만성전부포도막염의 시신경유두 신생혈관

안민(Min Ahn),김현숙(Hyeon Sook Kim),조남천(Nam Chun Cho),한홍주(Hong Joo Han) 대한안과학회 1995 대한안과학회지 Vol.36 No.7

외경동맥 안동맥 문합이 발달한 다가야스병 ( Takayasu`s Arteritis ) 2예

조남천(Nam Chun Cho),한홍주(Hong Joo Han),안민(Min Ahn) 대한안과학회 1996 대한안과학회지 Vol.37 No.5

눈물주머니조영술에서 정상을 보이는 눈물흘림 환자의 실리콘관 삽입술 결과

정혜욱,조남천,안민,Hye Wook Jeong,Nam Chun Cho,Min Ahn 대한안과학회 2008 대한안과학회지 Vol.49 No.5

Purpose: To Compare treatment results on silicone tube insertion according to the region and severity of resistance in lacrimal probing for functional nasolacrimal duct obstruction patients who complained of epiphora but are shown to be normal in lacrimal syringing and dacryocystography. Methods: A retrospective study was conducted with 40 subjects (42 eyes) who had silicone tube insertion because of functional nasolacrimal duct obstruction. A comparison was made of post-operational patient satisfaction by grading (0~3) according to the region and the severity of resistance and whether the resistance region was singular or multiple resistance regions were found on probing. Success was defined as a grade of more than one point. Results: Two eyes had no resistance regions, 28 eyes had one resistance region, and 12 eyes had more than two resistance regions on lacrimal probing. There was no statistical significance in the ranking of post-operative satisfaction among theses groups. There was also no difference among the groups for post-operative satisfaction according to obstruction site. Conclusions: Most functional nasolacrimal duct obstruction patients showed partial obstruction of the nasolacrimal duct on probing. Since functional nasolacrimal duct obstruction is not possible, we must treat patients for partial nasolacrimal duct obstruction, for wihch silicone tube insertion is thought to be effective.

망막중심정맥폐쇄에서 방사상시신경절개 후 망막맥락막 곁순환의 형성

서희춘,조남천,안민,권의용,Hee Chun Seo,Nam Chun Cho,Min Ahn,Eui-Yong Kweon 대한안과학회 2008 대한안과학회지 Vol.49 No.3

상안검에 발생한 원발성 점액샘암종 1예

서희춘,안민,조남천,이동욱,Hee Chun Seo,Min Ahn,Nam Chun Cho,Dong Ouk Lee 대한안과학회 2007 대한안과학회지 Vol.48 No.4

Purpose: We report a case of a recurrent, non-tender mass on the right upper eyelid, which was completely excised and histologically diagnosed as mucinous adenocarcinoma from the eccrine gland. Methods: A 67-year-old man presented with a non-tender subcutaneous mass on the right upper eyelid, which had developed 6 months prior to presentation. A similar eyelid mass had also been removed one year earlier. We surgically removed some skin and the mass and conducted a biopsy. During the operation, the biopsy revealed it to be mucinous adenocarcinomas, and thus it was removed by Mohs?? excision technique with a clean margin. Results: A mucinous adenocarcinoma from the eccrine gland was diagnosed by a histologic examination of the removed mass. A whole-body examination was conducted to determine if the lesion was primary or metastatic, and the results indicated it was primary lesion. There was no evidence of other malignant lesions, and a 21-month follow-up is currently being conducted in case of recurrence. Conclusions: Primary mucinous adenocarcinoma occuring on an eyelids is a very rare malignant tumor. Complete mass removal is well known to be the best treatment. For differential diagnosis, various examinations of the entire body are required in case the lesion had metastasized from the breast, gastrointestinal tract, kidneys, ovaries, lacrimal glands and so on. Periodical postoperative examinations must be thoroughly performed, since the probability of recurrence is about 30%.

