. The key words of design are culture. So during globalization and localization in country, the diverse economic cultural activities adopting the area's uniqueness are the starting point for development and widening its identity. Excavating and developing local cultural industries are urgent considering the importance of economic profits not having environmental problems. But cultural design can solve this conflict. This study will propose good design cultural city model that has economic and cultural value by design. Factors identifying an area's characteristics may be classified as formation works of urban identity, landscape design, cultural industry, developing local areas, etc. This study was a concrete approach the compose and analyze domestic and foreing cases factors. For practical analysis and application on a certain local city's characteristics from a design point of view, way of local development and cultural industry in the city have been researched.
김남훈,김병욱 한국패키지디자인학회 2002 상품문화디자인학연구 Vol.11 No.-
The design of a Web home page plays a critical role in the effective transmission of messages by approaching with visual images. The transmission of the intended information cannot be made can induce the interest of the viewers. Contemporary information-oriented cultures lays heavy importance on industrial design, especially on the design of Web home page. The most critical problem is the lack of professional experience and knowledge in the design of Web home page, which is caused largely by the short history of using Internet. It results in the poor awareness of the role and significance of the design of the Web home page and of the professional designers, currently, the home page design has been led not by the professional designers or artists but by those computer engineers and information processing technicians. As the result, hypocritical formats and appearances which are short of creativity and significance of the design of the Web home page and of the professional designers, currently, the home page design has been led not by the professional designers or artists but by those computer engineers and information processing technicians. As the result, hypocritical formats and appearances which are short of creativity and originality are prevalent in the design of current home pages without properly taking into consideration the design elements. In order to establish the role of design in creating the Web home pages, it is required that professional illustrators and photographers be widely employed to work on the design of the home pages. It will allow their works to be creative and differential so as to induce more users. The professional designers, in turn, could be encouraged to take part in the design of the Web home pages. Ultimately, it will make the Internet take the leading role in the multimedia society as a ideal media of communication among the designers and world wide users as well.
NAM, JI-YOUN,SON, KWANG-HEE,KIM, HYAE-KYEONG,HAN, MI-YOUNG,KIM, SUNG-UK,CHOI, JUNG-DO,KWON, BYOUNG-MOG 한국미생물 · 생명공학회 2000 Journal of microbiology and biotechnology Vol.10 No.4
Grb2 is an important adaptor protein in the mitogenic Ras signaling pathway of receptor tyrosine kinases, and contains one SH2 domain and two SH3 domains. The SH2 domain binds to specific phosphotyrosine motifs on receptors or adaptor proteins such as Shc. The SH2 domain antagonists may lead to blocking of the oncogenic Ras signals and to developing new antitumor agents. In the course of screening SH2 antagonists from natural sources, sclerotiorin (1) and isochromophilone Ⅳ (2) were isolated from a strain, Penicilliwn multicolor F 1753, and their structures were established by NMR spectral data. The metabolites significantly inhibited the binding between the Grb2-SH2 domain and phosphopeptide derived from the Shc protein, with IC_50 values of 22μM and 48μM for (1) and (2). respectively. The compounds are the first nonpeptidic inhibitors of the SH2 domain from a natural source.