http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : 정동국(Dong Guk Chung) (검색결과 3 건)
- 무료
- 기관 내 무료
- 유료
-
혈액 투석중인 만성신부전 환자에서 투석막의 생체 적합성에 관한 연구
정동국(Dong Guk Chung),장미경(Mi Kyung Chang),김난희(Nan Hee Kim),이영호(Young Ho Lee),구자룡(Ja Ryong Koo),차대룡(Dae Ryong Cha),권영주(Young Joo Kwon),조원용(Won Young Cho),김형규(Hyoung Kyu Kim) 대한내과학회 1995 대한내과학회지 Vol.48 No.2
N/A beginning and end of each phase. Control blood samples were obtained from 10 healthy adults. The results are as follows. Results: 1) Serume β2 microglobulin in patient group were significantly elevated than in the normal control group (28.32±11.18 vs 1.17±0.18㎍/dl, p<0.05). In phase 1 and phase 3, there are significant (p<0.05) elevation of serum β2 microglobulin, namely from 28.32±11.28 to 31.89±8.38 and from 35.00±11.29 to 38.27±12.42㎍/ml, respectively. But in phase 2, dialysis with PMMA membrane, there was no significant change in serum β2 microglobulin level. 2) Serum soluble interleukin 2 receptor (sIL-2R) levels were markedly elevated in patient group (1564±712 vs 495±105μ/ml, p<0.05). There were significant elevation of sIL-2R level in phase 1 and phase 3, from 1564±713 to 1928±542 in phase 1 and from 1744±508 to 1958±634 U/ml in phase 3. Hut in phase 2, serum sIL-2R level did not change significantly. 3) There were no significant difference of interleukin 2 receptor (IL-2R) expression in peripheral lymphocyte between patient group and normal control. Also there are no significant changes of IL-2R expression according to dialysis membrane. 4) Other immunologic parameters, serum C3 level, T4/T8 cell ratio and NK/T cell ratio are decreased significantly in patient group. But there are no significant changes in serum level according to each phase. Conclusions: Above results suggest that chronic dialysis with Cuprophan membrane may be a factor in the immune deficiency status in chronic renal failure. Because PMMA membrane results in less elevation in β2-microglobulin and sIL-2R, it may be suggested that Cuprophan membrane may be more bioincompatible than PMMA membrane. But further study is required.
-
조원용(Won Yong Cho),김인옥(In Ok Kim),정동국(Dong Guk Chung),김형규(Hyoung Kyu Kim),원남희(Nam Hee Won),박희봉(Hee Bong Park) 대한내과학회 1987 대한내과학회지 Vol.33 No.5
N/A To assess the clinical significance of immune doposits in the clinical course of minimal change nephrotic syndrome, we have studied 27 patients with minimal change nephrotic syndrome, aged from 13 to 51 years. The clinical course of 13 patients with mesangial immune deposits was compared with those of 14 patients without mesangial immune deposits. The results obtained in this study were as follows 1) In IF positive group, serum abumin level was 1.57±0.25 gm/dl and 24 hour urine protein 9.50±4.45 gm/day. In IF negative group, serum albumin level was 1.40±0.34 gm/dl and 24 hour urine protein 11.44±8.67 gm/day. There were no significant differences between two groups. 2) The presenting symptoms such as hypertension, hematuria, and azotemia were appeared in variable ratio, but no significant difference in two groups were noted. 3) In IF positive group, all cases had IgM deposits in mesangium, and two cases had IgA deposits in mesangium. There were no significant differences in symptoms, signs and responses to therapy according to varieties of immunoglobulin or complement deposits. 4) In the clinical course along the steroid therapy, there were no significant differences in the two groups, namely, in IF positive group, complete remission occurred in 46%, and in IF negative group complete remission occurred in 61.5%, somewhat higher ratio, but had no significant difference. There were no difference in any particular clinical onset, histologic pattern on light microscopy, therapy response or clinical course in two groups in our relatively short follow up period. So we concluded that immune deposits is not a marker for response to therapy in patients with idiopathic nephrotic syndrome and that to define new disease entity, IgM nephropathy, further study and follow up were required.
-
한국형 출혈열 환자에서 혈장 Catecholamine의 변화
정동국,최태승,김용섭,류승관,조원용,김형규,원동준 대한내과학회 1990 대한내과학회지 Vol.38 No.1
To evaluate the relationship between plasma catecholamines and the pathogenesis of acute renal failure(AFR), the plasma NE, E, Dopamine, DOPA and DOPAC were measured in 13 cases of Korean hemorrhagic fever(KHF) with renal failure and 12 normal persons as a control group by HPLC with ECD. To correlate these values with other renal functions, the blood pressure(systolic and diastolic), pulse rate, serum creatinine and creatinine clearance were measured. The results were failure as follows: 1) In 13 cases of KHF with renal failure, the plasma NE was increased in the oliguric and diuretic phases compared with the control group(p<0.05). The plasma E was also increased in the diuretic phase(p<0.05). 2) In the follow-up 7 cases, plasma E and NE were decreased in the diuretic phase(p<0.05). 3) The plasma E had a positive correlation with plasma Cr in the oliguric phase and a negative correlation with plasma Cr in the diuretic phase. The plasma NE had a positive correlation with plasma Cr in the diuretic phase. From these results, the increased synthesis of catecholamines is considered to be one of the pathogenic factors in KHF with acute renal failure. And the renal response to changes of catecholamines may be different with each phase in Korean hemorrhagic fever.
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