재발성 보크트-고야나기-하라다 증후군에 대한 임상 분석

김민정,조남천,안민,Min Jung Kim,Nam Chun Cho,Min Ahn 대한안과학회 2006 대한안과학회지 Vol.47 No.2

Purpose: We analyzed the clinical features of patients with recurrent Vogt-Koyanagi-Harada(VKH) syndrome. Methods: A retrospective chart review of 21 patients diagnosed with VKH syndrome between 1994 and 2004 was performed. We grouped the patients into two groups according to the duration of ocular inflammation. Group A included patients with recurrent ocular inflammation lasting 24 months or longer and Group B included those with a duration of less than 24 months. We compared the clinical manifestations, responses to treatment and complications. Results: Group A had 7 patients and Group B had 14 patients. There were significant differences in initial visual acuity, the interval between ocular symptoms and treatment, total steroid dose, and complications. The average final visual acuity of Group A was 0.572 (0.2-1.0), which was relatively favorable. Conclusions: The initial visual acuity and the interval between ocular symptoms and treatment seemed to be important predictors. We conclude that aggressive treatment is necessary in recurrent VKH syndrome, as visual prognosis was relatively favorable despite the cost of the problems associated with high dose steroids and ocular complications.

공막 봉합 인공수정체 삽입술시 병행한 유리체 절제술의 의의

장보현,안민,이동욱,조남천,Bo-Hyun Jang,Min Ahn,Dong-Wook Lee,Nam-Chun Cho 대한안과학회 2005 대한안과학회지 Vol.46 No.3

Purpose: To evaluate the role of vitrectomy in transscleral fixation of posterior chamber intraocular lens (IOL) compared to scleral fixation without vitrectomy. Methods: We reviewed the medical records of 8 eyes which had undergone transscleral fixation with vitrectomy using the three-port-system and 13 eyes which had undergone transscleral fixation only. The postoperative visual acuity, best-corrected visual acuity and changes in astigmatism were compared between the groups. Results: Postoperative uncorrected and best corrected visual acuities were 0.68 and 0.8 in the vitrectomy group and 0.48 and 0.63 in the non-vitrectomy group, respectively. Changes in the amount of astigmatism were significantly less in the vitrectomy group (0.38 diopter) compared to those of the non-vitrectomy group (1.67 diopter). Conclusions: Transscleral fixation of IOL along with three-port-system vitrectomy resulted in good vision with a smaller degree of astigmatism. Adopting three-port-system vitrectomy seems to have caused the good results, because more complete removal of the lens and capsule remnants and adequate maintenance of IOP with accurate needling and IOL positioning was possible using the system.

감염성 안질환의 원인균 및 항생제 감수성에 대한 10년간의 고찰

최현태,이동욱,안민,조남천,유인천,Hyun Tae Choi,Dong-Wook Lee,Min Ahn,Nam Chun Cho,In Cheon You 대한안과학회 2012 대한안과학회지 Vol.53 No.7

Purpose: To investigate the ocular regional incidence, causative species and antibiotic susceptibility in patients with infectious ocular disease whose causative organism was isolated. Methods: A total of 519 eyes in 519 patients with infectious ocular disease, who were diagnosed by smears and cultures from January 2000 to December 2009 were retrospectively reviewed. Results: The mean age of the 519 patients was 54.0 years, and 66.1% of the patients were male. The most common systemic disease was diabetes mellitus. The most common previous ocular disease was keratoconjunctivitis. Specimens were most frequently swabbed from the cornea, where 81.2% were bacteria isolates and 18.8% fungi isolates. The most prevalent causative organism was Staphylococcus epidermidis, and the most prevalent fungus was Fusarium species. Vancomycin, ceftazidime, and fourth-generation fluoroquinolone maintained high antibiotic susceptibility. Methicillin-resistant Staphylococcus aureus and methicillin-resistant Staphylococcus epidermidis were increasing near the end of the reference period, and endophthalmitis was more common in methicillin-resistant Staphylococcus. Conclusions: Identifying the causative organism in infectious ocular disease by smears and cultures is essential. More effective treatment of infectious ocular disease would be possible by analyzing the frequent organism, clinical manifestations, and antibiotic susceptibility. More caution is necessary due to the increase in methicillin-resistant Staphylococcus. J Korean Ophthalmol Soc 2012;53(7):934-940

