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시민참여형 해안돌봄 정책 도입방안 연구
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데이터 방송의 연구 동향 분석
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Metabolite Chemical Composition of the Bletilla striata(Thunb.) Reichb. f. Endophyte Penicillium oxalicum
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- 저자 : 윤미경(Mi Kyoung Yoon) (검색결과 3 건)
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유아 다문화 교육이 사회관계에 미치는 효과에 대한 메타분석
황윤세(Yoon-se Hwang),김언진(Eon-jin Kim),김경임(Kyoung-im Kim),윤미경(Mi-kyoung Yoon) 한국열린유아교육학회 2016 열린유아교육연구 Vol.21 No.3
본 연구는 다문화 교육이 사회관계에 미치는 효과를 분석하였다. 분석된 자료는 2001년부터 2015년까지 발행된 25편의 논문으로 다문화 교육이 사회관계에 미치는 효과를 검증한 석·박사 학위 논문과 학술지에 게재된 논문 중 본 연구의 자료 선정기준에 부합하는 논문을 대상으로 하였다. 이들 자료로부터 다문화 교육에서 특성변인에 따라 종속변인인 사회관계 효과에 어느 정도 영향을 미치는지 변인별 평균 효과크기와 변인 간 평균 효과크기의 차이를 밝히는 데에 연구의 목적이 있다. 본 연구의 결론은 다음과 같다. 첫째, 확률효과모형에 의한 효과크기를 산출한 결과 다문화 교육이 사회관계에 미치는 전체 평균 효과 크기는 1.51로서 큰 효과 크기를 나타냈다. 둘째, 다문화 교육이 특성변인별로 사회관계에 미치는 효과크기는 각각 다르게 나타났으며 출간 유형, 출간 시기, 연구 대상 연령에 따른 효과크기는 차이가 있었으나 프로그램 적용 기간, 실험 집단 인원에 따른 효과크기는 큰 차이가 나타나지 않았다. 이러한 결과를 종합하면, 다문화 교육이 사회관계에 미치는 효과에 큰 영향을 미치므로 효과 크기를 고려하여 사회관계 향상을 위한 다문화 교육에 대한 전략 및 도구를 개발 할 필요가 있다. The purpose of this study was to analyze the effects of multi-cultural education on social relationships. We conducted a literature review and meta-analysis, using the data of previous effort papers, to confirm the effects of multi-cultural education on social relationships. Twenty-five papers, comprising Master``s or PhD theses or peer-reviewed articles that had been published from 2001 to 2015, were chosen to meet the selection criteria for acceptance for publication in the review journal. In terms of variables that affect society, the study aimed to identify the difference between the aver age effect size among variables such as relaxation, which is a dependent variable of multi-cultural education. There sults demonstrated that, first, the magnitude of impact due to the effect of the probabilistic model calculation infant was as follows: the over all multi-cultural education demonstrated a large average effect size of 1.51 on social relationships. Second, the magnitude of impact on creativity was found to differ depending on region. These results have been newly discovered through re-interpretation of the development of the program using multi-cultural education. However, a support system for the existing education system and teaching methods for post-modern social relationships are required.
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폴리락티드 - 글리콜리드 마이크로피어에 봉입된 단백질의 항원성 평가
송세현(Seh Hyon Song),조성완(Seong Wan Cho),신택환(Taek Hwan Shin),윤미경(Mi Kyoung Yoon),최영욱(Young Wook Choi) 한국약제학회 2001 Journal of Pharmaceutical Investigation Vol.31 No.3
N/A Biodegradable polymeric microspheres were studied for their usefulness as carriers for the delivery of vaccine antigens. However, protein antigen could be denatured during microencapsulation processes due to the exposure to the organic phase and stress condition of cavitation and shear force. Therefore this study was carried out to re-evaluate the degree of protein denaturation during microencapsulation with poly(lactide-co-glycolide) (PLGA) copolymer. PLGA microspheres containing ovalbumin (OVA), prepared by W/O/W multiple emulsification method, were suspended in pH 7.4 PBS and incubated with shaking at 37.5℃. Drug released medium was collected periodically and analyzed for protein contents by micro-BCA protein assay. In order to evaluate the protein integrity, release medium was subjected to the analyses of SDSPAGE and size exclusion chromatography (SEC). And enzyme-linked immunosorbent assay (ELISA) was introduced to measure the immunoreactivity of entrapped OVA and to get an insight into the three-dimensional structure of epitope. The structures of entrapped protein were not affected significantly by the results of SDS-PAGE and SEC. However, immunoreactivity of released antigen was varied, revealing the possibility of protein denaturation in some microspheres when it was evaluate by ELISA method. Therefore, in order to express the degree of protein denaturation, antigenicity ratio (AR) was obtained as follows: amount of immunoreactivity of OVA/total amount of OVA released × 100(%). ELISA method was an efficient tool to detect a protein denaturation during microencapsulation and the comparison of AR values resulted in more accurate evaluation for immunoreactivity of entrapped protein.
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생분해성 폴리락티드/글리콜리드 미립구를 이용한 재조합 소 성장호르몬(rBST)의 지속성주사제 설계
전홍렬,이봉상,권도우,윤미경,전현주,신택환,최영욱 한국약제학회 2002 Journal of Pharmaceutical Investigation Vol.32 No.3
In order to develope a sustained release formulation of bovine somatotropin(BST), which has been used to increase the body weight of oxen or the milk production of dairy cows, poly(D,L-lactide-co-glyceride)(PLGA) microspheres were made by W/O/W multiple emulsification method and solvent extraction method. Physical properties including particle size, drug entrapment, drug release, protein denaturation, and in vivo body weight increase in rats were characterized. The size of the microspheres was increased as the molecular weight of PLGA increased. When Span 65 and stearic acid during preparation were added, the size was decreased but the amount of surface protein was increased, resulting in a high loading efficiency, with fast release of BST from the microspheres. Aggregation of fragmentation of BST by SDS-PAGE during microspheres preparation and drug release study was not observed. Body weight of Sprague-Dawley's male rats was significantly increased after subcutaneous administrations of BST-loaded PLGA microspheres. There was a good correlation between in vivo weight gain and vitro release rate of microspheres. PLGA microspheres with a high surface protein ratio could be a good candidate for the sustained delivery of BST.
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