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김덕환,이교영,이경갑,최희인,오사메 사토시,이찌조 시게루 충남대학교 수의과대학 동물의과학연구소 1994 動物醫科學硏究誌 Vol.1 No.-
In prder to clarify the changes of serum chemical values(AST, CPK and LDH activities)and LDH isoenzyme fractions in frequent occuring some diseases of dairy cows, total 48 cows(40 patients: 18 with downer cow syndrome, 17 with abomasal displacement and 5 with acute mastitis and 8 controls: clinically healthy cows) were examined. The results obtained were as follows: 1. In changes of total serum enzyme activities of patients group, increase of serum AST(P<0.001), CPK(P<0.01) and LDH activities(P<0.01)were observed in groups of downer cow syndrome and abomasal displacement, respectively by comparison with control group. Increase of AST only was found in group of acute mastitis(P<0.05). 2. In LDH isoenzyme fractions, increase of LDH₁(P<0.01), LDH₂(P<0.05), LDH₃(P<0.01), LDH₄(P<0.01) and LDH_5(P<0.01)fractiona was observed in group of downer cow syndrome and also marker increase of LDH4 and LDH5 fractions was noted in this group. The increase of LDH₁, LDH₂ amd LDH₃ (P<0.01)fractions was found in group of abomasal displacement, but group of acute mastitis showed similar result to that of control group.