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이식된 결합조직 교원막이 초기 접합상피의 근단전이 억제에 미치는 영향에 관한 연구
이규섭,이재현,정진형,Lee, Kyu-Seop,Lee, Jae-Hyung,Chung, Chin-Hyung 대한치주과학회 1993 Journal of Periodontal & Implant Science Vol.23 No.1
After periodontal surgery, the potential healing responses were occurred by interaction among junctional epithelium, gingival connective tissue, alveolar bone and periodontal ligament. The only cell that created periodontal regeneration was derived from periodontal ligament. The aim of the study was to evaluate the regenerative effects of the collagen membrane($collacote^{\circ}C$) and autogenous connective tissure graft with periosteum. Experimental periodontitis were created in furcation area of 4 adult dogs with bone removal and gutta percha packing. After 6 weeks later, the gutta percha was removed and experiment was performed divided by 3 groups. 1) Flap operation(control group). 2) Flap operation with collage membrane(Experimental group I). 3) Flap operation with autogenous connective tissue graft with periosteum (Experimental group II). After dogs were sacrificed after two and three weeks, specimens were prepared and stained with hematoxylin-eosin and masson-trichrome stain for light microscopic study. The results were as follows : 1. In all gruoups, connective tissue compartments were increased from two to three weeks especially in experimental group I. 2. Collagen membrane and connective tissue were increased collagen deposits of periodontal ligament. Therefore collagen fiber attached to tooth surface was seen. 3. In al experimental groups, newly forming alveolar bone was seen. 4. Collagen membrane and connective tissue were which prevented proliferation of epithelium, aided connective tissue new attachment and influenced periodontal regeneration.
이규섭,박재범,송승한,오상하,강낙헌,Lee, Kyu-Seop,Park, Jae Beom,Song, Seung Han,Oh, Sang Ha,Kang, Nak Heon 대한두개안면성형외과학회 2013 Archives of Craniofacial Surgery Vol.14 No.2
Except for special situations, it is generally agreed that best results in the treatment of facial fractures is expected if reduction is done within the first 2 or 3 weeks after injury. We reduced facial bone fractures at 4 to 7 weeks after trauma. A 44-year-old female patient underwent open reduction for her right zygomaticomaxillary complex fracture at 7 weeks after injury. A 59-year-old female patient underwent surgery for the right mandible body and left parasymphysis fractures at 4 weeks after injury. Using traditional approaches, granulation tissue and callus were removed from the fracture sites, and malunited fracture lines were separated by a small osteotome. We reduced the displaced fractured zygoma and mandible to their normal anatomical positions and fixed them using titanium plates. No complications such as asymmetry, malunion, malocclusion, or trismus were seen. Unfavorable asymmetric facial contours were corrected, and we obtained good occlusion with favorable bony alignment. The functional and aesthetic outcomes were satisfactory. Through removal the callus and limited osteotomy, a successful approach to the previously fractured line was possible, and an exact correction with symmetry was obtained. This method can be a good option for obtaining good mobility and clinical results in treating delayed facial bone fractures.
공길용 ( Kong Kil-yong ),김현태 ( Kim Hyun-tae ),이규섭 ( Lee Kyu-seop ),김영호 ( Kim Young-ho ) 한국농공학회 2005 한국농공학회 학술대회초록집 Vol.2005 No.-
In order to construct the farm road in Shi-Hwa project, coarse soils excavated from hillsides have been used as road materials for reclamation. Suitable borrow pits available in land are now limited and also they bring about environmental problems when soils are excavated at the borrow pits and transported to the site. When using fine and wet materials as fill, however, many engineering problems can be encountered. Usually, the materials have high water contents, low strength, and high compressibility. In order to use them, we need research that can improve the inherent properties of those materials. In order to tackle with the problems, researches on soil improvement involve mixing lime geo-cement to the fine wet soils. A lab model test is necessary to verify effectiveness and comparison of those techniques. A field test is also required to show applicability and to find problems that may exist in the design and construction stages.
증례 : 혈액종양 ; 여러 내장에 재발한 다발고립형질세포종 1예
송익찬 ( Ik Chan Song ),백승우 ( Seung Woo Baek ),이규섭 ( Kyu Seop Lee ),윤각원 ( Gak Won Yun ),양영준 ( Young Jun Yang ),김진만 ( Jin Man Kim ),조덕연 ( Deog Yeon Jo ) 대한내과학회 2011 대한내과학회지 Vol.80 No.5
다발고립형질세포종은 고립형질세포종의 약 5%를 차지하는 매우 드문 질환이다. 저자들은 뼈의 다발고립형질세포 종으로 치료받은 후 완전반응 상태를 유지하던 중, 여러 내장기관에 골수외형질세포종의 형태로 재발한 매우 드문 경우의 다발고립형질세포종을 경험하였다. 뼈의 다발고립형질 세포종으로 치료받은 경력이 있는 68세 남자에서 배뇨곤란 및 변비가 발생하였다. 복부 및 골반의 전산화단층촬영에서 위, 췌장, 골반강 및 우측 둔부에 덩이가 발견되었으며, 위의 덩이에 대한 내시경 조직검사에서 형질세포종이 확인되었다. 이 환자는 내원 20개월 전, 우측 제 6 늑골 및 우측 장골의 다발고립형질세포종으로 방사선 치료를 받았고, 내원 14개월 전에는 좌측 제 5, 6, 7, 9 늑골에 재발하여 방사선 치료를 받았으며, 내원 12개월 전에는 제 5경추에 재발하여 방사선 치료 및 VAD 화학요법을 시행 받은 적이 있었다. 골반강의 덩이에 대한 방사선치료와 bortezomib+dexamethaone 화학요법으로 모든 덩이는 소실되었고, 8개월째 재발의 증거 없이 경과관찰 중이다. 향후 다발고립형질세포종의 임상 경과 및 치료와 예후인자에 관한 연구가 필요할 것으로 생각 된다. Multiple solitary plasmacytoma is a very rare disease entity, which occurs in up to 5% of patients with solitary plasmacytomas. We report an atypical case of multiple solitary plasmacytoma that recurred in multiple visceral organs without any evidence of bone marrow involvement. A 68-year-old male presented with voiding difficulty. Twenty months earlier, he had been placed on local radiotherapy for solitary plasmacytomas in the right 6th rib and right iliac bone. Recurrences were noted 14 and 12 months later in several ribs and the 5th cervical vertebra, respectively. These were well controlled with local radiotherapy and conventional systemic chemotherapy. He had multiple soft tissue masses in the stomach, pancreas, pelvic cavity, and right buttock. An endoscopic biopsy of the gastric mass confirmed the diagnosis of plasmacytoma. Local radiotherapy to the pelvic mass and systemic therapy consisting of bortezomib and dexamethasone were given, and he has been well for 8 months.