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온열환경과 인삼(Panax Ginseng)이 Rat의 체온, 혈액학적 변화, 면역반응에 미치는 영향
이서라,이인희,김민지,류재환,Yi, Seo-Ra,Lee, In-Hee,Kim, Min-Ji,Lew, Jae-Hwan 대한한방내과학회 2014 大韓韓方內科學會誌 Vol.35 No.1
Objectives : This study was designed to test the effect of heating condition and Panax ginseng on body temperature, hematologicala changes, and immune response. Methods : The extract from Panax ginseng was made by the pharmacy department of Kyung Hee Oriental Medical Hospital. The animals were divided into four groups; control, room temperature Panax ginseng (G), $28^{\circ}C$ heating, and $28^{\circ}C$ heating Panax ginseng (heating G). Each group has 8 Sprague-Dawley rats. We measured body weight & temperature twice a week. After 2 weeks of experiment, serum lipid level, WBC, differential count, lymphocyte proliferation and immune cytokine concentration were measured. Results : 1. Simultaneous application of heating condition and Panax ginseng induced decreased body weight and increased body temperature. 2. Simultaneous application of heating condition and Panax ginseng induced decreased AST, ALT and BUN. 3. Simultaneous application of heating condition and Panax ginseng tended to decrease TNF-${\alpha}$ concentration, while application of room temperature and Panax ginseng tended to increase TNF-${\alpha}$ concentration. Conclusions : Simultaneous application of heating condition and Panax ginseng decreseas body weight, increases, body temperature and has a tendency to decrease TNF-${\alpha}$ concentration.
온열환경과 부자이중탕(附子理中湯)이 Rat의 면역반응 및 지질대사에 미치는 효과
노현인,윤다래,이서라,이인희,홍성인,류재환,Noh, Hyun-In,Yoon, Da-Rae,Yi, Seo-Ra,Lee, In-Hee,Hong, Sung-In,Ryu, Jae-Hwan 대한한방내과학회 2013 大韓韓方內科學會誌 Vol.34 No.1
Objectives : This study was designed to test the effect of a warm environment and Bujaijung-tang on immune and lipid metabolism in rats. Methods : The extract from Bujaijung-tang was made by the pharmacy department of Kyung-Hee oriental medical hospital. The animals were divided into four groups, by room or warm environment and Bujaijung-tang administration. Each group had 8 Sprague-Dawley Rats. We measured body temperature twice a week, body weight three times a week. After 3 weeks of experiment, serum lipid level, WBC, differential count, lymphocyte proliferation and immune cytokine concentration were measured. Results : 1. warm environment induced weight loss in rats. 2. warm environment induced a decrease of total cholesterol and low-density lipoprotein (LDL) cholesterol gain. 3. warm environment and Bujaijung-tang induced an increase of tumor necrosis factor (TNF)-${\alpha}$ concentration. Conclusions : The warm environment had a hyperlipidemia modulating effect. The warm environment and Bujaijung-tang had an immune modulating effect.
한방병원 중증치료실 입원 환자의 임상적 분석 - 주 질환 및 합병증 위주로 -
노현인,이지숙,윤다래,이서라,류재환,Noh, Hyun-In,Lee, Jee-Sook,Yoon, Da-Rae,Yi, Seo-Ra,Ryu, Jae-Hwan 대한한방내과학회 2012 大韓韓方內科學會誌 Vol.33 No.2
Objectives : This study was designed to quantify the characteristics, main diagnosis and complications in the intensive care unit (ICU) at an Oriental Medical Hospital. Methods : The medical records of 44 patients admitted to the ICU at Kyunghee Oriental Medical Hospital between January 1, 2011 and December 31, 2011 were reviewed. Basic characteristics of patients, admission channel, main diagnosis, east-western medical therapy, mortality, and complications were investigated retrospectively based on medical notes. Results : 1. The total number of patients was 44. Males were 63.6%, females 36.3%. Average admission days was 15.9. 2. The most frequent age group is eighties, 38.6%. 3. The most frequent disease is cerebrovascular disease, 61.3%. 4. The medical therapy done after admission to ICU was intubation. Central vein insertion was performed next, followed by Foley's catheter insertion, ventilator, tracheostomy, nasogastric intubation, and thoracentesis in order. The proportion of Oriental medical treatment provided to the patients of ICU was as follows: herbal medication only 6.8%; herbal medication plus acupuncture 31.8%; herbal medication, acupuncture electro-acupuncture, plus subcutaneous acupuncture 2.3%; and none 27.3%. 5. The number of cases of complications occurred since ICU admission was 18. The most frequently observed complication was infection, including 6 cases of pneumonia and 4 cases of urinary tract infection. Conclusions : We suggest that ICUs of Oriental medical hospitals need to be managed effectively to treat diseases including cerebrovascular disease and prevent complications.
상엽(桑葉)의 고지방식이 유도 비만 쥐에 대한 조직학적 및 혈청학적 항비만 효과 연구
이지숙,노현인,윤다래,이서라,류재환,Lee, Jee-Sook,Noh, Hyun-In,Yoon, Da-Rae,Yi, Seo-Ra,Lew, Jae-Hwan 대한한방내과학회 2012 大韓韓方內科學會誌 Vol.33 No.3
Objectives : Mori Folium is used for hyperlipidemia or diabetes. The study was designed to test the anti-obesity effect of Mori Folium on body weight, hepatic fat accumulation and serum lipid level. Methods : The extract from Mori Folium was made by the pharmacy department of Kyung-hee oriental medical hospital. Normal diet, high-fat diet, 30% reduced diet and Mori Folium groups were set. The normal group was administered normal rat food, but the other three groups were administered high fat food. We measured body weight once a week. After 3 weeks experiment, hepatic lipid accumulations were measured. Also we compared serum lipid levels among the 4 groups after 3 weeks. Results : Mori Folium had no effect on body weight, but the 30% reduced diet had an inhibitory effect on body weight gain. Mori Folium had more inhibitory effect on hepatic fat accumulation than a 30% reduced diet. Mori Folium also has more inhibitory effect on serum triglyceride than 30% reduced diet. Conclusions : Mori Folium has anti-obesity effect on hepatic lipid accumulaion and serum triglyceride level in high fat diet induced rats.
윤다래,이지숙,노현인,이서라,류재환,Yoon, Da-Rae,Lee, Jee-Sook,Noh, Hyun-In,Yi, Seo-Ra,Ryu, Jae-Hwan 대한한방내과학회 2012 大韓韓方內科學會誌 Vol.33 No.2
Objectives : This study was aimed to provide the basic characteristic of patients who visited an Oriental medical hospital emergency room. Methods : We performed a retrospective study on 1,119 patients who visited Kyunghee University Oriental Medical Hospital Emergency Room from June 1, 2011 to March 31, 2012. Results and Conclusions : 1. In distribution of sex, the rate of males was 44.1%, and that of females was 55.9%. The male to female ratio was thus 1:1.26. The patients' average age was 54.64 and the 6th decade of life was the peak age group. 2. Most of the patients visited the Oriental medical hospital emergency room between 11:00 and 23:00. 3. In distribution by days of the week, the most common was Sundays (24.5%), followed by Mondays (16.7%). 4. In the month distribution, the most was December (12.4%), followed by November (10.0%). 5. The patients were grouped as follows: neurological diseases 58.9%, musculoskeletal disease 27.5%, internal medical disease 10.4%, and others 3.2%. 6. Admission rate of patients being treated was 38.8%, and the admission to the intensive care unit (ICU) was 4.5%. of total visiting patients.