ACCase 및 ALS 저해 제초제들에 대한 저항성 강피의 반응과 대체약제들의 효과

박태선(Tae-Seon Park),구본일(Bon-Il Ku),강신구(Sin-Koo Kang),최민규(Min-Kyu Choi),박홍규(Hong-Kyu Park),이경보(Kyong-Bo Lee),고재권(Jae-Kwon Ko) 韓國雜草學會 2010 Weed&Turfgrass Science Vol.30 No.3

ACCase 저해해제인 cyhalofop-butyl과 ALS 저해제인 penoxsulam은 한국의 직파재배 논에서 수년 동안 경엽 처리용으로 사용되어지고 있다. 그러나 2009년 이후 익산, 김제, 부안에서 이들 제초제를 사용한 벼 직파재배 논에서 강피 약효에 대한 민원이 증가하고 있다. ACCase 및 ALS 저해제 저항성으로 추정되는 강피를 3개 지역에서 수집하여 온실조건에서 cyhalofop-butyl과 penoxsulam에 대한 저항성 정도를 검증하였다. 익산과 김제의 수집종은 cyhalofop-butyl과 penoxsulam의 추천량에서 완전 생존하였으며, 부안 수집종은 약 60% 생존하였다. 온실조건에서 화본과 잡초인 피를 방제를 위한 ACCase 및 ALS 저해제들 이 혼합된 제초제들을 강피 3.5엽기에 처리한 결과 무처리 대비 생존율은 80% 이상으로 나타났다. 파종 및 이앙전 처리제들인 oxadiazon EC, pyrazolate SC, pretilachlor EC, benzobicyclon+thiobencarb SE들은 강피 0.5엽기에서 효과적이었으며, benzobicyclon+fentrazamide+bensulfuron SC, benzobicyclon+mefenacet+bensulfuron SC 그리고 benzobicyclone+cafenstrole+pyrazosulfuron-ethyl GR은 강피 2엽기까지 효과적으로 방제하였다. 포장실험에서 benzobicyclon+fentrazamide+bensulfuron SC과 benzobicyclon+mefenacet+bensulfuron SC의 단일처리에서는 저항성 강피의 방제에 실패하였으나, benzobicyclon+thiobencarb SE와 benzobicyclon+mefenacet+bensulfuron SC의 체계처리는 강피를 효과적으로 방제하였다. 따라서 강피의 익산, 김제 수집종은 cyhalofop-butyl과 penoxsulam에 대하여 강한 저항성을 보였으나, 작용기작이 다른 cafenstrole, fentrazamibe, mefenacet에 의해 2엽기 이내에는 효과적으로 방제되었다. Cybalofop-butyl and penoxsulam, known for respective acetyl CoA carboxylase (ACCase) and acetolactate synthase (ALS) inhibitor, have been widely using as a post-emergence foliar application for many years in wet-seeded rice field in Korea. Since 2009, control of Echinochloa oryzoides with cyhalofop-butyl and penoxsulam was no longer satisfactory. Greenhouse and experiment in rice field were conducted to confirm E. oryzoides resistance to ACCase and ALS inhibitors and to compare herbicide treatments for control of the resistant E. oryzoides to ACCase and ALS inhibitors. Three resistant E. oryzoides to ACCase and ALS inhibitors accessions were tested for levels of resistance to cyhalofop-butyl and penoxsulam, base on survival rate. Iksan and Kimje accessions were not any affected to the survival by treatment with recommended doses of two herbicides tested. Buan accession displayed an intermediate response of 62 and 72% survival at recommended doses of cyhalofop-butyl and penoxsulam, respectively. Survival rates to herbicides mixed with ACCase and ALS inhibitors at 3.5 leaf stage of E. oryzoides was over 80%. Benzobicyclon+fentrazamide+bensulfuron SC, benzobicyclon+mefenacet+bensulfuron SC, benzobicyclone-cafenstrole+pyrazosulfuron-ethyl GR controlled effectively by 2 leaf stage of resistant E. oryzoides to ACCase and ALS inhibitors. In the field experiment, single treatment of benzobicyclon+ fentrazamide+bensulfuron SC and benzobicyclon+mefenacet+bensulfuron SC failed to control E. oryzoides, but squential treatment of benzobicyclon+thiobencarb SE and benzobicyclon+ mefenacet+bensulfuron SC controlled effectively it in rice infant seedling culture with machine. Our results suggest that resistant E. oryzoides to ACCase and ALS inhibitors had not developed multiple resistance to herbicides with different modes of action. In particular, cafenstrole, fentrazamide, mefenacet were effective control measures.

