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안영성,성낙술,함인해,최호영 대한본초학회 2004 大韓本草學會誌 Vol.19 No.3
Objectives: S. polyrhiza and L. paucicostata can be easily seen in the ponds or rice fields of Korea. But korean native Bu-pyung(浮萍) are rarely used for economical reasons, and usually imported. Methods : The examination of the effect related to the immune, Human CD4-T cell proliferation promotion, HL-60 cell differentiation rate, Ig-E and TNF-α content were measured. Results : It can be seen that S. polyrhiza and L. paucicostata is effective on tumors and the immune. Also L. paucicostata was more effective on the production of Ig-E and blood pressure control, while S. polyrhiza was more effective on immune and tumor. Conculsions : Bu-pyung is mostly used on symptoms of measles not erupted(麻疹不透), urticaria and itching(風疹瘙痒), dropsy with decreased urine(水腫尿少) which implies potential effect on immune, tumor and high blood pressure.
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갯기름나물의 根과 莖葉의 면역 및 항암 활성 비교 연구
조용호,성낙술,함인해,최호영 대한본초학회 2004 大韓本草學會誌 Vol.19 No.3
Objectives: Root of Peucedanum japonicum has traditionally been used as medicine but aerial part of P. japonicum has not been used as medicine. In order to examine the possibility of the substitute for the root as medicinal use. This study were performed comparing the activity of the aerial part and root of P. japonicum. Methods: We measured the proliferation of Human CD4- T cells, which are related to immunity, the differentiation of HL-60 cells, and the contents of IL-6, IgE and TNF-α and compared their anti-cancer effect on Hep3B and A549 cells. Results: As for Human CD4- T cells and HL-60 cells, 1.0g/ℓ methanol extract from the aerial part promoted the proliferation of the cells. Conclusion: In conclusion, this study presented that the aerial part of P. japonicum has immunizing and anti-cancer effects as high as its root, which has commonly been used as medicine. There should be more in-depth research on the aerial part of P. japonicum in the future.
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Antioxidant Activities of New Flavonoids from Cudrania tricuspidata Root Bark
이영재,황완균,김성건,이성재,함인해 대한약학회 2009 Archives of Pharmacal Research Vol.32 No.2
Two new flavonoids, hydroxybenzyl flavonoid glycosides (6-p-hydroxybenzyl kaempferol-7-O-β-Dglucopyranoside named cudranian 1 and 6-p-hydroxybenzyl quercetin-7-O-β-D-glucopyranoside named cudranian 2), and 3 known flavonoids (kaempferol-7-O-β-D-glucopyranoside, quercetin-7-O-β-D-glucopyranoside and aromadendrin) were isolated from root bark of Cudrania tricuspidata and their structures were elucidated by spectroscopic methods. These compounds showed remarkable radical scavenging effects against 1, 1-diphenyl-2-picrylhydrazyl (DPPH) and anti-lipid peroxidation efficacy on human low-density lipoprotein by TBARS assay.
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