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- 저자 : 노재숙(Jae Sook Rho) (검색결과 4 건)
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한국인 중증 전자간증 산모에서 Thermolabile Methylenetetrahydrofolate Reductase 유전자의 다양성에 관한 연구
홍승화(Seung Hwa Hong),김용범(Yong Beom Kim),지일운(Ill Woon Ji),정은환(Eun Hwan Jeong),김학순(Hak Soon Kim),노재숙(Jae Sook Rho),김정규(Jeong Kyu Kim),조명찬(Myeong Chan Cho) 대한산부인과학회 2001 Obstetrics & Gynecology Science Vol.44 No.11
N/A Objective : This study was performed to evaluate C to T substitution at nucleotide 677 of meth- ylenetetrahydrofolate reductase gene in Korean women, which is genetically homogeneous, with preeclamptic or normotensive pregnancies. Methods : Methylenetetrahydrofolate reductase genotypes were determined in 63 Korean women with severe preeclamptic pregnancies and 60 controls with normotensive pregnancies, using polymerase chain reaction and restriction enzyme analysis. Results : The methylentetrahydrofolate reductase genotype and allele frequencies in preeclamptic and control women did not differ significantly. The frequency of the T677 allele was 38.1% in the preeclamptic group and 41.7% in the control group, and TT homozygosity was found in 12 preeclamptic women (19.0%) and 10 controls (16.7%). Conclusion : It seems like that there is no evidence of association of preeclampsia with methylenetetrahydrofolate reductase gene polymorphism, at least in the Korean population.
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내시경수술용 자동봉합장치를 이용한 경질적 천극인대고정술 1례
지일운,정은환,김학순,노재숙 충북대학교 의과대학 충북대학교 의학연구소 1998 忠北醫大學術誌 Vol.8 No.2
산부인과 의사는 질탈출증을 교정하기 위한 수술 술기를 한 두 가지는 숙지하고 있어야 한다. 특히 질식 수술 법은 복식 수술 법보다 간단하기 때문에 입원기간이 짧고 여러 가지 장점이 많다. 질식 수술에는 고전적으로 needle holder, Deschamps ligature carrier, Miya hook, Shutt needle punch등이 사용되어 왔으나 최근에는 내시경수술용 자동봉합장치를 이용하여 보다 손쉽게 수술할 수 있는 방법이 제시되었다. 저자들도 이 방법으로 질탈출증 환자를 성공적으로 치료하였기에 문헌고찰과 함께 보고하는 바이다. Gynecologic surgeons should familiarize themselves with one or two well-accepted techniques performed via either the vaginal or the abdominal route so that the procedure that best fit the patients' needs can be performed in vaginal vault prolapse. The vaginal approach to the treatment of eversion of the vagina has many advantages over the transabdominal anterior fixation or posterior sacropexy. The procedure requires a shorter hospital stay and lesser amount of operation. The procedure has been described using a straight or curved needle holder, a Deschamps ligature carrier, a Miya hook, and a Shutt needle punch. The technique of sacrospinous ligament fixation with the Autosuture Endostitch device was described by Papasakelariou and Baker in 1996. We also performed the transvaginal sacrospinous ligament fixation with the Autosuture Endostitch device, and present the case with brief review.
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자궁경부암 환자에서 합병된 자궁내막증의 요관침범에 의한 경증의 수신증
김학순,정은환,노재숙,지일운 대한산부인과학회 2000 Obstetrics & Gynecology Science Vol.43 No.8
The diagnosis of ureteral stricture caused by endometriosis can be difficult. Especially does in the case combined with other gynecological malignancies such as cervical cancer. We present a 50-year-old perimenopausal woman who had undergone radical hysterectomy, bilateral salpingo-oophorectomy, pelvic lymphadenectomy, and incidental appendectomy under the diagnosis of cervical cancer stage Ib1, who also had right ureteral endometriosis which was incidently found during operation and was treated with segmental resection and reanastomosis of the right ureter. Microscopic examination of the ureter and surrounding resected tissue confirmed the lesion to be typical endometriotic origin. Mild hydronephrosis on CT scan prior to operation made us to be confused with ureteral involvement by cervical cancer. However, when mild hydronephrosis or ureteral stricture exists in the case of an earlier stage of cervical cancer, physicians should consider a possibility of ureteral involvement rather by other causes like endometriosis than cancer invasion.
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자궁내막증 환자와 정상 여성 간에 배란 전 난포액 및 복강액 내 PGF2α의 농도비교
윤태진,김용범,김학순,정은환,노재숙,지일운,민경준,신서규 대한산부인과학회 2000 Obstetrics & Gynecology Science Vol.43 No.11
Objective : The aim was to evaluate whether the differences of PG concentration in follicular and peritoneal fluid during preovulatory phase exist between the women with and without endometriosis. Material and Methods : Twenty-three patients with endometriosis, 8 were stage I-II and 15 were stage III-IV, and another 23 patients without endometriosis were undergone laparotomy during late follicular phase. Peritoneal fluid from 46 patients and follicular fluid from 42 patients were obtained, and these samples were analyzed double times for PGF2α, PGE2 and estradiol. Results : The mean level of PGF2α in the peritoneal fluid was significantly higher in the group with endometriosis than in the control(P=0.0293), especially more significant in stage I-II endometriosis. Although there was no significant difference of PGF2α concentration in the follicular fluid between the groups, the stage III-IV endometriosis group showed slightly higher PGF2α level than both the stage I-II group and the control(P=0.0604). And also, there was significant positive correlation with the level of PGF2α and estradiol in the follicular fluid only in the endometriosis group(r=0.4988, P=0.0154), not in the control. However, there was no difference in the level of PGE2 and estradiol in the peritoneal or follicular fluid between the groups. Conclusion : Some alterations of PGF2α level exist in the women with endometriosis. These are significantly higher PGF2α level in peritoneal fluid with mild endometriosis and slightly higher PGF2α levels in follicular fluid with extensive endometriosis during preovulatory phase, which suggest that PGF2α may play some roles in subfertility associated with endometriosis.
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