남부지역 무논직파 재배 논에서 잡초 방제

박태선,박홍규,강신구,구본일,최민규,이경보,고재권,Park, Tae-Seon,Park, Hong-Kyu,Kang, Sin-Koo,Ku, Bon-Il,Choi, Min-Kyu,Lee, Keong-Bo,Ko, Jae-Kwon 한국잡초학회한국잔디학회 2012 Weed&Turfgrass Science Vol.32 No.1

This study was conducted to find the effective management of main weeds including herbicide-resistant Echinochloa oryzicola, Scirpus juncoides and Monochoria vaginalis in direct seeded rice on puddled paddy surface. The dominant dominances in direct seeded rice on puddled paddy surface were increased for three years between 2009-2011. In weed distribution in 2011, the occurrence density of S. juncoides decreased greatly, but it of E. oryzicola increased especially as compared with it of 2009. Benzobicyclon, mesotrione and pyrimisulfan were effective to sulfonylurea(SU)-resistant S. juncoides and M. vaginalis at 5 and 12 days after seeding, however, the efficacy of bromobutide to sulfonylurea-resistant M. vaginalis was decreased slightly at 12 days after seeding. And carfentrazon and pyrazolate were ineffective to S. juncoides. In direct seeded rice on puddled paddy surface which ACCase and ALS inhibitor-resistant E. oryzicola was not occurred, benzobicyclon+penoxsulam+pyrazosulfuron-ethyl ET, bromobutide+imazosulfuron+metamifop GR, and flucetosulfuron+mesotrione+pretilachlor GR showed the control effect over 94% to main weeds included sulfonylurea-resistant S. juncoides and M. vaginalis. The E. oryzicola dominating in direct seeded rice on puddled paddy surface were not any affected to the survival by treatment with recommended doses of cyhalofop-butyl and penoxsulam tested. The ACCase and ALS inhibitor-resistant E. oryzicola was effectively controlled by mefenacet and fentrazamide up to the 2nd leaf stage. In direct seeded rice on puddled paddy surface domiating coincidentally by herbicide-resistant E. oryzicola, S. juncoides and M. vaginalis, "one-shot herbicide" included with mefenacet, fentrazamide, penoxsulam and metamifop could't be used because of low control effect or rice injury. The sequential treatment of benzobicyclon+thiobencarb SE and bensulfuron+mefenacet+thiobencarb GR controlled effectively the herbicide-resistant E. oryzicola, S. juncoides and M. vaginalis in direct seeded rice on puddled paddy surface. The days required by the 3rd leaf stage of herbicide-resistant E. oryzicola, S. juncoides and M. vaginalis in direct seeded rice on puddled paddy surface seeded in May 20 shortened by 4 days as compared with it of June 10.

