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RISS 인기검색어
- 검색키워드
- 저자 : 유옥철 ( Ok Cheol Yu ) (검색결과 2 건)
- 무료
- 기관 내 무료
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유옥철 ( Ok Cheol Yu ),최성률 ( Sung Ryul Choi ),주환수 ( Hwan Soo Joo ),한창 ( Chang Han ),문혜연 ( Hye Yeon Moon ),정화진 ( Hwa Jin Jung ),정찬헌 ( Chan Hun Jung ) 대한본초학회 2018 大韓本草學會誌 Vol.33 No.6
Objectives : It is necessary to manage herbal medicines based on effectiveness by comparing the efficacy of herbal medicines by region. In this study, we compared anti-oxidative activity and marker compounds of Eucommiae Cortex by regional groups. Methods : Eucommiae Cortex grown and harvested in Gangjin, Sancheong, Yeongwol, Jangsu, and Jecheon were used. Eucommiae Cortex was extracted in distilled water at 100℃ for 3 hours, and filtered. filtered. Extract samples were freeze-dried at -80℃. Comparison of anti-oxidant activity in Eucommiae Cortex samples from regional groups was measured in 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging, 2,2'-azino-bis(3-ethylbenzothiazoline- 6-sulphonic acid) (ABTS) free radical scavenging, and ferric reducing antioxidant power (FRAP) between regional groups of Eucommiae Cortex. In addition, high-performance liquid chromatography (HPLC) analysis was conducted to compare pinoresinol diglucoside concentration by regional groups. Results : HPLC analysis found that pinoresinol diglucoside concentration, widely known as the marker compound of Eucommiae Cortex, was the highest in Gangwon Yeongwol. There was a significant difference in anti-oxidative activity of Eucommiae Cortex between regional groups as discovered in DPPH, ABTS and FRAP assays. DPPH free radical scavenging was the highest in Jeonbuk Jangsu. ABTS free radical scavenging was the highest in Jeonbuk Jangsu and Chungbuck Jecheon. FRAP was the highest in Jeonbuk Jangsu. Conclusions : Although pinoresinol diglucoside concentration was high, anti-oxidative activity was not proportionately high. Pinoresinol diglucoside concentration was the highest in Gangwon Yeongwol. Anti-oxidative activity was the highest in Jeonbuk Jangsu.
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주환수 ( Hwan Soo Joo ),유옥철 ( Ok Cheol Yu ),한창 ( Chang Han ),양규진 ( Kyu Jin Yang ),이성엽 ( Sung Yub Lee ),문혜연 ( Hye Yeon Moon ) 대한한방신경정신과학회 2017 동의신경정신과학회지 Vol.28 No.3
Objectives: The purpose of this study is to review experimental studies of Parkinson`s Disease in Korean medical journals, which have been published since 1990. Methods: Experimental studies related to Parkinson`s disease published in Korean medical journals, registered with Korea research foundation, were searched. Articles were grouped into journal of publication, subject, and publication year. Experimental study subjects and models were analysed. Results and Conclusions: Twenty-two articles about experimental studies of Parkinson`s Disease in Korean medical journals were included in our review. There were 13 articles in which herbs were used for treatment, 4 articles in which bee venom was used for treatment, 4 articles in which acupuncture was used for treatment, and 1 article in which pharmacopuncture was used for treatment. Most of the studies used experimental models of MPTP-induced Parkinson`s disease and MTT assay was used to analyse cell toxicity and cell viability. Pole test, rotarod test, Morris water maze test, and forced swimming test were commonly used to analyse MPTP-induced behavioral deficits in animals. Analysis on experimental studies of Parkinson`s disease was categorized into the subjects of dopaminergic cell protective effect, cell-apoptosis protectiveness, anti-inflammatory effect, and anti-oxidative effect.
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