반복적으로 시행한 온천요법이 경항통에 미치는 영향

이옥진 ( Yu Chen Li ),최보미 ( Bo Mi Choi ),장선정 ( Sun Jeong Jahng ),안택원 ( Taek Won Ahn ),이정민 ( Jung Min Lee ) 한방재활의학과학회 2013 한방재활의학과학회지 Vol.23 No.3

ObjectivesThe purpose of this study was to investigate the clinical effects of repeatedly performed of balneotherapy on cervical pain. MethodsWe investigate 19 cervical pain subjects in this study. Subjects took 5 session of balneotherapy once a week during 5 weeks. Each session consisted of 15 minutes of high pressure underwater shower (32~36oC) and another 15 minutes of whole body bathing (32~40oC). To evaluate the efficiency of balneotherapy visual analogue scale (VAS) and pain threshold were applied before treatment and after 1st, 2nd, 3rd, 4th, 5th treatment. Then the results were analysed. Results1) The average of VAS significantly decressed from 59.11±14.67 to 33.95± 20.988 after 5 weeks of balneothreapy treatment (p<0.001). 2) The average of pain threshold significantly increased from 5.76±1.294 lbf to 8.74±1.126 lbf after 5 weeks of balneothreapy treatment (p<0.001). ConclusionsBalneotherapy has clinical effscts of pain reduction on cervical pain subjects. Balneotherapy can be used in addition to the Oriental physiotherapy for high effective treatment on cervical pain. Further clinical studies are required to verify these findings. (J Korean Med Rehab 2013;23(3):141-148) ObjectivesThe purpose of this study was to investigate the clinical effects of repeatedly performed of balneotherapy on cervical pain. MethodsWe investigate 19 cervical pain subjects in this study. Subjects took 5 session of balneotherapy once a week during 5 weeks. Each session consisted of 15 minutes of high pressure underwater shower (32~36oC) and another 15 minutes of whole body bathing (32~40oC). To evaluate the efficiency of balneotherapy visual analogue scale (VAS) and pain threshold were applied before treatment and after 1st, 2nd, 3rd, 4th, 5th treatment. Then the results were analysed. Results1) The average of VAS significantly decressed from 59.11±14.67 to 33.95± 20.988 after 5 weeks of balneothreapy treatment (p<0.001). 2) The average of pain threshold significantly increased from 5.76±1.294 lbf to 8.74±1.126 lbf after 5 weeks of balneothreapy treatment (p<0.001). ConclusionsBalneotherapy has clinical effscts of pain reduction on cervical pain subjects. Balneotherapy can be used in addition to the Oriental physiotherapy for high effective treatment on cervical pain. Further clinical studies are required to verify these findings. (J Korean Med Rehab 2013;23(3):141-148)

좌귀환(左歸丸)이 산화적 손상, 염증 및 골절유합 관련 인자에 미치는 영향

이옥진 ( Yu Chen Li ),오민석 ( Min-seok Oh ) 대한한의학회 한방재활의학과학회 2016 한방재활의학과학회지 Vol.26 No.3

