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Asih Triastuti,박희준,Jongwon Choi 한국생약학회 2009 Natural Product Sciences Vol.15 No.1
Oxidative stress is caused by an imbalance between the production of reactive oxygen and an ability of a biological system, to readily detoxify the reactive intermediates or easily repair the resulting damage. It has been suggested that developmental alloxan-induced liver damage is mediated through increases in oxidative stress. The anti-diabetic effect and antioxidant activity of Phaleria macrocarpa (PM) fractions were investigated in alloxan-induced diabetic rats. After two weeks administration of PM, the liver antioxidant enzyme and hyperglycemic state were evaluated. The results showed that oral administration of PM treatments reduced blood glucose levels in diabetic rats by oral administration (P < 0.05). Serum glutamic-oxaloacetic transaminase (sGOT) and serum glutamic-pyruvate-transaminase (sGPT) were also diminished by PM supplementation. The superoxide dismutase (SOD), catalase (CAT) and glutathione-peroxidase (GPx) activities, and glutathione (GSH) level in the alloxan-induced diabetic rats were significantly decreased (P < 0.05) compared to those in the normal rats but were restored by PM treatments. PM fractions also repressed the level of malondialdehyde (MDA) in the liver. Glutathione reductase (GR), glutathione-S-transferase (GST) and γ-glutamylcysteine synthase (GCS) were also reduced in alloxan-induced diabetic rats. PM fractions could restore the GR and GST activities, but the GCS activity was not affected in rat livers. From the results of the present study, the diabetic effect of the butanol fraction of PM against alloxan-induced diabetic rats was concluded to be mediated either by preventing the decline of hepatic antioxidant status or due to its indirect radical scavenging capacity.
Asih Triastuti,박희준,Jong Won Choi 한국생약학회 2009 Natural Product Sciences Vol.15 No.3
The protective effects of Phaleria macrocarpa (PM) against oxidative stress in diabetic rats were investigated. Diabetes was induced in male Sprague Dawley rats using alloxan (150 mg/kg i.p). After the administration of PM fractions for two weeks the diabetic symptoms, nephropathy and renal antioxidant enzymes were evaluated. The results showed that the oral PM treatments reduced blood glucose levels in diabetic rats. The PM fractions decreased kidney hypertrophy and diminished blood urea nitrogen (BUN) in diabetic rats. Malondialdehyde (MDA), a lipid peroxidation marker, was increased in diabetic animals, but was suppressed by the PM treatments. In addition, the superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) activities, and glutathione (GSH) level in the alloxan-induced diabetic rats were significantly decreased compared with those in the normal rats, but were restored by PM treatments. The PM fractions also suppressed the level of MDA in the kidney. In conclusion, the anti hyperglycemic and anti-nephropathy of P. macrocarpa may be correlated to the increased renal antioxidant enzyme activity in the kidney.
WULANDARI, Asih Marini,RAHAYU, Sri Mangesti,SAIFI, Muhammad,NUZULA, Nila Firdausi Korea Distribution Science Association 2022 The Journal of Asian Finance, Economics and Busine Vol.9 No.8
The purpose of this study was to determine the relationship between company risk and factors such as business size, ownership structure, and leverage. The study was conducted on 142 manufacturing sector companies listed on the Indonesia Stock Exchange from 2013 to 2018. The purposive sampling method was used to select the research sample. The sample size for this study was 21 different companies. The analytical approach uses Structural Equation Modeling (SEM) with WarpPLS. According to the findings of the investigation, the size of the company has a significant influence on both the amount of leverage the company uses and the amount of risk the company takes. The level of leverage is significantly influenced by the ownership structure. However, the ownership structure does not have a significant impact on the level of risk the company; rather, leverage has a big impact on the level of risk the company faces. The findings of this study are helpful to prospective investors in measuring the risk posed by the company to make judgments regarding investments. The findings of this study are also essential for management to consider while controlling the risk of the organization.
RICE DRIER INSTRUMENT FOR DIABETICS
Safira Candra Asih 국제과학영재학회 2013 APEC Youth Scientist Journal Vol.5 No.-
Number of diabetics in the world is ever increasing. According to data of WHO, it is estimated there are 366,210,100 people suffering from diabetes. Whereas in Indonesia, diabetics will reach 171,230,000 in 2030. In addition, Indonesia ranks fourth highest number of diabetics in the world after China, India, and the United States. Diabetics are advised to consume foods in low carbohydrates and high fiber. In Indonesia, rice is taken as staple food for the people, though, the rice has content of high carbohydrate and low fiber. On the other hand, a study of resistant starch (RS) turns out good effect for digestive health so it is beneficial for diabetics. Cooking of parched rice or processed rice undertaken at twice is a form of resistant starch. Cooking at twice means the cooked rice has been drained out and cooked again. Unfortunately the drying process takes long time, inefficient, and even unhygienic. Authors took the initiative to create an instrument that helps to dry faster and more rice. This instrument takes 45 minutes enough to dry it out. Its work principle is the rice placed in a rotary tube while heating it with the results of evenly dried out. As a result the rice can be taken as diet for diabetics. People can still eat rice with the same amount but with lower glycemic index.
RICE DRIER INSTRUMENT FOR DIABETICS
Safira Candra Asih 국제과학영재학회 2014 APEC Youth Scientist Journal Vol.6 No.1
Number of diabetics in the world is ever increasing. According to data of WHO, it is estimated there are 366,210,100 people suffering from diabetes. Whereas in Indonesia, diabetics will reach 171,230,000 in 2030. In addition, Indonesia ranksfourth highest number of diabetics in the world after China, India, and the United States. Diabetics are advised to consume foods in low carbohydrates and high fiber. In Indonesia, rice is taken as staple food for the people, though, the rice has content of high carbohydrate and low fiber. On the other hand, a study of resistant starch (RS) turns out good effect for digestive health so it is beneficial for diabetics. Cooking of parched rice or processed rice undertaken at twice is a form of resistant starch. Cooking at twice means the cooked rice has been drained out and cooked again. Unfortunately the drying process takes long time, inefficient, and even unhygienic. Authors took the initiative to create an instrument that helps to dry faster and more rice. This instrument takes 60 minutes enough to dry it out. Its work principle is the rice p laced in a rotary tube while heating it with the results of evenly dried out. As a result the rice can be taken as diet for diabetics. People can still eat rice with the same amount but with lower glycemic index.
Yuni ASTUTI,Daru ASIH 한국유통과학회 2021 The Journal of Asian Finance, Economics and Busine Vol.8 No.4
This research empirically analyzed whether the foods which came from a non-Muslim majority country, such as South Korea, could play an important role in affecting the consumer intention in a predominantly Muslim country. Online survey methods were used to investigate the proposed hypothesis. 318 responses were used for further analysis. Forty-six reflective constructs were adapted from literature and designed by using a five-point Likert scale to facilitate measurement. Estimation models and structural models were examined through SEM-PLS analysis techniques using SmartPLS 3.0 application as the data processing tool. The results showed that religiosity and halal awareness had a positive and significant effect on attitude toward halal labels, including the mediating effect from consumer attitudes towards halal labels which had a positive but insignificant effect on purchase intention. Halal awareness plays an important role for Muslims in the decisionmaking process for purchasing food. In contrast to the initial hypothesis, the country of origin actually did not have a positive effect on attitudes towards the halal label. In a Muslim-majority country like Indonesia, findings halal food is not difficult, so this research basically is a reminder to marketers to follow those halal principles in implementing their marketing strategies.