진균각막염의 임상양상 및 예후 : 20년간의 변화 분석

조상일(Sang Il Cho),박영명(Young Myoung Park),안민(Min Ahn)조남천(Nam Chun Cho),유인천(In Cheon You) 대한안과학회 2021 대한안과학회지 Vol.62 No.7

목적: 최근 20년간 국내에서 발생된 진균각막염 환자의 임상양상, 원인균, 치료, 예후 등의 변화에 대해 알아보고자 하였다. 대상과 방법: 본원에서 각막염으로 진단받고 시행한 각막찰과 및 배양검사에서 진균이 검출된 177안의 의무기록을 후향적으로 조사하였다. 성별, 연령, 선행 요인, 원인균, 임상양상, 치료 방법, 예후 등을 분석하였다. 또한 배양과 KOH염색 여부에 따라 KOH양성그룹, 배양양성그룹, KOH-배양동시양성그룹으로 나누어 조사하였다. 불량한 임상결과와 관련 있는 위험인자를 로지스틱 회귀분석으로 조사하였다. 결과: 대상 환자의 평균연령은 67.4 ± 11.3세였고, 남자가 107명(60.5%)이었다. 진균각막염 발생의 위험인자는 안외상(57.6%), 특히 식물에 의한 외상(29.4%)이 많았다. 가장 흔한 사상진균은 푸사륨 49균주(31.6%)였고 효모균은 칸디다 17균주(11.0%)였다. 진균과 세균이 함께 배양된 41안 중 사상진균과 그람양성균이 29안(70.7%)으로 많았다. 치료 후 시력이 호전된 경우는 KOH양성그룹이 19명(79.2%), 악화된 경우는 배양양성그룹이 36명(40.4%)으로 흔하였다. 다변량분석에서 불량한 임상결과의 위험인자는 이전의 안질환(odds ratio [OR]: 3.744, p=0.010), 전방축농(OR: 2.941, p=0.030), 수술적 치료를 받은 경우(OR: 24.482, p<0.001)였다. 결론: 진균각막염은 KOH만 양성이면 임상양상이 양호하였고, 배양에서 균이 확인되면 심하였다. 진균이 의심되면 초기에 KOH염색과배양검사를 해야 하고, 불량한 임상결과의 위험인자가 있을 경우 조기에 최대한 약물치료를 시행해야 한다. Purpose: To describe the clinical manifestations, causative organisms, treatment, and prognostic factors of fungal keratitis based on analysis of patients over the past 20 years. Methods: A total of 177 patients (177 eyes) with fungal keratitis, who were diagnosed by smears and cultures, were reviewed retrospectively. Sex, age, predisposing factors, causative organisms, clinical manifestations, treatment, and prognosis were evaluated. The patients were divided into three groups: only potassium hydroxide (KOH)-positive, only culture-positive, and KOH- and culture-positive. Logistic regression was performed to identify the factors associated with a poor clinical outcome. Results: The mean age of the patients was 67.4 ± 11.3 years; 107 (60.5%) patients were men. The most common predisposing factor was ocular trauma (57.6%), especially by plants (29.4%). The most prevalent filamentous fungi were Fusarium species (31.6%, 49 isolates), and the most prevalent yeasts were Candida species (11.0%, 17 isolates). In cases of bacterial and fungal keratitis, filamentous fungus with Gram-positive bacterial infection (70.7%, 29/41) was the most common presentation. Visual improvement after treatment was common in the KOH-positive group (79.2%, 19/24), while visual deterioration after treatment was common in the culture-positive group (40.4%, 36/89). Previous ocular disease (odds ratio [OR]: 3.744, p = 0.010), hypopyon (OR: 2.941, p = 0.030), and surgical treatment (OR: 24.482, p < 0.001) were risk factors for a poor clinical outcome in the multivariate logistic regression model. Conclusions: Clinical prognosis was good in the KOH-positive only group, but poor in the culture-positive group. If fungal keratitis is suspected, diagnostic KOH staining and culture tests should be performed initially. Early intensive antifungal medical treatments are necessary for patients with risk factors for poor clinical outcomes.

