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고창용(C. Y. Ko),우대곤(D. G. Woo),이태우(T. W. Lee),김한성(H. S. Kim),이법이(B. Y. Lee),탁계래(G. R. Tack) 한국정밀공학회 2005 한국정밀공학회 학술발표대회 논문집 Vol.2005 No.10월
This study investigated the effect of ovariectomy (OVX) on the rat bone for long term (22 weeks). In previous researches, there were many studies for morphology of OVX-induced osteoporotic bones based on micro-Computed Tomography (micro-CT). However, there were few studies for detecting and tracking changes of mechanical characteristics in the lumbar vertebrae of OVX rat for long-term. For this study, one female Sprague-Dawley rat was used: an OVX rat. The 4th lumbar of the OVX rat was utilized as a specimen. Morphological characteristics could be investigated for the lumbar vertebrae in an OVX rat by using in-vivo Micro-CT. An OVX rat was scanned at week 0 (just before surgery), at week 4, at week 8, at week 16 and at week 22 after surgery. Micro finite element (μFE) analysis was used to investigate mechanical characteristics in the lumbar vertebrae for an OVX rat.