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- 저자 : 한충섭(Choong Seop Hahn) (검색결과 7 건)
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이민걸(Min Geol Lee),이원수(Won Soo Lee),전수일(Soo Il Chun),한충섭(Choong Seop Hahn) 대한피부과학회 1988 대한피부과학회지 Vol.26 No.1
We reported a case of subcutaneous mass in a 22-year-old lady having unusual histopathologic findings mixed with both features of pilomatricoma and epidermal cyst and the meanings of these peculiar findings were discussed.
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Bowenoid Papulosis 의 전자현미경적 소견
이정복,한충섭,김수일 대한피부과학회 1982 大韓皮膚科學會誌 Vol.20 No.3
A 41 year-old man had dark pigmented papules and plaques, 4 to 15 mm in size, on the proximal portion of the dorsum of the penile shaft and pubic area of 8 months duration. Over next several months, flesh colored, macerated papules, 2 to 4 mm in size, appeared on the left side of the scrotum Light microscopic examination from a pigmented lesion of the penile shaft showed typical findings of Bowen's disease. Ultrastructural findings included: widening of intercellular space, a decrease in the number of desmosomes with microvillous projections, aggregation of tonofilaments, an increase in the mitotic keratinocytes, an increase in the number of melanin granules, and disorganized bundles of tonofilaments surrounding chromosomes. Virus-like particles were not observed. Based on the ultrastructural findings and review of literatures, it seems to be probable that bowenoid papulosis is a clinical variant of Bowens disease.
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좌창에 대한 Fabry 용액과 항생제 ( Chloramphenicol 또는 Clindamycin )를 함유한 Fabry 용액의 국소도포에 의한 치료효과의 비교 연구
이성낙,한충섭,임윤기 대한피부과학회 1982 大韓皮膚科學會誌 Vol.20 No.3
Antibiotic therapy for acne is now considered one of the most effective regimen. Thirty years ago, oral antibiotics were introduced for acne vulgaris and topical preparations have been available by prescription for more than 15 years. Recently, clindamycin, erythromycin and tetracycline were regarded as the most effective and widely used antibiotics. Many authors reported that clindamycin was a mast effective topical antibiotic for acne vulgaris but side effects, i.e., contact dermstitis or pseudomembranous colitis were reported. The author studied the clinical effectiveness and side effects of Fabrys salution, which has been used as an antiseptic and keratolytic agents, and Fabrys solution containing chloramphenicol or clindamycin. Fifty three patients who were followed for 6 weeks were studied. They were divided into three groups: group I was treated with Fabrys solution(F solution), group II was treated with Fabrys solution containing chloramphenicol(F-c solution) and group Ill was treated with Fabrys solution containing clindamycin(F-cd solution). The results were s follows: 1. The total number of leisons in groups treated with F solution, F-c solution, or F-de solution were decreased significantly from the sixth, forth, or third week of treatment and their therapeutic effects at the end of six weeks were estimated as 55%, 55%, or 70%. 2. The numbers of fluorescence under Wood's lamp in groups treated with F solution, F-c solutio, or F-cd solution were decreased significantly from the sixth, second, or first week of treatment. Their therapuetic effects at the end of six weeks were estimated as 65%, 80%, or 90%. 3. The therapeutic effects of papules at the end of the sixth week of treatment I groups treated with F solution, F-c solution, or F-cd solution were estimated as 50%, 65%, or 70%. The therapeutic effects of open codedones at the end of the sixth week of treatment in groups treated with Fsolution, F-c solution, or F-cd solution were 65%, 50%, or 60%. 4. In the case of closed comedones and pustules, cases were too few in number to evalute the therapeutic effects but the number of pustules in the group treated with F-cd solution was significantly dereased from the fifth week of treatment. 5. The side effects were scaling, itching, tightness or erytyhema which were not significantly different among three groups and most of them were mild. It was suggested that they were due to irritation of F soluton. From these data, we may conclude that F-cd solution was superior to F or F-cd solution in effect on acne, especially on inflammatory lesions such as papules and pustules. In addition, counting the nubers of porphyrin fluorescence under Wood's lamp during treatment seemed to be a very simple, convenient and accurate method of evaluating the clinical effectiveness of topical agents in acne.
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Progressive Cribriform and Zosteriform Hyperpigmentation
이정복,이성낙,강진수,고창조,한충섭 대한피부과학회 1981 大韓皮膚科學會誌 Vol.19 No.4
Prosressive cribriform and zosteriform hyperpimentation(PCZH) is a distinctive clinical entity first described by Rower et al. in 1978. It is characterized by a single area of uniformly tan cribriform macular pigmentation in a zosteriform distribution with no preceding history of skin rash, injury or inflammation. It begins well after birth with gradual extension and is not associatad with any other cutaneous or internal abnormalities. Histologically, There is a mild increase in melanin pigment in the basal cell layer and complete absence of nevus cells. Recently, we observed clinical and histological features of 5 cases of PCZH. The age at onset ranged from 4 to 35 years. The lesions were unilaterally distributed on face, neck, chest, or abdomen. Histologically there was a mild increase in melanin pigment in the basal cell layer. PCZH must be differentiated from Becker's hairy nevus which begin with a unilateral lesion of irregularly macular pigmentation but occasionally it may be multiple or bilateral. In early stage, overgrowth of hairs may be absent but after a few years it is usually present. PCZH is characterized by uniformly tan cribriform pigmentation in zosteriform distribution, which is unilateral and does not cross the midline of the body. Overgrowth of hairs is absent even after a few years. So the lesions of Becker's hairy nevus previously reported, which were unilateral and did not cross the midline of the body and did not show overgrowth of hairs even after a few years, must be called progressive cribriform and zosteriform hyperpigmentation.
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이정복,이승헌,박윤기,고창조,한충섭 대한피부과학회 1981 大韓皮膚科學會誌 Vol.19 No.3
Speckled lentiginous nevus is a clinical variant of nevus-cell nevus first described by Stewart et al. in 1978. It is characterized by small, dark hyperpigmentated speckles superimposed on a tannish-brown background. The speckled areas show varying histologic patterns ranging from nevus incipiens to junctional or compound nevus. The back ground shows histologic features of Ientigo simplex. Recently, we observed clinical and histological features of 5 cases of speckled lentiginous nevi. The age of onset ranges from birth to infancy, The locations are face, thigh, back and scapula. One has zosteriform distribution in upper extrernity, chest and back. Histologic features of speckles are junctional or compound nevus. We suggest that the origin of dark speckles may be from the tannish-brown background, lentigo simplex.
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