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      • KCI등재

        SARS-CoV-2 IgG Antibody Seroprevalence in Children from the Amritsar District of Punjab

        Amandeep Kaur,Narinder Singh,Kanwardeep Singh,Shailpreet Kaur Sidhu,Harleen Kaur,Poonam Jain,Manmeet Kaur,Mohan Jairath 대한임상검사과학회 2022 대한임상검사과학회지(KJCLS) Vol.54 No.3

        The majority of the children experience milder coronavirus disease 2019 (COVID-19) symptoms. Children represent a significant source of community transmission. Children under 18 years of age account for an estimated 4.8% of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections globally. However, no conclusive statements pertaining to the multi-fold aspects of the virus in children could be drawn due to the lower prevalence of pediatric cases. The present study was conducted to identify the indirect impact of SARS-CoV-2 infections on developing herd immunity among children in the age group 3 to 18 years by investigating their antibody levels. In the study, 240 children aged 3∼18 years were recruited by the Department of Pediatrics, Government Medical College and Hospital, Amritsar, India, and quantification of the antibodies was performed at the Viral Research and Diagnostic Laboratory (VRDL), Government Medical College (GMC), Amritsar, India. Out of the 240 serum samples, 197 (82.08%) showed seropositivity, while 43 (17.92%) were seronegative. When stratified, it was observed that in the age group 3∼6 years, 22.33% of children were found to have anti-SARS-CoV-2 antibodies while in the age groups 7∼10 years, 11∼14 years, and 15∼18 years, respectively, 37.06%, 30.46%, and 10.15% were seropositive. Although there was seroconversion among children which was useful for predicting the next wave, no differences in seropositivity were observed between adults and children.

      • Comparative Performance of Health Insurance Business of Public and Private General Insurance Companies in India

        Amandeep Kaur Shahi,Harinder Singh KINFORMS 2015 Management Review Vol.10 No.1

        The study is an endeavour to analyse the comparative performance of health insurance business of public and private general insurance companies for the period from 2006-07 to 2011-12 using the Mann- Whitney Test. The comparative performance of the health insurance business of 4 public, 8 private general insurance companies and 2 standalone health insurance companies has been examined using the Claim Ratio and Net Retention Ratio. These ratios have been analysed and interpreted by calculating mean, median, standard deviation and coefficient of variation. It has been found that the mean of claim ratio was -2.82 (p>0.05) and mean of net retention ratio was -1.98 (p>0.05) which showed significant difference between the claim ratio and net retention ratio of health insurance business of public and private general insurance companies.

      • KCI등재

        Erythrocyte Sedimentation Rate: Its Determinants and Relationship with Risk Factors Involved in Ischemic Stroke

        ( Kirandeep Kaur ),( Amandeep Kaur ),( Anupam Kaur ) 대한임상검사과학회 2022 대한임상검사과학회지(KJCLS) Vol.54 No.1

        Erythrocyte sedimentation rate (ESR) evaluation is a useful tool for monitoring disease activity in various inflammatory and non-inflammatory conditions. ESR is known to be influenced by a multitude of confounding factors. The present study aimed to assess the possible determinants of the ESR and its relationship with various risk factors involved in ischemic stroke. ESR and other hematological and biochemical parameters were investigated in 163 ischemic stroke patients (107 males and 56 females) selected based on imaging techniques including magnetic resonance imaging (MRI) or computed tomography (CT) scans. Statistical analysis was performed using the SPSS 16.0 software. Linear regression analysis showed a significant inverse relationship of hemoglobin (Hb) and hematocrit or packed cell volume (PCV) (P<0.001 for females; P<0.01 for males) with the ESR. It was observed that the red blood cell (RBC) count was not strongly correlated with the ESR (P<0.05 for both males and females). It was also observed that sex significantly affected the variables determining the ESR levels, whereas age had no effect. Gender differences were also observed with respect to Hb, RBC, PCV, mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), and ESR. The possible determinants of higher ESR levels in ischemic stroke may be sex, Hb, hematocrit, and RBC count, but the role of other clinical and laboratory parameters cannot be underestimated.

      • KCI등재

        Antennas for Biomedical Applications

        Gurveer Kaur,Amandeep Kaur,Gurpreet Kaur Toor,Balwinder S. Dhaliwal,Shyam Sundar Pattnaik 대한의용생체공학회 2015 Biomedical Engineering Letters (BMEL) Vol.5 No.3

        Biomedical engineering today holds a prominent place as a means of improving medical diagnosis and treatment, and as an academic discipline. Today glucose monitoring, insulin pumps, deep brain simulations and endoscopy are a few examples of the medical applications that can take advantage of remote monitoring system and body implantable unit. Body implantable devices are widely researched for humans, in the applications such as monitoring blood pressure and temperature, tracking dependent people or lost pets, wirelessly transferring diagnostic information from an electronic device implanted in the human body for human care and safety, such as a pacemaker, to an external RF receiver. Antennas can be implanted into human bodies or can just be mounted over the torso (skin-fat-muscle) to form a bio-communication system between medical devices and exterior instruments for short range biotelemetry applications. In addition to the clear benefits to the healthcare system provided by body implanted devices, economical aspects are also relevant. Remote monitoring systems facilitate the diagnosis of diseases and favor the hospital at home by reducing the hospitalization period.

