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- 저자 : 동형근(HJ Dong) (검색결과 4 건)
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이식암종물 세포하분획별 RNA에 있어서의 방사능전구물질의 결합률에 관한 실험적연구
동형근(HJ Dong) 대한산부인과학회 1968 Obstetrics & Gynecology Science Vol.11 No.4
The present studies were designed to determine the incorporation of radioactive precursor into tumor and hepatic RNA in solid tumor of rats. The animal used in these experiments were female rats, weighing 100-120 gm. The Walker 256 crcinosarcoma was transplanted 12 days prior to the experiment. The orotic acid _6_C14 was injected intravenously in a dose of 3.3?c/200gm. of body weight. At 15min. and 60min. after the injection of radioactive orotic acid the rate were sacrificed and the liver and tumor tissues were excised. By the differential centrifugation, the nuclear, mitochondrial, microsomal and supernatant fractions were fractionated. The RNA of the various cellular componenets were fractionated with phenol and buffer to give phenol extractable RNA(p-RNA) and a residual RNA(r-RNA) which remained in the Phenol phase. The radioactivity of p-RNA and r-RNA of each cellular fractions were determined in windowless gas flow counter. The RNA was assayed by ordinal method and the specific activity were calculated. The results obtained were as follows: 1. The specific activity of r-RNA in all cellular fractions of the liver were markedly high compared to p-RNA. The maximum incorportion was found at 30min. after the injection of radioactive orotic acid in both nuclear p-RNA and r-RNA and at 60min. in all cellular fraction except nuclear. 2. Although the incorporation rate of radioactive orotic acid into the nuclear and mitochodrial p-RNA of Walker tumor was unchanged compared to liver, microsomal incorporation rate was increased 1.7 times at 15min., 2.3 times at 30min., 1.3 times at 60min. and supernatant fraction was incrased 2.2 times at 15min., 1.7 times at 60min. after the injection of orotic acid. 3. The incorpioration of radioactive orotic acid into the nuclear r-RNA of Walker tumor was increased 2.6 times at 15min., 2.1 times at 30min. and 2.6 times at 60min., and the mitochondrial incorporation rate was increased 1.5 times at 15min., 1.8 tiems at 30min., 1.6 times at 60min. compared with hepatic r-RNA. The incorporation rate of radioactive orotic acid into the microsomal and supernatant r-RNA were not changed. 4. It was shown that increased incorporation of labeled orotic acid into p-RNA of microsomal and supernatant and into the r-RNA of nuclear and mitochondrial fractions were caused by essential and excessive biosynthesis of protein in rapid growing neoplastic tissues.
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정규석(KS Chung),동형근(HJ Dong),송석규(SK Song),노희중(HJ No) 대한산부인과학회 1966 Obstetrics & Gynecology Science Vol.9 No.7
One case of anencephalus with hydramnios at the 28 weeks of pregnancy of 32 year`s old is presented and another case of anencephalus is presented with hydramnios and equinovarus at the 36 weeks of pregnancy of 27 year`s old. And a brief review on anencephalus is presented.
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박희설(HS Park),동형근(HJ Dong),채유병(YB Chae) 대한산부인과학회 1966 Obstetrics & Gynecology Science Vol.9 No.3
Lippe`s loop is a kind of intrauterine contraceptive devices which is good for it`s easy insertion, removal, effectiveness, and rather rare complication. Auther represent a case of intraabdominsl loop which was developed possible due to uterine perforation on insertion of the loop.
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채유병(YB Chae),박희설(HS Park),동형근(HJ Dong),이헌영(HY Lee) 대한산부인과학회 1966 Obstetrics & Gynecology Science Vol.9 No.4
Abdominal or ovarian pregnancy has been regarded as a rare condition that freequently imposes diagnostic problem. The present communication is concerned with the experience with two cases of abdominal pregnacy as diagnosed and treated at the Department of Obsterics and Gynecology, st. Mary`s Hospital, Catholic Medical College in the month of May 1965. A review of pertinent literature is included as well. Case Ⅰwas 7th month of gestation and contained a dead male fetus in breech presentation. The fetus measured 37.5㎝ in height, and 1,250 gram in weight. No abnormality or deformity could be seen. Case Ⅱ was 4th month of gestation and contained a dead male fetus which measured 11.6 ㎝ in height and 108 gram in weight without demonstrable deformity. In each case, the fetus was removod with placenta and exstirpation of the uterus followed. Both cases were considered to be secondary to ruptured early tubal pregnancy.
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