Objectives The study was designed to evaluate the healing effects of Joaguihwan (JGH) extract on Anti-oxidation, Anti-inflammatory in RAW 264.7 Cells and factors related with bone metabolism in skull fractured Rat. Methods The fracture healing effect of JGH was measured by scavenging activities of1,1-diphenyl-2-picryl-hydrazyl (DPPH), 2,2``-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid (ABTS) and nitric oxide (NO) in RAW 264.7 cells. The inhibitory effect against the production of inflammatory mediators including interleukin-1β (IL-1β), interleukin-6 (IL-6), tumor necosis factors-α (TNF-α) expression was inhibited in RAW 264.7 cells was experimented using JGH. The effects of JGH on healing fractured rats was measured by osteocalcin, calcitonin, CTXII, TGF-β, BMP-2, Insulin, ALP in the serum. and was checked every 3 weeks from 0 week to 6week using x-ray. Results 1. DPPH free radica and ABTS scavenging activity of JGH were increased according to concentration of JGH in RAW 264.7 Cells. 2. In the experiment, NO, IL-1β, IL-6, TNF-α all showed decrease, in general. Especially NO and IL-1β showed significantly decrease at a concentration of 10, 100 (μg/ml). 3. In the production of osteocalcin in the serum, JGH 200, 400 mg/kg experimental group showed significant increased effect at 2 weeks. 4. In the production of calcitonin in the serum. JGH 200 mg/kg experimental group showed significant increased effect at 4, 6 weeks. JGH 400 mg/kg experimental group showed significant increased effect at 2, 4, 6 weeks. 5. In the production of CTX, TGF-β, BMP-2 in the serum, experimental group showed increased effect. but no significant effect. 6. In the production of insulin in the serum. JGH 200, 400 mg/kg experimental group showed significant decrease effect at 2, 4, 6 weeks. 7. In the production of ALP in the serum. JGH 200 mg/kg experimental group showed significant increased effect at 2, 4, 6 weeks. JGH 400 mg/kg experimental group showed significant increased effect at 4, 6 weeks. 8. In the change of X-ray, the experimental group showed better healing effects on skull fractured rats than control group. Conclusions From above results, JGH showed healing effect on Anti-oxidation, Anti-inflammatory in RAW 264.7 Cells, factors related with bone metabolism in the serum of skull fractured rat and x-ray, which is expected to be applied in clinics. (J Korean Med Rehabil 2016;26(3):31-49)

요추부 염좌 환자에서 다용 경혈에 대한 침치료와 자가운동요법이 미치는 효과

이옥진 ( Yu Chen Li ),허건 ( Gun Huh ),남대진 ( Dae Jin Nam ),이은정 ( Eun Jung Lee ),오민석 ( Min Seok Oh ) 대전대학교 한의학연구소 2014 혜화의학회지 Vol.22 No.2

Objective : The purpose of this study was to investigate the effects of acupuncture treatment on frequently adopted acupuncture point and self exercise therapy for lumbar sprain patient Methods : For this study, a retrospective chart review was conducted. Data are derived from lumbar sprain patients who have received hospital treatment in Daejeon Univ. Cheon-Ahn Korean Hospital. All patients were treated with acupuncture treatment on high frequency acupuncture point (BL25, BL23, BL24, GB30, BL40, BL26, BL60, GB34), physical therapy and herbal medicine and self exercise therapy(Swiss ball exercise, Lumbar stabilization exercise.) We measured visual analogue scale(VAS), Oswestry disability index(ODI), Pain threshold twice(pre-treatment and post-treatment) on 1st day and 5 days later. Results : After being treated, lumbar sprain patients were meaningful improved in VAS, ODI, pain threshold The VAS score, ODI score were statistically decreased after treatment and the pain threshold was statistically increased after treatment. Conclusion : In this study, treatment on frequently adopted acupuncture point and self exercise therapy were effective on lumbar sprain patient.

족관절 염좌의 봉독 약침 치료에 대한 체계적 문헌 고찰

구지향 ( Ji-hyang Gu ),이옥진 ( Yu-chen Li ),조동찬 ( Dong-chan Jo ),이은정 ( Eun-jung Lee ) 대한한의학회 한방재활의학과학회 2018 한방재활의학과학회지 Vol.28 No.3

Objectives To evaluate the evidence supporting the effectiveness of bee venom acupuncture for ankle sprain. Methods We conducted search across 11 electronic databases (Pubmed, EMBASE, Cochrane CENTRAL [CENTRAL], KoreaMed, Kmbase, Koreanstudies Information Service System [KISS], National Digital Science Library [NDSL], Korea Institute of Science and Technology Information [KISTI], China National Knowledge Infrastructure [CNKI], Wanfang and Chinese Scientific Journals Database [VIP] database) to find clinical trials that used bee venom acupuncture as treatment for ankle sprain. The methodological quality of randomized controlled clinical trials (RCTs) were assessed using the Cochrane Risk of Bias (RoB) tool, while non-randomized controlled clinical trials (NRCTs) were assessed using the Cochrane Risk of Bias Assessment tool for Non-randomized Study (RoBANS) tool. Results Four RCTs and one nRCT met our inclusion criteria. Almost studies showed that bee venom acupuncture has positive effect on ankle sprain. 4 studies of same intervention and control included in the meta-analysis. When comparing bee venom acupuncture and acupuncture with acupuncture, the effect size of standardized mean difference (SMD) was -0.19 (95% confidence interval [CI]: -1.95∼1.56, Z=0.55, p=0.83). And when comparing bee venom acupuncture with acupuncture, the effect size of SMD was -0.17 (95% CI: -0.65∼0.31, Z=0.71, p=0.48). Conclusions Although our systematic review found encouraging but limited evidence of bee venom acupuncture for ankle sprain, most of the studies included in the analysis were evaluated as methodologically high risk of bias. From now on further well-designed RCTs should be encouraged. (J Korean Med Rehabil 2018;28(3):55-66)