      • Capacitance Scaling Based Energy Efficient and Tera Hertz Design of Malayalam Unicode Reader on FPGA

        Amanpreet Kaur,Furqan Fazili,Sunny Singh,Vaishali Sharma,Amandeep Singh,Md Hashim Minver 보안공학연구지원센터 2015 International Journal of u- and e- Service, Scienc Vol.8 No.8

        Malayalam is Kerala's official language, south-western region of India mainly speak this language, and very less research has been done for designing Malayalam Unicode reader. The Unicode range of characters for Malayalam script is 0D00–0D7F. In this work, we are focusing on the script of Malayalam language and its Unicode required for coding in Hardware Descriptive Language. This paper covers the hardware design and implementation of Malayalam Unicode Reader (MUR) for Kairali scripts on Virtex-6 FPGA. This MUR design was tested with the device operating at frequency of 1THz, Capacitance has been varied from 1pF to 25pF with SSTL family (Stub Series Terminated Logic) with an interval of 5pf.

      • KCI등재

        Application of QbD based approach in method development of RP-HPLC for simultaneous estimation of antidiabetic drugs in pharmaceutical dosage form

        Deepika Thakur,Amandeep Kaur,Suraj Sharma 한국약제학회 2017 Journal of Pharmaceutical Investigation Vol.47 No.3

        The aim of the proposed study was to develop a novel sensitive and rugged stability indicating HPLC method based on an approach of fractional factorial design (FFD) for the simultaneous of estimation of gliclazide and metformin hydrochloride without prior separation in tablets. Preliminary experiments were conducted to identify the critical attribute factors and using Taguchi screening method to assess risk management method process parameters. Later on FFD was applied to optimize the resolution as response between both drugs in short run time. Sixteen experimental runs were performed from grid search data using design of expert software v.7.0. Furthermore, the optimized method was then validated according to the ICH guidelines. The generated model using FFD for the resolution was found to be highly statistically significant (p\0.05) and after analyzing the optimized zone within the design space, the final chromatographic conditions were selected as mobile phase 60:20:20:0.5, pH 7.5, flow rate 1.0 ml/min and column temperature 25 C using analytical column C18 Nucleosil ODS (250 9 4.6 mm2 i.d, 5 l) at 227 nm of detector wavelength. Validation of the developed method by QbD has manifested the specificity, accuracy and excellent linearity range and correlation values (R2) 0.997 and 0.996 for drugs. From the analysis it was measured that their LOD and LOQ values for the drugs were 0.035, 0.080 lg/ml and 0.40, 0.55 lg/ml. Therefore, a novel sensitive, accurate and stability indicating method was developed with high degree of practical utility of both drugs estimation in pharmaceutical dosage forms.

      • KCI등재

        USE OF QUANTUM MECHANICAL FRAGMENTATION APPROACH IN DECAY DYNAMICS OF 221FR NUCLEUS

        MANOJ K. SHARMA,AMANDEEP KAUR 장전수학회 2021 Proceedings of the Jangjeon mathematical society Vol.24 No.4

        The ground state and excited state decay dynamics of 221Fr nucleus is studied using the quantum mechanical fragmentation theory (QMFT) based methodology. The decay paths of ground state 221Fr nucleus, i.e. α-decay, cluster emission and spontaneous fission (SF), are explored within the preformed cluster model (PCM). The relative contribution of these decay modes is investigated in terms of fragmentation potential and preformation probability P0. The calculations are made for the spherical as well as deformed choice of decaying fragments. Here, the deformation effects are included upto quadrupole (β2) shapes of nuclei with ‘hot-compact’ and ‘cold-elongated’ optimum orientations. The halflife times (T1/2) of α particle and 14C cluster are calculated using β2-deformed fragmentation, and find reasonable agreement with the experimental data. The spontaneous fission decay fragments are identified for 221Fr parent nucleus and corresponding decay half-life time is predicted. Further, the excited state decay of 221Fr compound nucleus formed in 19F+202Pt reaction is studied at excitation energy E*CN=10 MeV within the framework of the dynamical cluster-decay model (DCM). Note that DCM is an extended version of PCM, where temperature (T) and angular momentum (ℓ) are duly incorporated. The evaporation residue (ER) and fusion-fission (ff) cross-sections are calculated using hot-compact fragmentation approach. Finally, a relative study of spontaneous fission and induced fission is presented in terms of barrier characteristics and potential energy surfaces.

      • KCI등재

        Effect of pre-operative medication with paracetamol and ketorolac on the success of inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: a double-blind randomized clinical trial

        Kumar, Umesh,Rajput, Akhil,Rani, Nidhi,Parmar, Pragnesh,Kaur, Amandeep,Aggarwal, Vivek The Korean Dental Society of Anesthsiology 2021 Journal of Dental Anesthesia and Pain Medicine Vol.21 No.5

        Background: The efficacy of local anesthesia decreases in patients with symptomatic irreversible pulpitis. Therefore, it was proposed that the use of premedication with an anti-inflammatory drug might increase the success rate of pulpal anesthesia in mandibular posterior teeth with vital inflamed pulp. Methods: One hundred thirty-four patients who were actively experiencing pain willingly participated in this study. The Heft Parker (HP) visual analog scale (VAS) was used to record the initial pain intensity. Patients were randomly allocated to receive a placebo, 10 mg of ketorolac, and 650 mg of paracetamol. The standard inferior alveolar nerve block (IANB) was administered to all patients using 2% lidocaine with 1:200,000 adrenaline after one hour of medication. After 15 min, the patient was instructed to rate the discomfort during each step of the treatment procedure, such as access to remaining dentin, access to the pulp chamber, and during canal instrumentation on the HP VAS. IANB was considered successful if the patient reported no or mild pain during access preparation and instrumentation. Moderate or severe pain was classified as a failure of IANB and another method of anesthesia was used before continuing the treatment. Results: The rate of successful anesthesia in the placebo, paracetamol, and ketorolac groups was 29%, 33%, and 43%, respectively, and no statistically significant difference was found between the groups. Conclusion: Preoperative administration of paracetamol or ketorolac did not significantly affect the success rate of IANB in patients with irreversible pulpitis. No significant difference was observed between the paracetamol and ketorolac groups.

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