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만성 염증성 장질환 환자에서 항호중구 세포질 항체의 의의
문윤재(Yoon Jae Moon),배희동(Hee Dong Bae),박효진(Hyo Jin Park),김원호(Won Ho Kim),정석훈(Suk Hoon Chung),김현숙(Hyun Sook Kim),전재윤(Chae Yoon Chon),박인서(In Suh Park) 대한내과학회 1997 대한내과학회지 Vol.52 No.5
N/A Objective: Anti-neutrophil cytoplasmic antibody (ANCA), known as a useful diagnostic marker in patients with ulcerative colitis (UC), are specific for granule proteins of granulocytes and monocytes and induce distinct fluorescence patterns. To evaluate the significance of ANCA in chronic inflammatory bowel disease (IHD), the presence of ANCA in chronic IBD was studied using indirect immunofluorescent test (IIF), Methods: Between March, 1994 and September 1995, 51 patients with chronic inflammatory bowel disease were subjected in this study. We had analysed the correlation between duration, disease activity, location by colonoscopy and radiologic examinations, steroid treatment. Results: 1) Among 34 patients with ulcerative colitis (UC), ANCA was demonstrated in 23 patients (67.6%). Among 19 patients with other chronic IBD (4 Crohn's disease, 6 Behcet's colitis, 7 intestinal tuberculosis and 2 radiation colitis) 2 patients (10.5%) had ANCA. The positivity of ANCA in patients with UC was significantly higher than in patients with other chronic IBD. 2) In patients with UC, c-ANCA was positive in 2 (5.9%) patients and p-ANCA was positive in 21 (61.8%) patients. In patients with other chronic IBD, ANCA was positive in one patient with Behcet's colitis or one patient with intestinal tuberculosis but negative in all patients with Crohn's disease or radiation colitis. 3) The mean duration of disease in ANCA positive patients was 42.4±39.4 months and the mean duration of disease in ANCA negative patients was 44.9±36.8 months, but there was no significant difference. 4) The number of patients in clinically mild, moderate and severe group were 23 (37.6%), 6 (83.2%) and 5 (14.7%) respectively. Among these groups the number of ANCA positive patients were 15 (65.2%), 5 (83.2%) and 3 (60%) respectively, but there was no significant difference. 5) The number of patients with proctitis, left side colitis and pancolitis were 9 (26.5%), 14 (41.2%) and 11 (32.4%) respectively, Among these groups the number of ANCA positive patients were 4 (44.4%), 10 (71.4%) and 9 (81.8%) respectively, but there was no significant difference. 6) Among 13 patients with steroid treatment 9 patients (69.2%) were ANCA positive. Among 21 patients without steroid treatment 16 patients (76.2%) were ANCA positive, but there was no significant difference. Conclusion: Although there was no correlation between ANCA and duration, disease activity, location or steroid treatment in UC patients, ANCA could be a diagnostic marker of UC in chronic IBD patients.
문윤재(Yoon Jae Moon),황준영(Jun Young Hwang),강희석(Heuiseok Kang),강경태(Kyungtae Kang),문승재(Seung-Jae Moon) 대한기계학회 2010 대한기계학회 춘추학술대회 Vol.2010 No.11
Electrical sintering of silver nanoparticles was performed using operational amplifier (OP amp) to apply a constant DC current. Conducting lines were printed on glass substrate by a drop-on-demand (DOD) inkjet printer and silver nanoparticle ink. Specific resistance and microstructure of sintered silver lines and were measured with varying DC current. Sintering process finished within a few milliseconds. Increasing applied DC current, specific resistance decreased and gain size increased. Achievable minimum specific resistance is approximately two times higher than specific resistance of bulk silver.
윤재문(Youn Jae Moon) 한국정치정보학회 2004 정치정보연구 Vol.7 No.1
본 논문은 김정일 체제하의 북한 외교정책의 환경 변화요인과 그 대응전략을 분석하였다. 우선 북한의 외교정책 목표가 탈냉전기의 새로운 환경에 맞게 재조정된 것은 무엇보다도 기존에 우호적인 관계를 맺고 있던 중국과 러시아의 대북한 관계변질, 가중되는 경제난에 따른 체제불안, 자력갱생이 불가능환 상황에서 남한을 비롯한 미국 등 외부의 경제협력 및 지원의 필요성 인식 등이 그 바탕이 되고 있었다. 김정일 사대 북한외교정책은 과거와는 달리 모든 나라들과 정치 군사적 유대협조보다 경제적 실리를 챙기고 경제교류협력을 활성화하는 데 초점을 맞추는 이른바 ‘실리외교’의 모습을 보이고 있다. 향후 북한 외교정책의 양상은 현재와 같이 보다 적극적이고 공세적 자세를 취할 것이다. 또한 실리외교를 축으로 하되 최대한 명분도 확보하는 전략을 취할 가능성이 높다. 특히 명분 확보와 관련해서 보면, 북한은 현재 탈냉전 초기와는 달리 어느 정도 경제회복의 기미를 보이고 있는 것이 사실이고, 미국을 비롯한 적대국들의 대북 정책 역시도 북한의 체제붕괴 보다는 연착륙을 지향하고 있다는 점 등에서 북한은 다소나마 대외정책에서 여유를 가질 수도 있는 상황으로 전환되고 있기 때문이다. This treatise was analyzed factors of change of diplomatic surroundings below Kim Jungil's System in North-Korea and confrontation strategy. First of all, readjusting a goal of a diplomatic policy, toward new situation in The Post-cold War, was based on recognitions of economic cooperations and supports, South-Korea. United states and so on, because North-Korea was these situations: China and Russia's changes which were on friendly relations. a system insecurity as heavy financial difficulties, impossible self-rehabilitation. North-Korea diplomatic policy in Kim Jung-il's system is utility diplomacy, which gets economic utility more than politic and military relation cooperation with other countries, unlike a past, and brings focus into activating an economic interchange cooperation. From now on, an aspect of North-Korea diplomatic policy takes the posture active and scrappy like the present. Also, it is possible that they take a strategy to secure the most their moral duties in utilitarian policy. Especially, in the meaning of a justice security, it is true that North-Korea seems signs of recovery of economy, unlike the early of Post-cold war. and a policy toward North-Korea of hostile countries including United States also intends to a soft landing more than a structure collapse of North-Korea. In these reasons, North-Korea more or less is changed to have an afford in a foreign policy.