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김수찬 ( Kim Su Chan ),안규중 ( An Gyu Jung ),한승경 ( Han Seung Gyeong ),김진우 ( Kim Jin U ),성경제 ( Seong Gyeong Je ),계영철 ( Gye Yeong Cheol ),김낙인 ( Kim Nag In ),조광현 ( Jo Gwang Hyeon ),김광중 ( Kim Gwang Jung ),윤재일 대한피부과학회 2003 대한피부과학회지 Vol.41 No.9
전국의 31개 병의원에서 10개월간 피부과 내원환자 중 피부외용제에 의한 부작용을 나타낸 1257예의 사례를 수집하여 분석하였으며 다음과 같은 결과를 얻었다. 1) 외용제에 의한 부작용은 오용 및 치료지연(40%), 진균감영(29%), 세균감영(14%), 접촉피부염(9%), 여드름, 피부위축, 혈관확장 등의 순으로 그 빈도가 높았으며 스테로이드 도포에 의한 부작용은 모두 620건(49%)에 달하였다. 2) 오용의 경우 백선증을 습진으로 오진한 경우가 7 Background : The abuse, misuse, and adverse effects to topical drugs have been widespread in Korea due to lack of awareness of seriousness of drug abuse and misuse, and improper designation of prescription and non-prescription drugs. Objective : This stud
운동방정식을 기저로 한 스튜워트 플랫폼 운동장치의 제어시스템 설계 및 슬라이딩 모드제어
이종원,김낙인,Lee, Chong-Won,Kim, Nag-In 대한기계학회 1999 大韓機械學會論文集A Vol.23 No.6
A high speed tracking control system for 6-6 Stewart platform manipulator is designed for performing the model based joint-axis sliding mode control. Because of the complex dynamics and kinematics of the Stewart platform manipulator, two computer systems, consisting of a PC and a DSP, are adopted, so that real time tasks are run in synchronous and asynchronous modes. It is experimentally proven that the proposed control system makes the convenience in implementation of model based tracking control, so that it can achieve effective tracking control under relatively high speed and additional payload conditions.
건선의 중증도와 혈청 soluble E-selectin, MCP-1 및 RANTES에 관한 연구
박정훈 ( Park Jeong Hun ),김낙인 ( Kim Nag In ) 대한피부과학회 2004 대한피부과학회지 Vol.42 No.2
N/A Background: Psoriasis is a chronic skin disease characterized histologically by prominent keratinocyte hyperplasia and an early inflammatory cell infiltrate. However the pathogenesis is not fully understood yet. Recently, the evidence that T lymphocytes play a key tole in the pathogenesis of psoriasis is compelling. Objective: The purpose of this study is to cvaluate serum soluble E-selectin, MCP-1 and RANTES as severity indices of disease marker. In this study, we investigated a possible correlation between disease activity in psoriasis and serum soluble E-selectim, MCP-1 and RANTES, respectively. Methods: Fifteen patients with psoriasis and fifteen normal controls were included in this study. The patients were evaluated for the symptoms and signs accotding to PASI score. We measured soluble E-selectin, MCP-1 and RANTES levels with blood samples drawn from patients and normal controls. Results: 1. Soluble E-selectin serum levels were significantly increased in psoriatic patients compared with normal controls (p<0.05). Moreover, a significant correlation was demonstrated between serum soluble E-selectin values and PASI scores (r=0.54, p<0.05). 2. Serum MCP-1 levels were significantly increased in psoriatic patients compared with normal conrlos (p<0.05). However, no significant correlation was observed between MCP-1 values and PASI scores (r=0.12). 3. Serum RANTES levels were significantly increased in psoriatic patients compared with normal controls (p<0.05). Moreover, a positive correlation was observed between serum RANTES levels and PASI scores (r=0.63, p<0.05). Conclusion: These results suggest that serum levels of soluble E-selectin and RANTES could be used as marker of the disease activity in psoriatic patients. (Korean J Dermatol 2004:42(2):138~144)