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심혈관계의 중추조절에 대한 Prostaglandin $F_{2{\alpha}}$의 영향
이상복,김인순,김옥녀,조규철,Lee, S.B.,Kim, I.S.,Kim, O.N.,Cho, K.C. 대한약리학회 1982 대한약리학잡지 Vol.18 No.1
This study was carried out in order to clarify whether the cardiovascular effect of prostaglandin(PG) $F_{2{\alpha}}$ might be centrally mediated. In unrestrained conscious rat, $PGF_{2{\alpha}}$ was administered into the lateral ventricle. The mechanism of action was also studied by observing the interaction with several adrenergic antagonists injected subcutaneously, Indomethacin was administered into lateral ventricle to investigate the role of endogenous $PGF_{2{\alpha}}$ on the central regulation of cardiovascular system. The results were as follows: 1) The intraventricular injection of $PGF_{2{\alpha}}$ produced an increase in blood pressure and heart rate. 2) The pretreatment with phenoxybenzamine (2 mg/g, s.c.) inhited pressor, but not heart rate responses to the intraventricular injection of $PGF_{2{\alpha}}$ $(2{\mu}g/kg)$. 3) The pretreatment with propranolol (1 mg/kg, s.c.) inhibited tachycardia, but not pressor responses to the intraventricular injection of $PGF_{2{\alpha}}(2{\mu}g/kg)$. 4) The intraventricular injection of indomethacin $(40{\mu}g/kg)$ could not induce significant changes in blood preesure and heart rate. 5) The result indicates that intraventricular injection of $PGF_{2{\alpha}}$ produces pressor and tachycardia responses in the unanesthetized rat, and it is mediated primarily by centrally increased sympathetic outflow. But the endogenous $PGF_{2{\alpha}}$ synthetized in the brain seems to play minor role in the direct regulation of cardiovascular system.
심혈관계의 중추조절에 대한 Prostaglandin F<sub>2α</sub>의 영향
이상복(S.B. Lee),김인순(I.S. Kim),김옥녀(O.N. Kim),조규철(K.C. Cho) 대한약리학회 1982 대한약리학잡지 Vol.18 No.1
This study was carried out in order to clarify whether the cardiovascular effect of prostaglandin(PG) F<sub>2α</sub> might be centrally mediated. In unrestrained conscious rat, PGE<sub>2α</sub> was administered into the lateral ventricle. The mechanism of action was also studied by observing the interaction with several adrenergic antagonists injected subcutaneously, Indomethacin was administered into lateral ventricle to investigate the role of endogenous PGE<sub>2α</sub> on the central regulation of cardiovascular system. The results were as follows: 1) The intraventricular injection of PGE<sub>2α</sub> produced an increase in blood pressure and heart rate. 2) The pretreatment with phenoxybenzamine (2 mg/g, s.c.) inhited pressor, but not heart rate responses to the intraventricular injection of PGE<sub>2α</sub> (2μg/kg). 3) The pretreatment with propranolol (1 mg/kg, s.c.) inhibited tachycardia, but not pressor responses to the intraventricular injection of PGE<sub>2α</sub>(2μg/kg). 4) The intraventricular injection of indomethacin (40μg/kg) could not induce significant changes in blood preesure and heart rate. 5) The result indicates that intraventricular injection of PGE<sub>2α</sub> produces pressor and tachycardia responses in the unanesthetized rat, and it is mediated primarily by centrally increased sympathetic outflow. But the endogenous PGE<sub>2α</sub> synthetized in the brain seems to play minor role in the direct regulation of cardiovascular system.
원통형 입자에 따른 관내 차압 전산 해석 및 Ergun식 보정 연구
유승영(S.Y Yoo),임태규(T.G. Lim),이상복(S.B. Lee),노태성(T.S. Roh) 한국전산유체공학회 2012 한국전산유체공학회 학술대회논문집 Vol.2012 No.5
In this study, Pressure drops in a pipe according to cylinderical particle that has been calculated and analyzed. In general, it is used in a interior ballistic cylindrical particle shape. The analysis of 10 cases for Reynolds number has been conducted in 3 cases cylindrical particle. The results have been compared to the Erguns empirical equation which predicts pressure drop in pipe. To reduce difference between the Erguns empirical equation and the numerical results, calibration has been conducted.
장진성(J.S. Jang),성형건(H.G. Sung),이상복(S.B. Lee),김인주(I.J. Kim),노태성(T.S. Roh),최동환(D.W. Choi) 한국전산유체공학회 2010 한국전산유체공학회 학술대회논문집 Vol.2010 No.5
Using the numerical code for the interior ballistics, the performance of the interior ballistics with the characteristics according to the position of the solid propellant in chamber has been investigated. In existing research, propellants have been evenly distributed in the chamber. In this study, however, several cases of the existence of empty space in the chamber at which the propellants are not evenly distributed are considered. The 7-perforated propellant configuration has been used in this research. The results have shown the change of performance of the interior ballistics according to solid propellant positions in the chamber.
장진성(J.S. Jang),성형건(H.G. Sung),이상복(S.B. Lee),노태성(T.S. Roh) 한국전산유체공학회 2010 한국전산유체공학회지 Vol.15 No.4
Using the numerical code for the interior ballistics, the performance of the interior ballistics with the characteristics according to the position of the solid propellant in chamber has been investigated. In existing research, propellants have been evenly distributed in the chamber. In this study, however, several cases of the existence of empty space in the chamber at which the propellants are not evenly distributed are considered. The 7-perforated propellant configuration has been used in this research. The results have shown the change of performance of the interior ballistics according to solid propellant positions in the chamber.
초지 및 조사료 : 2회 예취 재배법을 이용한 초다수 벼(Oryza sativa L.) 계통의 생육,수량 및 사료가치 평가
백진수 ( J. S. Paek ),이점호 ( J. H. Lee ),정오영 ( O Y. Jeong ),홍하철 ( H. C. Hong ),이규성 ( K. S. Lee ),진일두 ( I. D. Jin ),이상복 ( S. B. Lee ),최용환 ( Y. H. Choi ),양창인 ( C. I. Yang ),김종근 ( J. G. Kim ),김병완 ( B. W. Kim 한국동물자원과학회 ( 구 한국축산학회 ) 2006 한국축산학회지 Vol.48 No.3