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金禮會 公州大學校 資源科學硏究所 1993 資源科學硏究論文集 Vol.1 No.-
This study was conducted to develop the vegetative propagation techniques of mature Tilia mandshurica by cutting. Cuttings were taken from normal branches or sprouts of 25-years-old trees. Fine sand and artificial soil mixture(a 1:1 volume of peatmoss and vermiculite)were used as rooting media, and 300ppm IBA treated for rooting. The following results were obtained: 1. The rooting was better on artificial soil mixture than on fine sand. 2. Normal branches did not rooted at all, but the sprouts showed rooting rate up to 38.0%. 3. IBA treatment promoted the adventitious root formation, though had no effect on root elongation.
胃癌에서 Nitrosoureas와 Pyrimidine Analogs의 效果
김예회,김관엽,이혁상,백인욱,백낙환 인제대학교 1980 仁濟醫學 Vol.1 No.1
50명의 진행된 위암환자를 대상으로 nitrosourea계의 항암제인 CCUN 및 pyrimidine analog인 5-FU 또는 ftorafur를 병용하여 23명의 환자(46%)에서 뚜렷한 항암효과를 얻었다. CCNU 및 5-FU 병용요법을 근처적 위절제술이 가능한 환자에서 수술후 보조적 항암요법제로 사용하여 본 결자 재발의 지연내지는 예방하는데 고무적이며 이에 대하여는 보다 많은 환자를 대상으로 장기적인 추적조사가 필요하다고 생각된다. Fifty patients with advanced gastric cancer who were not previously treated with cytotoxic drugs were treaded with CCNU and pyrimidine analogs(fluorouracil or ftorafur). The first group of 38 patients were given CCNU and 5-fluorouracil in combination. The following dose schedule was used: CCNU, 150mg was given by mouth on day 1: 5-FU, 500mg was given intravenously as bolus on days 1 to 4. Each course was repeated at 6 weeks interval. There were18 responders(47%). The median duration of response was 5 months. The second group of 12 patients were treated with CCNU and ftorafur in combination. The dose schedule was as follows: CCNU, 150mg was given on day 1 and retreated at 6 weeks interval. Ftorafur was given by mouth 200mg tid daily until leukocyte count falls below 2,000. There were 5 responders (42%). The duration of reponse ranges from 2 months to 6+mosnths. The combination regimen with CCNU and fluorouracil or its derivative (ftorafur) appears to be very effective for advanced gastric cancer. The result of a preliminary study obtained from trial of the above chemotherapy regimen for patients with stomach cancer as a adjuvant setting is encouraging.
金禮會 인제대학교 1981 仁濟醫學 Vol.2 No.4
During the past decade gastric cancer has emerged as the most responsive tumor to chemotherapy among gastrointestinal adenocarcinoma. With best polychemotherapy regimen 50% response rate could be achievable. The regimens reported to be effective contain nitrosoureas(BCNU, CCNU, methyl-CCNU), 5-FU, mitomycin-C, and doxorubicin in various forms of combination. The efficacy of these regimens as post-surgical adjuvants are being tested to improve surgical cure rate.
進行된 胃癌에서 CCNU, Adriamycin, 5-Fluorouracil 三劑倂用治療의 效果
金禮會,李健周,金喆守,金官曄 인제대학교 1982 仁濟醫學 Vol.3 No.1
Twentry-five patients with advanced metastatic or unresectable adenocarcinoma of stomach were given combination chemotherapy consisting of CCNU, adriamycin, and 5-fluorouracil. One patient achieved complete remission and seven partial remission to give an overall response rate of 32%. The duration of remission ranged from two months to 14 months and the median duration of remission was 5 months. The combination regimen was well tolerated, and produced moderate bone marrow toxicity.