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초음파 유화술시 발생하는 유리기에 대한 아스코르빈산의 각막 내피 보호 효과
서영우,오청훈,김효명,Young-Woo Suh,Chung-Hoon Oh,Hyo-Myung Kim 대한안과학회 2005 대한안과학회지 Vol.46 No.3
Purpose: To evaluate corneal endothelial protection effect of ascorbic acid (AA) at the most appropriate concentration, and determine the synergistic effect of glutathione in irrigation solution during phacoemulsification. Methods: Phacoemulsification was performed in the anterior chamber of 30 rabbit eyes for 5 minutes without damage to other ocular structures. Thirty rabbit eyes were divided into 6 groups, of 5 eyes each, according to the following irrigation solutions in phacoemulsification.: BSS? in group 1, BSS? with 1 mM AA in group 2, BSS Plus? in group 3, BSS Plus? with 0.1 mM AA in group 4, BSS Plus? with 1 mM AA in group 5 and BSS Plus? with 10 mM AA in group 6. Corneal endothelial loss was measured with specular microscopic photographies taken before and 1 week after surgery. Results: Postoperatively endothelial counts were reduced by 592.0±100.0, 275.9±51.9, 658.2±107.1, 466.3±88.6, 259.3±61.6 and 451.6±63.7 (mean cells/mm2±SD) in groups 1-6, respectively. Endothelial cells in group 2 were less reduced than in group 1 (P=0.009), but there was no difference between groups 2 and 5. Though the reduction of endothelial cells in groups 4, 5, and 6 were less than in group 3 (P<0.05), group 5 showed more significant endothelial protection effect than groups 4 and 6 (P=0.009, 0.009). Conclusions: AA in irrigation solution showed endothelial protection effect against free radicals during phacoemulsification, and 1 mM was the most effective concentration. Combination of glutathione with AA did not show any synergistic endothelial protection effect.
중등도 근시환자의 엑시머레이저각막절제술 후 술 전 자료가 없는 경우 인공수정체 도수계산
조희준,오청훈,구오섭,Hee-Jun Cho,Chung-Hoon Oh,O-Sub Koo 대한안과학회 2005 대한안과학회지 Vol.46 No.4
Purpose: To evaluate the correlation between the conventional method and the clinical history method for intraocular lens power calculation for cataract surgery in eyes with previous photorefractive keratectomy in the absence of pre-PRK data. Methods: The medical records of 38 eyes in 23 patients who had been treated with PRK for myopia and were followed up for more than 1 year were reviewed. The IOL powers by conventional method using post-PRK keratometric value and by clinical history method were compared. Results: The mean values of IOL powers by conventional method, and by clinical history method were +20.58±1.10D (range, +16.37~+22.80D) and +21.06±0.85D (range, +18.85~+22.8D), respectively. The following equation describes the regular relationship between the two methods: IOLCHM (clinical history method)= 0.683*IOLCM (conventional method) +7.005 (r=0.878, p<.01). When the IOL powers by conventional method were applied to this equation, the mean difference of value between the IOL powers calculated from this equation and those of the clinical history method was?0.01±0.41D (range, -0.99~+0.76D). Conclusions: This equation will be helpful to calculate the IOL power for cataract surgery in eyes with previous PRK in the absence of pre-PRK data.
증례보고 : 카테콜아민에 의한 심근병증과 울혈성 심부전이 동반된 갈색세포종 환자의 마취경험
최은미 ( Eun Mi Choi ),박청훈 ( Chung Hoon Park ),홍승범 ( Seung Bum Hong ),나성원 ( Sung Won Na ),오영준 ( Young Jun Oh ) 대한마취과학회 2009 Korean Journal of Anesthesiology Vol.56 No.5
Catecholamine-induced cardiomyopathy associated with pheochromocytoma is a relatively well-recognized but rare entity. We report a case of 15-year old man with a pheochromocytoma and severe heart failure caused by a catecholamine-induced cardiomyopathy. He had symptoms such as fatigue, cold sweating, and dyspnea for 7 months. The chest x-ray showed an enlarged cardiac shadow and pulmonary edema. Echocardiography showed severe decreased left ventricular contractility with multiple thrombi and right ventricular hypokinesia with mild pulmonary hypertension. This report describes our experience of the anesthetic management for the removal of pheochromocytoma with catecholamine-induced cardiomyopathy, which barely responded to high vasopressin and epinephrine. (Korean J Anesthesiol 2009;56:601~4)