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        한국인 정상성인의 지질분포에 관한 연구

        정원태(Won Tae Chung),신영기(Yeong Kee Shin),배상균(Sang Kyun Bae),이민기(Min Ki Lee),이동일(Dong Il Lee),문창형(Chang Hyung Moon) 대한내과학회 1994 대한내과학회지 Vol.47 No.5

        N/A Objectives: The study was designed to establish normal serum lipid levels in the Korean adult population and to identify the effect of sex, age, blood pressure, body mass index (BMI), smoking, alcohol consumption, exercise, economic status, occupation and location on the serum lipid levels. Methods: The serum total cholesterol and triglyceride distribution in the normal Korean adult population were studied in 5,342 cases (males 2,834 and females 2,508) in the age groups of 3rd to 8th decades. Data were collected from 33 institutes and hospitals throughout the country during the period of June 1989 to December 1990. The serum lipid level were examined in the state of fasting of at least 12 hours and by the enzymatic method, Results: The mean level of serum total cholesterol was 183.6 mg/dl. Males had 181.9 mg/dl and females had 185.5 mg/dl without statistical significance between gender, but levels were significantly higher in the 4th decade in males and in the 6th, 7th and 8th decades in females. The mean level of serum triglyceride was 131.9 mg/dl. Males had 140.5 mg/dl and females had 122.2 mg/dl without statistical significance between gender, but levels were significantly higher in the 4th and 5th decades in males and in the 7th decade in females. The lipid levels rose gradually with the increase of age. The peak of serum total cholesterol and triglyceride level for the males was in the 6th decade and that for the females was in the 7th decade. The incidence of hypercholesterolemia with the standard of 240 mg/dl or more was 8.7% Males had 7.2% and females had 10.4% with the significantly higher incidence in females. The incidence of more than 220 mg/dl was 17.5% Males had 15.1% and females had 19.2% with higher incidence in females having statisticai significance. But there was no significant difference between big cities (cities controlled by central government) and smaller cities & towns in the incidence with either standard of levels. The incidence of hypertriglyceridemia of more than 200 mg/dl was 15%. Males had 18.0% and females had 11.5% with the significantly higher incidence in males. The incidence of more than 150 mg/dl was 29.1%. Males had 33.2% and females had 24.3% with higher incidence in males being significance. There was no significant difference between big cities and smaller cities & towns, The incidence of low serum total cholesterol less than 140 mg/dl was 12.4%, Males had 13.0%, and females had 11.7% without significant difference between gender. The incidence of less than 120 mg/dl was 3.7%. Males had 4.2% and females had 3.2%. It was significantly higher in males, and in the comparison between big cities and smaller cities & towns the incidence was significantly higher in smaller cities k towns compared with big cities in the standard of 140 mg/dl but not in the standard of 120 mg/dl. The significantly related factors for the serum total cholesterol level were age, sex, BMI, systolic blood pressure, occupation, location and family history. For the triglyceride level age, sex, BMI, diastolic blood pressure and smoking were the significantly related factors. Conclusion: The results of this research indicates that present lipid level profile in the adult Koreans is not a serious health situation. Additional research and on- going studies should be made to update this study. In addition an educational campaign to inform the medical profession and citizens of the danger of this health problem should be undertaken to avoid the health problems faced by other advanced countries.

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