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오찬석 ( O Chan Seog ),박현정 ( Park Hyeon Jeong ),이준영 ( Lee Jun Yeong ),조백기 ( Jo Baeg Gi ),김동욱 ( Kim Dong Ug ),김춘추 ( Kim Chun Chu ) 대한피부과학회 2003 대한피부과학회지 Vol.41 No.10
N/A Background : STI571, which is a selective inhibitor of the BCR-ABL tyrosine kinase, is a promising new drug for the treatment of patients with chronic myelogenous leukemia. But it has been noted that this drug is frequently associated with an adverse cutaneous reaction. Objective : The purpose of this study was to find the clinical and histopathological characteristics of drug eruptions caused by STI571. Method : We reviewed the clinical records of 10 patients diagnosed as drug erupions caused by STI571. Result : 1. The mean age was 36.4 years and it was observed predominantly in females as the sex ratio of 7:3. 2. The most common clinical type was exanthematous eruption(70%), and followed by erythema multiforme-like eruption(20%), urticarial eruption(10%). In most cases(90%), the distribution was generalized, which involved trunk and extremities. 3. The mean latent period was 17.1 days and peak incidence(70%) was noted between 1 and 2 weeks. 4. Commonly associated adverse effects included fever(60%) and diarrhea(30%). 5. Histopathologically, common findings included perivascular inflammatory cell infiltration(100%), eosinophil(80%), exocytosis(80%). Conclusion : Because drug eruptions caused by STI571 are dose-related and develop with a high frequency, we need a careful monitoring of patients who are treated with STI571, especially with a high dose.(Korean J Dermatol 2003;41(10 : 1291~1296)
급성 피부 이식편 대 숙주질환의 임상 및 병리학적 고찰
이지선 ( Lee Ji Seon ),박현정 ( Park Hyeon Jeong ),이준영 ( Lee Jun Yeong ),조백기 ( Jo Baeg Gi ),강창석 ( Kang Chang Seog ),김춘추 ( Kim Chun Chu ) 대한피부과학회 2003 대한피부과학회지 Vol.41 No.9
Background : Graft-versus-host disease (GVHD) refers to the spectrum of organ dysfunction that occurs when immunocompetent leukocytes attack specific tissue in a relatively immunocompromised host. The most common clinical setting for GVHD is after bone ma
김지은 ( Kim Ji Eun ),박현정 ( Park Hyeon Jeong ),이준영 ( Lee Jun Yeong ),조백기 ( Jo Baeg Gi ),이인용 ( Lee In Yong ),이원구 ( Lee Won Gu ),고창조 ( Go Chang Jo ) 대한피부과학회 2003 대한피부과학회지 Vol.41 No.9
Since 1982, 31 cases of tick bites were reported in Korea and only one case of Haemaphysalis longicornis related to tick bites was included. Until now, nymph related or multiple tick(more than three) related to tick bites were not reported in the Korean l
정유진 ( Jeong Yu Jin ),이창남 ( Lee Chang Nam ),박현정 ( Park Hyeon Jeong ),오신택 ( O Sin Taeg ),이준영 ( Lee Jun Yeong ),조백기 ( Jo Baeg Gi ) 대한피부과학회 2004 대한피부과학회지 Vol.42 No.4
Acrometastasis is rare and accounts for 0.1% of all metastasis. Renal cell carcinoma accounts for only 10% of this infrequent site. It is usually the late manifestation of a disseminated tumor, but may also be the primary manifestation of an occult cancer. Clinically, it may mimic benign tumors or nonneoplastic osteoarthritic conditions, thus resulting in misdiagnosis and improper treatment. We reported a case of acrometastasis in a renal cell carcinoma in a 76-year-old man who had been diagnosed with a progressed renal cell carcinoma with metastasis of the lung and brain. (Korean J Dermatol 2004;42(4):472~477)
이창남 ( Lee Chang Nam ),모현진 ( Mo Hyeon Jin ),김지은 ( Kim Ji Eun ),박현정 ( Park Hyeon Jeong ),이준영 ( Lee Jun Yeong ),조백기 ( Jo Baeg Gi ),이인용 ( Lee In Yong ) 대한피부과학회 2003 대한피부과학회지 Vol.41 No.9
Lyme disease (Lyme borreliosis) is a vector-borne infection primarily transmitted by Ixodes species and caused by a spirochete, Borrelia burgdorferi. This disease affects multiple areas such as skin, joints, eyes, nervous and cardiovascular systems. Eryth