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3T MREIT 시스템을 이용한 실험견 사체의 두부 도전율 영상
정우철,김영태,김형중,이태휘,강병택,박희명,우응제,Jeong, Woo-Chul,Kim, Young-Tae,Minhas, Atul S.,Kim, Hyung-Joong,Lee, Tae-Hwi,Kang, Byeong-Teck,Park, Hee-Myung,Woo, Eung-Je 대한의용생체공학회 2009 의공학회지 Vol.30 No.2
Magnetic Resonance Electrical Impedance Tomography (MREIT) is a new bio-imaging modality providing cross-sectional conductivity images from measurements of internal magnetic flux densities produced by externally injected currents. Recent MREIT studies demonstrated successful conductivity image reconstructions of postmortem and in vivo canine brain. However, the whole head imaging was not achieved due to technical issues related with electrodes and noise in measured magnetic flux density data. In this study, we used a new carbon-hydrogel electrode with a large contact area and injected 30 mA imaging current through a canine head. Using a 3T MREIT system, we performed a postmortem canine experiment and produced high-resolution conductivity images of the entire canine head. Collecting magnetic flux density data inside the head subject to multiple injection currents, we reconstructed cross-sectional conductivity images using the harmonic $B_z$ algorithm. The conductivity images of the canine head show a good contrast not only inside the brain region including white and gray matter but also outside the brain region including the skull, temporalis muscle, mandible, lingualis proprius muscle, and masseter muscle.