반복각막진무름 환자의 임상양상 및 치료 효과

배경화(Kyoung Hwa Bae),안민(Min Ahn),조남천(Nam Chun Cho),유인천(In Cheon You) 대한안과학회 2016 대한안과학회지 Vol.57 No.4

목적: 반복각막진무름 환자들의 임상양상과 치료 효과를 알아보고자 한다. 대상과 방법: 2008년 1월부터 2015년 3월까지 본원 안과에서 반복각막진무름을 진단 받은 환자 48명 53안을 대상으로 의무기록을 후향적으로 분석하였다. 질환의 발생과 관련하여 환자들의 나이, 성별, 병변의 위치, 발생 원인을 분석하였다. 치료법에 따라 점안약치료만 시행한 A군, 점안약 치료에 치료용 콘택트렌즈 착용을 병행한 B군, 양막이식술을 시행 받은 C군, 기타 시술을 받은 D군으로 나누었으며, 치료 받은 인원이 적은 D군을 제외하고 A, B, C 각 군의 재발률을 확인하고 비교하였다. 결과: 환자들의 평균 나이는 45.6 ± 14.3세(19세-76세), 성별 및 좌우에 따른 발생률의 차이는 없었으며, 굴절수술을 받은 경우를 제외하고는 50대에서 호발하였다. 발생 위치는 하부(58.5%), 중심부(30.2%) 순이었으며, 발생 원인은 외상에 의한 경우, 원인을 알 수 없는 경우, 과거 굴절수술을 받은 경우, 기타 안질환과 관련된 경우 순으로 많았다. 전체 대상안 중 A군은 11안(20.8%), B군은 30안(56.6%), C군은 8안(15.1%) D군은 4안(7.3%)이었고 치료 방법에 따른 재발률은 A군 27.3%, B군 23.3%, C군 12.5%로 양막이식술을 시행한 군이 다른 군에 비해 의의 있는 차이를 보이지 않았으나 낮은 재발률을 보였다. 결론: 결론적으로 반복각막진무름은 굴절수술을 받은 경우를 제외하고 50대에서 호발하며, 가벼운 외상에 의해 각막하부에 잘 발생하고 점안약, 콘택트렌즈와 같은 치료에도 자주 재발하는 경우에는 양막이식술과 같은 수술적 치료가 도움이 될 것이다. Purpose: To investigate the clinical presentation and treatment outcomes of recurrent corneal erosion patients. Methods: Retrospective analysis was performed on the medical records of 48 patients (53 eyes) diagnosed with recurrent corneal erosion by our ophthalmology department between January 2008 and March 2015. Patient age, gender, lesion location, and cause of disease were analyzed against occurrence of disease. Patients were classified by treatment method into group A, which was treated with eye drops; group B, which was treated with therapeutic contact lenses and eye drops; group C, which was treated with amniotic membrane transplantation; and group D, which was treated with other procedures, and the recurrence rates were compared. Results: The mean age of patients was 45.6 ± 14.3 years (19-76 years), with no significant difference in recurrence rates dependent on gender or eye. Patients in their 50s were most affected, excluding refractive surgery patients. The most frequent lesion location was the inferior area of the cornea (58.5%), followed by the central area (30.2%), and the most common cause of disease was trauma, followed by unknown causes, past refractive surgery, and complications from other eye diseases. Group A had 11 eyes (20.8%), while groups B, C, and D had 30 eyes (56.6%), 8 eyes (15.1%) and 4 eyes (7.3%), respectively. The recurrence rates according to treatment method were 27.3% in group A, 23.3% in group B, and 12.5% in group C. The lower recurrence rate in the group treated with amniotic membrane transplantation was not significant compared to that of conservatively treated groups. Conclusions: Recurrent corneal erosion mostly affects patients in their 50s, excluding refractive surgery patients, and occurs frequently in the inferior area of the cornea due to mild trauma. Surgical treatment including amniotic membrane transplantation should be considered instead of conservative treatment in order to prevent reoccurrence.