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Unsual Cytotoxic Phenethylamides form Xenerhabdus nemetophilus
백선국,박영환,서승일,김현수,이인선,박명광,이천수,박선호,Baek, Seon Guk,Park, Yeong Hwan,Seo, Seung Il,Kim, Hyeon Su,Lee, In Seon,Park, Myeong Gwang,Lee, Cheon Su,Park, Seon Ho Korean Chemical Society 2001 Bulletin of the Korean Chemical Society Vol.22 No.4
Three simple carboxamides incorporating the phenethylamine moiety have been isolated from strain XR-NC of a symbiotic bacterium Xenorhabdus nematophilus. Their structures were identified by spectroscopic data and synthesis. The compounds exhibited significant cytotoxicities against human cancer-cell line, viz. the gastric adenocarcinoma, colon adenocarcinoma and lung adenocarcinoma.