원발성 월경통의 추나 치료에 대한 체계적 문헌 고찰

서하라 ( Ha-ra Seo ),이옥진 ( Yu-chen Li ),이재은 ( Jae-eun Lee ),김명규 ( Myoung-kyu Kim ) 대한한의학회 한방재활의학과학회 2017 한방재활의학과학회지 Vol.27 No.3

Objectives The purpose of this study is to evaluate the effectiveness of Chuna therapy for primary dysmenorrhea. Methods Researchers searched on 7 electronic databases (Pubmed, National Digital Science Library, China National Knowledge Infrastructure, Wangfang med online, Korean Studies Information Service System, Research Information Sharing Service and Oriental medicine Advanced Searching Integrated System). The search included Korean, English, Chinese reports and there was no limit on the search period. All of randomized controlled clinical trials (RCTs) that used Chuna manual therapy for primary dysmenorrhea were selected. Results 27 RCTs met required condition. Meta-analysis showed positive results for Chuna manual therapy for primary dysmenorrhea in terms of therapeutic effects and reduction of symptom scores compared to west medicine, herbal medicine, acupucture and other treatments. Conclusions Above results showed that performing chuna is effective in treating dysmenorrhea. However, in some studies, there was no statistic significance between the experimental group and the control group. Also, according to Cochrane Risk of Bias (RoB) evaluation method, quality of the studies were not high enough. Since most of the materials were in Chinese, more high-quality clinical trials about Chuna therapy for primary dysmenorrhea are needed in Korea. (J Korean Med Rehabil 2017;27(3):81-93)

5주간의 온천요법 전후 요통의 통증변화에 관한 임상연구

신재화 ( Jae Hwa Shin ),이옥진 ( Yu Chen Li ),최보미 ( Bo Mi Choi ),안택원 ( Taek Won Ahn ),이정민 ( Jung Min Lee ) 한방재활의학과학회 2013 한방재활의학과학회지 Vol.23 No.3

ObjectivesThe aim of this clinical study was to find out the changes of self-reported pain intensity before and after balneothrapy in participants with low back pain. MethodsIn this study 20 participants with low back pain went through 5 weeks of balneothrapy course, once in a week. Each week visual analogue scale (VAS) and pain threshold were measured before and after balneothrapy, which consisted of 30 minutes of high pressure underwater shower (32~36oC) and another 30 minutes of whole body bathing (32~40oC). Results1. The average of VAS significantly decreased from 64.00±16.35 to 34.00±15.69 after 5 weeks of balneothreapy (p<0.001). 2. The average of pain threshold significantly increased from 8.31±2.52 lbf to 9.53±3.11 lbf after 5 weeks of balneothreapy (p<0.05). ConclusionsThe results showed that 5 weeks of balneotherapy had significant effect on alleviating pain in low back pain participants, which means balneothreapy may be used as a complementary treatment on musculoskeletal diseases and other chronic diseases. Further studies are anticipated in the future to find out other various effects of balneothrapy. (J Korean Med Rehab 2013;23(3):133-140) ObjectivesThe aim of this clinical study was to find out the changes of self-reported pain intensity before and after balneothrapy in participants with low back pain. MethodsIn this study 20 participants with low back pain went through 5 weeks of balneothrapy course, once in a week. Each week visual analogue scale (VAS) and pain threshold were measured before and after balneothrapy, which consisted of 30 minutes of high pressure underwater shower (32~36oC) and another 30 minutes of whole body bathing (32~40oC). Results1. The average of VAS significantly decreased from 64.00±16.35 to 34.00±15.69 after 5 weeks of balneothreapy (p<0.001). 2. The average of pain threshold significantly increased from 8.31±2.52 lbf to 9.53±3.11 lbf after 5 weeks of balneothreapy (p<0.05). ConclusionsThe results showed that 5 weeks of balneotherapy had significant effect on alleviating pain in low back pain participants, which means balneothreapy may be used as a complementary treatment on musculoskeletal diseases and other chronic diseases. Further studies are anticipated in the future to find out other various effects of balneothrapy. (J Korean Med Rehab 2013;23(3):133-140)

