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흰쥐의 Carbon tetra chloride 급성중독에 따른 혈청성분의 생화학적 변화에 관한 연구
윤기은 ( Yoon Ki Eun ),이경배 ( Lee Kyoung Bae ) 대한임상검사과학회 1975 대한임상검사과학회지(KJCLS) Vol.7 No.1
The authors studied on the Biochemical changes of the rat, after 0.5ml of carbon tetra chloride Subcutanecous injection, the intervals of 6, 12hrs 1, 2, 3, 5, and 7 days, after the injection, the animals were sacrificed respectively. The results were as follows: The Biochemistrical change in the blood serum are most prominent in 2 day group. (Glucose: ♂137mg/dl ♀ 132mg/dl Creatinine: ♂ 1. 6mg/dl, ♀ 1. 2mg/dl uric acid: ♂ 4.5mg /dl, ♀ 4.4mg/dl urea nitrogen: ♂ 9.8mg/dl, ♀ 9.5mg/dl)
검체보존(檢體保存) 온도(溫度) 및 시간(時間)에 따른 Serum phosphatase 활성도(活性度) 변화(變化)에 관(關)한 연구(硏究)
김종호 ( Chong Ho Kim ),윤기은 ( Ki Eun Yoon ) 대한임상검사과학회 1981 대한임상검사과학회지(KJCLS) Vol.13 No.1
The authors studied on the variations of serum phosphatase activities in the preservative periods and temperatures, the results were obtained as follows. 1. The serafor determination of ALP and ACP must be stored in a refrigerator. 2. As the time progressed, the activities of ALP showed a slight increase, but those of ACP showed a rapid decrease. 3. After the collection, the activities of prostatic ACP showed the decreased rate, 14.7%, within 30 minutes , and the decreased rate, 52.5% , within an hour at room temperature, but the decreased rate, 5.8% withion 30 minutes and 12.5% , within an hour in a refrigerator. 4. The activities of ALP showed the increased rate, 8.5%, for six hours in the refrigerator but the increased rate, 19.4% , at the room temperature.
한국인(韓國人)의 간염(肝炎) B virus 항원(抗原)(HBsAg) 양성율(陽性率)에 대(對)한 조사(調査)
문희주 ( Hi Joo Moon ),윤기은 ( Ki Eun Yoon ),김경희 ( Kyung Hi Kim ),이장훈 ( Jang Hoon Lee ) 대한임상검사과학회 1979 대한임상검사과학회지(KJCLS) Vol.11 No.1
A study on the positive rate of HBs Ag. among the donors who are in the prime of life in Korea which may be one of the most prevailing area of hepatitis in the world, was conducted from April 1st, 1977 to March 31st, 1979 for two years by Seoul Red Cross Blood Service and its branch organs. The subjects of the research are 80.250 persons who donated their serum to above institute and organs through out the country, and the resultsare as follows: 1. The number of 3,164 from 80,250 persons proved to be positive, showing 3. 94%, and the rateof the male was indicated 1. 41% higher than of the female as the former marked 4. 42% while the latter 3.01%. 2. The positive rate by the year represents that it was 3.44% in 1977 and 4.36% in 1978, indicating an increasing rate of 0.92% as a result. 3. The seasonalc hange is that it shows aneye opening 4. 36% in summer (June, July and August), 4.01% in winter December, January and February), 3.74% in autumn(September, October and November), 3.61% in spring (March, April and May) on the overage. 4. The positive rate by the age group appears as follows; The highest rate group is that of 16 to 20 years, marking 4. 63% and the next is 21-25 (3.51%), those over 36 (2.83%), 26-30 (1.89) and the group of 31-35(1.41%) records the minimum rate of all. 5. The positve rate by occupations is that the top class is on the staffs of firms. representing 5.10%. and the order of the rest is students (5.02%), the others (2.55%), the unemployed (4.41%) and merchants (0.47%). 6. The distribution by the types of blood , A (4.02%) , B(3.96%) AB(4. 30%) , and 0(3.69%) is similar on the whole, and the remarkable disparity among the types is not found. 7. The overage rate of blood donating persons in Korea is much higher than that of the U.S.A (0.1%), Nonvay (0.16%), France (0.4%), Italy (1.6%) and Japan (2.0%).
혈액의 pH와 PCO2, HCO3, dissolved CO2, total CO2의 비교
김종호 ( Chong Ho Kim ),신용섭 ( Yong Sub Shin ),윤기은 ( Ki Eun Yoon ) 대한임상검사과학회 2000 대한임상검사과학회지(KJCLS) Vol.32 No.3
We detennined the blood pH, partial carbondioxide pressure(PC02), concentration of bicarbonate ion(HC03 ), dissolved CO2 with H2C03(DSC02), and concentration of total carbonedioxide(ctC02)of 214 patients in hospital. The patients with pH 7.35-7.45 were classified as the reference group, with pH less than pH 7.35 were classified as the acidosis group, and with pH higher than pH 7.45 were classified as the alkalosis group. Wecompared the distribution, mean value and variation of PC02, HC03, DSC02, ctC02. between each group. πle disσibution of PC02(SDI6.87) in the acidosis group, and HC03 -(SD, 17.219) and ctC02(SD, 19.335) in alkalosis groap showed the largest value in the three groups. The reference patients group showed the smallest distribution of PC02(SD, 8.436), HC03(SD, 5.392), ctC02.(SD, 5.612) in the groups. The acidosis group showed the highest average value of PC02 and DSC02, but the alkalosis group showed the lowest average value of PC02, DSC02. The average value of HC03 and ctC02 showed the highest value in the alkalosis group, but lowest in the acidosis group. The variation rates of the mean of PC02, HC03, DSC02, ctC02 in the acidosis group and alkalosis group, relative to the means of the reference group, were calculated. The acidosis group showed ar increasing variation of PC02 and DSC02, but decreasing variation of HC03 and ctC02. The alkalosis group showed increasing variation of HC03 and ctC02, but decreasing variation of PC02 and DSC02.
Ascorbic acid가 혈청 Fructosamin 측정에 미치는 영향
윤기은,박정오 서울保健大學 1993 論文集 Vol.13 No.1
We have studied by nitroblue tetrazolium reduction applying to Hitachi-7150 autoanalyzer and manual method. The obtained reault were Summerized as follows : The effects of ascorbic acid concentration of 5×1^(-3)mM per liter were not influenced. but, the concentration of fructosamine were increasing influenced for the ascobic acid concentration from 5×10^(-3) to 1×10^(-1)mM per liter. On the other hand, concentration of serum fructosamine could not measured because of the ascorbic acid concentration is over a high range of 2×10^(-1)mM per liter. It is thought that the conclusion as for ascorbic acid in serum fructosamine was interference factor and will be mentioned.