회전근개 손상의 특징에 따른 유착성 관절낭염 이환 시기와의 상관관계

허광호 ( Kwang Ho Heo ),이창형 ( Chang Hyung Lee ),민지홍 ( Ji Hong Min ),김수연 ( Soo Yeon Kim ),박예진 ( Yeo Jin Park ),구본일 ( Bon Il Koo ),김상훈 ( Sang Hoon Kim ),신용일 ( Yong Il Shin ),황의형 ( Eui Hyoung Hwang ) 한방재활의학과학회 2014 한방재활의학과학회지 Vol.24 No.1

ObjectivesAdhesive capsulitis (AC) is a restricted shoulder range of motion. Rotator cuff disease (RCD) has been believed to be a major etiologic factor of AC, however, how soon is the development time from RCD to AC (DTRA) has not been elucidated. The purpose of our study was to evaluate the correlation between the ultrasonographic characteristics of RCD and the DTRA. MethodsTotal 40 patients who were diagnosed as AC were recruited. The clinical char-acteristics of RCD were diagnosed by ultrasonography and classified with the Southern California Orthopedic Institute for Rotator Cuff Classification. The correlation was analyzed with Mann-Whitney U test and one-way analysis of variance.Results60% of full thickness tear and 40% of partial thickness tear patients (10 male and 30 female, mean age of 54.0±8.4 years) and 38% of bursitis and 21% of neo-vascularization were observed. The mean value of DTRA was 74.8±131.3 days. There were no correlation between DTRA and gender (p=0.63), location of the partial tear (p=0.63), the severity of the partial thickness tear (p=0.63), full thickness tear (p=0.66) and completeness of the tear (p=0.16). The presence of bursitis or neovascularization was not associated with DTRA (p=0.60, p=0.61).ConclusionsAlthough RCD is a major etiologic factor of AC, the severity, the type of RCD and the presence of bursitis and neovascularization were not statistically correlated with the DTRA in our study. Comprehensive consideration about etiologic factor analysis of AC will be needed with prospective study design for future study. (J Korean Med Rehab 2014;24(1):77-82)

40세 이상 환자에서 심방중격결손의 치료

최웅규,박용원,구본일,오상준,이홍섭,최석구,김상우 인제대학교 1998 仁濟醫學 Vol.19 No.2

심방중격결손증은 성인 연령층에서 발견되는 가장 흔한 선천성 심질환으로, 외과적 교정을 받지 않은 중년의 환자에서는 점차 폐고혈압, 심방부정맥, 울혈성 심부전, 심방세동, 색전증 등의 빈도가 점차 증가한다. 인제대학교 서울백병원에서 1988년 5월부터 1997년 5월까지 지난 10년간 40세 이상 중년에 이차공성 심방중격결손증을 가진 20명의 환자에 대하여 직접 봉합술을 실시하였다 수술의 결과는 좋았고 수술 후 사망은 없었으며, 고연령을 포함한 모든 환자들은 수술 후 적어도 NYHA(New York Heart Association) functional class I 이상의 개선이 있었다. 그러므로 성인의 심방중격결손의 치료에 있어서 고령이거나, 어느 정도의 폐동맥 고혈압이 동반되더라도 수술을 시도하는 것이 최선의 치료가 될 것으로 생각되는 바이다. This study showed clinical results of 20 patients aged 40 years or older undergoing surgical repair of isolated secundum atrial septal defect at Inje university, Paik hospital during the period from May 1988 to May 1997. ASD was closed with direct suture in all patients. Responses to surgery were excellent. We had no operative mortalities, and good clinical improvements of more than one class according to New York Heart Association functional classification. An old age was not a contraindication to surgery.

좌심방 점액종 치험 1례보고

이윤우,박영우,최석구,유원상,구본일,박국양,이홍섭,김창호,윤귀옥,고일향 인제대학교 1987 仁濟醫學 Vol.8 No.3

A 56 year-old woman admitted to our hospital because of progressive exertional dyspnea for 2 months. Preoperative clinical diagnosis of left atrial myxoma was made from M-mode and 2-dimensional echocardiography, and the tumor was removed successfully with the aid of extracorporeal circulation on October 23,1986, which was the first open heart surgery in Paik Hospital, Seoul. We report a case of left atrial myxoma with a review of literatue.