한약을 중재로 한 골절 동물실험연구에 대한 국내 문헌 분석

최봉석 ( Bong-seok Choi ),구지향 ( Ji-hyang Gu ),하현주 ( Hyun-ju Ha ),이옥진 ( Yu-chen Li ),조동찬 ( Dong-chan Jo ),이은정 ( Eun-jung Lee ),오민석 ( Min-seok Oh ) 대한한의학회 한방재활의학과학회 2018 한방재활의학과학회지 Vol.28 No.3

Objectives The aim of this research is to analyze research trends on fracture animal experimental study in Korea. Methods For reviewing research, we constructed a key question as the effect of herbal medicine on fracture healing and selected fracture animal experimental research. We searched the following 6 databases: KoreaMed, Kmbase, Koreanstudies Information Service System (KISS), National Digital Science Library (NDSL), Korea Institute of Science and Technology Information (KISTI), Oriental Medicine Advanced Searching Integrated System (OASIS). Results A total of 283 potentially relevant studies were identified; only 12 studies were selected for reviewing research. Almost studies showed that herbal medicine had significant effect on fracture healing. Conclusions The research showed that herbal medicine could significantly stimulate fracture healing and reduced inflammation. In the future, more fracture animal experimental study should be actively conducted. (J Korean Med Rehabil 2018;28(3):27-38)

흉추 및 요추 압박골절 환자의 통증 감소에 대한 한의학적 치료 효과

오승준(Seung Joon Oh),조동찬(Dong Chan Jo),이옥진(Yu Chen Li),이은정(Eun Jung Lee) 한의병리학회 2018 동의생리병리학회지 Vol.32 No.4

한방복합치료를 병행한 도인운동요법이 요통환자의 통증 및 기능 개선에 미치는 영향

최봉석(Bong Seok Choi),이은정(Eun Jung Lee),이옥진(Yu Chen Li),이정민(Jung Min Lee),김은석(Eun Seok Kim),송광찬(Gwang Chan Song),정인철(In Chul Jung),오민석(Min Seok Oh) 한의병리학회 2018 동의생리병리학회지 Vol.32 No.1

골반 골절에 한방재활치료를 적용한 증례 보고 및 보존적 치료에 대한 국내 문헌 분석

하현주 ( Hyun Ju Ha ),구지향 ( Ji Hyang Gu ),최봉석 ( Bong Seok Choi ),오태영 ( Tae Young Oh ),오은미 ( Eun Mi Oh ),이옥진 ( Yu-chen Li ),오민석 ( Min-seok Oh ) 대한한의학회 한방재활의학과학회 2018 한방재활의학과학회지 Vol.28 No.2

The objective of this study is to investigate conservative treatment of pelvic fracture, and report that Korean rehabilitation treatment is effective for pelvic fracture. We reported a case about pelvic fracture treated with Korean rehabilitation treatment. We searched 10 domestic electronic databases to find reports on conservative treatment of pelvic fracture. We selected and analyzed 12 studies. In this case, pain, range of motion, and Oswestry Disability Index of patient were improved by Korean rehabilitation treatment. In analysis, traction, pelvic sling, hip spica cast, pelvic belt, medication are used in western medical treatment. Acupuncture, herbal medicine, cupping, moxibustion, physical therapy, manual therapy are used in Korean medical treatment. Most of conservative treatments are effective for pain, bone union, osteoporosis, dysfunction. In this study, we expect further study of Korean rehabilitation treatment program for pelvic fracture to compensate existing conservative treatment. (J Korean Med Rehabil 2018;28(2):135-148)