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- 저자 : Amal Yassin (검색결과 2 건)
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El Ghallab Yassine,Al Jahid Abdellah,Jamal Eddine Jamal,Ait Haj Said Amal,Zarayby Lhoussaine,Derfoufi Sanae 경희대학교 융합한의과학연구소 2020 Oriental Pharmacy and Experimental Medicine Vol.20 No.2
Syzygium aromaticum L. is a popular flavor and fragrance spice used in cooking, traditional and modern therapy. No work has compared between the scavenging capacity of the essential oil, extracts and eugenol, or studied that of the hexane extract, as well as its phenolic and flavonoid contents. To reveal more details on phytochemical and scavenging characteristics of Syzygium aromaticum spice, we estimated the scavenging activity of the essential oil, each extract of water, ethanol, ethyl acetate and hexane obtained from clove buds, based on their effective concentration able to scavenge 50% (EC50) of 2,2′-diphenyl-1-picrylhydrazyl, and 2,2′-azinobis (3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt free radicals. The essential oil showed high scavenging activity (EC50 of 0.40 ± 0.06 and 0.42 ± 0.02 mg/ml), and comprises 13 identified compounds. Eugenol, β-Caryophyllene, eugenyl acetate and α-Humulene are the major components. Comparing extracts, those of ethanol and hexane exhibited the greatest phenolic content (351.83 ± 17.90 and 348.04 ± 24.54 mg of gallic acid equivalent/gextract respectively) and the potent scavenging activities (EC50 of 0.41 ± 0.03 and 0.37 ± 0.00 mg/ml respectively). A moderate flavonoid content was observed, and aqueous extract was the best (21.90 ± 0.16 mg of quercetin equivalent/gextract). According to thin layer chromatography screening, all extracts content eugenol except that of water, this phenol contributes mainly on the scavenging activity and seems to be more active in mixture with terpenes, like in essential oil.
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Reduced Fertility and Fecundity among Patients with Bipolar I Disorder and Schizophrenia in Egypt
Hader Mansour,Kareem Kandil,Warda Fathi,Mai Elassy,Ibtihal Ibrahim,Hala Salah,Amal Yassin,Hanan Elsayed,Salwa Tobar,Hala El-Boraie,Ahmed Eissa,Mohamed Elhadidy,Nahed E. Ibrahim,Wafaa El-Bahaei,Vishwaj 대한신경정신의학회 2011 PSYCHIATRY INVESTIGATION Vol.8 No.3
Objective To evaluate reproduction among patients with bipolar I disorder (BP1) or schizophrenia (SZ) in Egypt. Methods BP1 patients (n=113) were compared with community based, demographically balanced controls (n=124) and SZ patients (n=79, DSM-IV). All participants were evaluated using structured interviews and corroborative data were obtained from relatives. Standard indices of procreation were included in multivariate analyses that incorporated key demographic variables. Results Control individuals were significantly more likely to have children than BP1 or SZ patients (controls 46.8%, BP1 15.9%, SZ 17.7%), but the BP1-SZ differences were non-significant. The average number of children for BP1 patients (0.37±0.9) and SZ patients (0.38±0.9) was significantly lower than for controls (1.04±1.48) (BP1 vs controls, p<0.001; SZ vs controls, p<0.001). The frequency of marriages among BP1 patients was nominally higher than the SZ group, but was significantly lower than controls (BP1: 31.9% SZ: 27.8% control: 57.3%). Even among married individuals, BP1 (but not SZ) patients were childless more often than controls (p=0.001). The marital fertility, i.e., the average number of children among patients with conjugal relationships for controls (1.8±1.57) was significantly higher than BP1 patients (1.14±1.31, p=0.02), but not significantly different from SZ patients (1.36±1.32, p=0.2). Conclusion Selected reproductive measures are significantly and substantially reduced among Egyptian BP1 patients. The reproductive indices are similar among BP1 and SZ patients, suggesting a role for general illness related variables. Regardless of the cause/s, the impairment constitutes important, under-investigated disability. Objective To evaluate reproduction among patients with bipolar I disorder (BP1) or schizophrenia (SZ) in Egypt. Methods BP1 patients (n=113) were compared with community based, demographically balanced controls (n=124) and SZ patients (n=79, DSM-IV). All participants were evaluated using structured interviews and corroborative data were obtained from relatives. Standard indices of procreation were included in multivariate analyses that incorporated key demographic variables. Results Control individuals were significantly more likely to have children than BP1 or SZ patients (controls 46.8%, BP1 15.9%, SZ 17.7%), but the BP1-SZ differences were non-significant. The average number of children for BP1 patients (0.37±0.9) and SZ patients (0.38±0.9) was significantly lower than for controls (1.04±1.48) (BP1 vs controls, p<0.001; SZ vs controls, p<0.001). The frequency of marriages among BP1 patients was nominally higher than the SZ group, but was significantly lower than controls (BP1: 31.9% SZ: 27.8% control: 57.3%). Even among married individuals, BP1 (but not SZ) patients were childless more often than controls (p=0.001). The marital fertility, i.e., the average number of children among patients with conjugal relationships for controls (1.8±1.57) was significantly higher than BP1 patients (1.14±1.31, p=0.02), but not significantly different from SZ patients (1.36±1.32, p=0.2). Conclusion Selected reproductive measures are significantly and substantially reduced among Egyptian BP1 patients. The reproductive indices are similar among BP1 and SZ patients, suggesting a role for general illness related variables. Regardless of the cause/s, the impairment constitutes important, under-investigated disability.
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