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저 전력 동작을 위한 뉴런 모방 회로의 파라미터 최적화
이정준(Jeong-Jun Lee),박정진(Jungjin Park),김형진(Hyungjin Kim),권민우(Min-Woo Kwon),백명현(Myung-Hyun Baek),황성민(Sungmin Hwang),박병국(Byung-Gook Park) 대한전자공학회 2016 대한전자공학회 학술대회 Vol.2016 No.6
This paper suggests proper parameters of MOSFETs in the basic model of neuron circuit which is previously proposed by our research group. With Floating-Body-Synaptic-Transistor, the neuron circuit constitutes neuromorphic system which can emulate the parallel operation of human brain. Through optimization of device parameters, the neuron circuit can operate with low power consumption and it can be efficiently integrated for high-density neuromorphic system.
全蝎 抽出物이 血栓症, 全腦虛血 및 腦細胞毒性에 미치는 影響
백명현,황영근,정지천,강정준,김성훈 동국대학교 한의학연구소 1999 東國韓醫學硏究所論文集 Vol.8 No.1
본 실험은 전갈 추출물이 어혈병태 모델과 KCN으로 유발된 전뇌허혈, 뇌세포독성 등에 미치는 영향을 관찰하였다. 전갈은 Dextran에 의해 유도된 혈전으로 감소된 혈소판수, fibrinogen량, hemocrit치를 유의성 있게 증가시키고. 증가된 prothrombin time을 유의성 있게 단축시켰다. 전갈은 thrombin과 ADP에 의해 유도된 혈소판 응집을 억제하였으나 collagen에 의해 유도된 혈소판 응집에는 저해효과를 나타내지 않았다. 또한 collagen과 epinephrine에 의해 유도된 pulmonary embolism에 대하여 보호 효과를 나타내었다. 전갈은 KCN에 의한 전뇌허혈 유발 실험에서 혼수시간을 유의성 있게 단축시켰고, Amyloid β protein(25-35)에 의해 유도된 PC12 세포의 독성에 대하여 보호효과를 나타내었다. This following is effect of Buthus martensi Karsch (BMK) extract on dextran-thrombus model, KCN-induced coma, cytotoxicity of brain etc. BMK extract significantly increased number of platelet and fibrogen and significantly shortened the prothrombin time as compared with control group treated with dextran. BMK extract didn't affect the changes of hematocrit as compared with control group treated with dextran. BMK extract induced a significant inhibition of human platelet aggregation induced by thrombin and ADP but did not affect human platelet aggregation induced by collagen. BMK extract showed a protective effect on pulmonary thrombosis induced by collagen and epinephrine. BMK extract prolonged the duration of KCN-induced coma and showed a protective effect on cytotoxicity of PC12 cells induced by amyloid β protein(25-35) in a dose dependent manner. These results suggested that BMK extract might be usefully applied for prevention and treatement of thrombosis and brain damage.