http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
갑상선 초음파 의료영상을 이용한 정량분석 소프트웨어 개발과 양성 결절 환자에서의 임상 적용
유영재 ( Young Jae Ryu ),허영회 ( Young Hoe Hur ),권성영 ( Seong Young Kwon ),채일석 ( Il-seok Chae ),김민중 ( Min Jung Kim ),김태훈 ( Tae-hoon Kim ) 한국정보처리학회 2021 한국정보처리학회 학술대회논문집 Vol.28 No.2
갑상선 결절(thyroid nodule)은 검진 인구에서 빈번하게 진단되는 질환이지만 현재까지 진단방법은 경험적이며 정성적 판단에 의존하고 있는 실정이다. 본 연구는 갑상선 결절을 평가하기 위하여 시행한 초음파 의료영상을 이용하여 정량 분석할 수 있는 소프트웨어를 개발하였으며 갑상선 양성 결절 환자에서의 임상활용 가능성을 평가하고자 한다. 임상 연구는 총 13명의 갑상선 양성 결절 환자를 대상으로 하였다. 환자별 갑상선 초음파영상을 이용하여 정상부위와 병변부위에서 정량 지표인 변동 계수를 각각 측정하였다. 환자별 정상부위와 병변부위의 변동계수 차이는 대응표본 T 검정을 사용하여 비교하였으며 유의한 차이를 확인할 수 있었다. 본 연구를 통하여 개발한 정량분석 소프트웨어를 실제 갑상선 양성 결절 환자에서 갑상선 결절을 분석·평가하는데 활용할 수 있을 것으로 판단된다.
양측 액와 유방 접근 내시경 갑상선 절제술에 대한 5년간의 분석
박윤철(Yun Chul Park),유영재(Young Jae Ryu),조진성(Jin Seong Cho),윤정한(Jung Han Yoon),박민호(Min Ho Park) 대한갑상선-내분비외과학회 2015 The Koreran journal of Endocrine Surgery Vol.15 No.2
Purpose: We investigated the efficacy and safety of endoscopic thyroidectomy using bilateral axillo-breast approach (BABA) by analyzing short term surgical outcomes. Methods: We retrospectively evaluated 355 patients who underwent BABA endoscopic thyroidectomy between August 2006 and December 2011 at Chonnam National University Hospital and Hwasun Chonnam National University Hospital. The age, sex, clinical and pathologic characteristics of tumors, extent of operation, conversion rate to open thyroidectomy, operation time, hospital stay, thyroglobulin levels after thyroidectomy, recurrence, and complications were analyzed retrospectively. Results: The mean age of the patients was 35 years. The 355 patients comprised 345 females (97.2%) and 10 males (2.8%). The benign tumor was 37 cases (10.4%) and the malignant tumor was 318 cases (89.6%). 28 patients (75.7%) of the benign tumor underwent lobectomy. In malignant tumor, 159 patients (50.0%) underwent lobectomy and 152 patients (47.8%) underwent total thyroidectomy. Mean operation time was 121.1±49.9 minutes, and mean hospital days were 3.4±1.1 days. 21 (6.0%) transient hypocalcemia and 7 (2.0%) permanent hypocalcemia were occurred. The transient voice change occurred in 5 patients (1.4%), but nobody suffered from the permanent recurrent laryngeal nerve injury. 4 patients of recurrent (1.3%) papillary thyroid carcinoma were treated by surgery. Conclusion: Compare to open thyroidectomy with long term follow up studies, BABA endoscopic thyroidectomy is a useful treatment option for both benign and malignant thyroid tumor.
갑상선유두상암의 중앙림프절 전이율에 따른 N1a병기의 세분화
이민완(Min Wan Lee),조진성(Jin Seong Cho),조동훈(Dong Hoon Cho),유영재(Young Jae Ryu),박민호(Min Ho Park),윤정한(Jung Han Yoon) 대한두경부종양학회 2016 대한두경부 종양학회지 Vol.32 No.1
Background : The 2015 American thyroid association (ATA) guidelines greatly expanded section on risk strat-ification of thyroid cancer. Definition of "Low risk of recurrence" has expanded, by inclusion of small volume lymph node involvement, such as less than 5 lymph node metastases each smaller than 2mm in central compartment. Purpose : We evaluated the number of positive nodes, Positive node ratio (PNR), recurrence, and radioablation therapy. Also, evaluated the safety of omitting strategy of radioablation after total thyroidectomy with PTC, espe-cially on low-PNR N1a patients compared with high-PNR N1a patients. Methods : Consecutive 147 N1a and 216 N0 patients who underwent total thyroidectomy with central neck dissection between 2003 and 2004 were enrolled. We divided 147 N1a patients into two groups, such as 96 high-PNR versus 51 low-PNR group according to 50% of PNR, and compared these two groups with N0 group. Results: 7.2% (26/363) recurrences were occurred, and 21/147 (14.3 %) recurrences were on N1a patients, and 5/216 (2.3 %) were on N0 patients. Of these 21 recurrences in N1a stage patients, 20 (95.2 %) recurrences were occurred in high-PNR N1a group and only 1 (4.8 %) recurrence was in low-PNR N1a group. The recurrence of low-PNR N1a group was significantly lower than high-PNR N1a group (Log-rank p value = 0.003), but sig-nificantly not different from N0 group (Log-rank p value = 0.889). Although this study was a retrospective non-randomized trial with small number of patients, the 10-year recurrence of omitting RAI in low-PNR N1a patients with less than 50% of PNR were shown to be comparable with 216 N0 low risk patients. Conclusion : Positive node ratio could be a useful predictor of recurrence and useful guidance postoperative management -rather than absolute number of positive node.