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- 저자 : Aksoy Fatih (검색결과 6 건)
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Aksoy Fatih,Tosun Samet 대한치과보존학회 2022 Restorative Dentistry & Endodontics Vol.47 No.3
Objectives This study aimed to evaluate the effects of 5% lidocaine and 2.5% lidocaine/2.5% prilocaine topical anesthetic on pain during needle insertion and infiltration injection in the labial mucosa of anterior maxillary teeth, and to assess the relationship between patients’ anxiety and pain scores. Materials and Methods The Modified Dental Anxiety Scale questionnaire was applied and recorded. Patients were randomly divided into 4 groups (n = 30), as follows: G1 group: 5% lidocaine and placebo for 1 minute, G2 group: 2.5% lidocaine/2.5% prilocaine and placebo for 1 minute, G3 group: 5% lidocaine and placebo for 3 minutes, and G4 group: 2.5% lidocaine/2.5% prilocaine and placebo for 3 minutes. Before the application of topical anesthesia, one side was randomly selected as the topical anesthesia and the contralateral side as the placebo. The pain levels were measured with Visual Analog Scale (VAS) immediately after needle insertion and injection and were compared. The correlation between anxiety and pain scores was analyzed. Results Administration of 5% lidocaine for 1 minute had significantly higher pain scores for both insertion and infiltration injection than the other groups (p < 0.05). There was a significant moderate positive correlation between dental anxiety and the injection-induced VAS pain score in the placebo side in all groups (p < 0.05). Conclusions Topical anesthetics significantly reduced the pain caused by both needle insertion and injection pain in comparison to the placebo side. The pain scores of patients with dental anxiety were lower on the topical anesthesia compared to the placebo side. Trial Registration Thai Clinical Trials Registry Identifier: TCTR20201217002
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Quality and Nutritional Property Changes in Stored Dried Apricots Fumigated by Sulfur Dioxide
Fatih Sen,Mustafa Ozgen,Bayram Murat Asma,Uygun Aksoy 한국원예학회 2015 Horticulture, Environment, and Biotechnology Vol.56 No.2
Apricots are grown in many countries and are marketed as dried or fresh. Sulfur fumigation is preferred as a low-cost pre-treatment to maintain apricot color. This study aims to determine the effect of sulfur dioxide (SO2) concentration on quality and nutritional properties of dried apricot fruits during storage. Apricot fruits were treated with different concentrations of SO2 (1,250, 2,000, and 3,500 mg・kg-1) and then stored at 20°C under 50-65% relative humidity conditions for 18 months. Fruit SO2 concentration decreased rapidly during the initial stage and then decreased at a slower rate. Fruit color darkening became more pronounced after 12 months, especially in the fruit treated with 1,250 and 2,000 mg・kg-1 SO2. After 18 months of storage, total phenolic content (839-890 mg GAE 100 g-1dry weight), antioxidant activity (9.4-11.6 μmol TE g-1 dry weight), and β-carotene levels (42.7-47.6 mg・kg-1) of all treatments varied only slightly, despite lower values overall. Therefore, SO2 levels must be chosen based on the expected storage conditions and length of the storage period.
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Optimization of Magnesium Phosphide Treatment Used to Control Major Dried Fig Storage Pests
Kamer Betul Meyvaci,Fatih Sen,Uygun Aksoy 한국원예학회 2010 Horticulture, Environment, and Biotechnology Vol.51 No.1
Methyl bromide (MeBr), a fumigant widely used to control storage pests in dried fruit and nut industry, is banned for use because of ozone layer depletion according to the Montreal Protocol. Dried fig industry is the most affected from MeBr ban due to prevalence of storage pests namely fig moth (Ephestia cautella). Magnesium phosphide was tested for exposure times of 3 and 5 days at 0.70 g · m?³ phosphine (PH₃) and 1.33 g · m?³ PH₃ of dried fig in gas-tight storage units containing 15 ton of dried figs in boxes of 25-30 ㎏ to control two major pests of dried figs, fig moth and fig mite (Carpoglyphus lactis). The control fruits were fumigated with MeBr at 40 g · m?³ for 24 h. The results proved that the tested concentrations and exposure periods to PH₃ provided that 100% mortality of the test species. After exposure to PH₃ or MeBr, fruit quality was preserved under ambient storage conditions for 4 months. The lower dosage of PH₃ does not cause any adverse effect on fruit quality.
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Mehmet Cemal Kaya,Yasin Bez,Ibrahim Fatih Karababa,Ali Emhan,Nurten Aksoy,Mahmut Bulut,Mehmet Gunes,Abdullah Atli,Salih Selek 대한신경정신의학회 2013 PSYCHIATRY INVESTIGATION Vol.10 No.3
Objective In recent years, many published studies have focused on the relationship between oxidative stress and psychiatric disorders. However, studies in generalized anxiety disorder (GAD) are few despite relatively high prevalence rates. In an attempt to fill this gap in the literature we aimed to measure serum levels of free sulphydryl, an important member of antioxidant defense mechanisms, of the patients with GAD. Methods A total of 35 (23 female, 12 male) GAD patients without any other co-morbid medical or psychiatric disorder and 35 (23 female, 12 male) healthy controls have been included in the study. Disease severity of the patients were quantified by using the Hamilton Anxiety Rating Scale (HAM-A). Serum free sulphydryl group levels of patients and healthy controls were measured in an appropriate way. Results Mean level of serum sulphydryl groups was significantly lower in the patient group. There was a negative correlation between their level and the disease duration. However, they did not show any significant correlation with the disease severity. Conclusion Decreased serum sulphydryl level observed in pure GAD patients suggests an increased oxidative stress in these patients. Well designed future researches are needed to replicate our findings and to test the implications of the present study.
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Evaluation of Oxidant/Antioxidant Status and Cytokine Levels in Patients with Cannabis Use Disorder
Huseyin Bayazit,Salih Selek,Ibrahim Fatih Karababa,Erdinc Cicek,Nurten Aksoy 대한정신약물학회 2017 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.15 No.3
Objective: Cannabis is the most commonly used illegal drug in the world and it has several adverse effects such as anxiety, panic reactions and psychotic symptoms. In this study, we aimed to evaluate oxidant, anti-oxidant status and cytokine levels in individuals with cannabis use disorder. Methods: Thirty-four patients with cannabis use disorder and 34 healthy controls were enrolled to the study. Serum total antioxidant status, total oxidant status and cytokine levels were investigated in patients with cannabis use disorder and healthy controls. Results: We found increased levels of total oxidant status, oxidative stress index and interleukin (IL) 1, IL-6, IL-8, and tumor necrosis factor (TNF) in individuals with cannabis dependency compared to healthy people. When we compared total antioxidant status, IL-12, and interferon (IFN) levels, there were no differences in both groups. There was positive correlation between IL-6 and total oxidant status, oxidative stress index levels. Conclusion: The oxidative balance of individuals with cannabis use disorder was impaired and they had higher levels of IL-1, IL-6, IL-8, and TNF-, which is a pro-inflammatory cytokine and indicates increased inflammation compared to healthy controls. Thus, these findings suggest that cannabis increased inflammation and impaired the oxidative balance.
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