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어병세균 Edwardsiella tarda에 대한 한약재 추출물의 항균활성
김아라 ( Ah Ra Kim ),김도균 ( Do Kyun Kim ),변태환 ( Tea Hwan Byun ),조은지 ( Eun Jee Jo ),이은우 ( Eun Woo Lee ),권현주 ( Hyun Ju Kwon ),김병우 ( Byung Woo Kim ),김태훈 ( Tae Hoon Kim ),이경본 ( Kyung Bon Lee ),김영만 ( Young Man 한국식품저장유통학회(구 한국농산물저장유통학회) 2011 한국식품저장유통학회지 Vol.18 No.1
The methanol extracts of 19 commercial herb medicines was analyzed to antibacterial activities against Edwardsiella tarda, causing several fish diseases. Rhus javanica showed most strong antibacterial activity against E. tarda and Escherichia coli. Methanol extract of R. javanica was further extracted using several organic solvents having different polarity. Extract from ethyl acetate fraction showed strong activity against E. tarda as well as E. coli. Minimal inhibitory concentration, MIC of R. javanica extract was measured and resulted showing 64 ㎍/㎖ for E. tarda and 256 ㎍/㎖ for E. coli. It is needed that, from these results, further purification and isolation of reposible compound of these activities and further study on the synergy effect using combination with antibiotics against pathogenic bacteria.