알콜유도 지질과산화에 미치는 어성초 영향

강탁림,Kang Tak-Lim 대한예방한의학회 1998 대한예방한의학회지 Vol.2 No.1

The antilipidperoxidative and hepatopreventive effects of Houttuynia cordata extract(HCE) were investigated at the level of liver homogenates and serum of SD rats intoxicated EtOH(3g/kg for 3days). We measured MDA(malondialdehyde) in the live. homogenate, AST(1-aspartate-2-oxoglutarate aminotransferase) and ALT( 1-alanine-2-oxoglutarate aminotransferse) in the serum. The analysis of the measurement indicated that HCE reduced MDA, ALT and AST significantly and their reduction was in relation to dose dependence. In rat liver homogenate intoxicated with EtOH, HCE treatment group inhibited lipidperoxidation by 50-75%. In rat serum intoxicated EtOH, HCE inhibited AST and ALT by 40-70%.

어머니會가 이웃 사이의 家族計劃 코뮤니케이숀 樣相에 미친 影響에 對한 事例硏究

康坼林 서울大學校 保建大學院 1976 公衆保健雜誌 Vol.13 No.1

Mothers' clubs are local groups of women organized as a means of promoting the diffusion of family planning. One of the basic assumptions underlying the family planning program through mothers' clubs is that they favorably affect the pattern of communication on family planning among village women so as to improve the program performance. This study is an attempt to examine the validity of the assumption. Thus two hypotheses were proposed for this study: 1. There would be differences in the pattern of family planning communication between the villae with mothers' club and the village without mothers' club. 2. The impact of mothers' club on family planning communication would result in the higher level of family planning knowledge, favorable attitude, and practice in the village with mothers' club than in the village without mothers' club. In order to test these hypotheses, this study has made comparative anylyses of general characteristics, family planning status, and family planning communication network of the women in two villages, one with mothers' club and the other without mothers' club. This study used part of the data collected for the study of family planning IEC activites by the School of Public Health, Seoul National University in November 1974. In the communication network analysis, the method proposed by William Richards, Jr. was used. The findings confirmed the hypotheses as generally valid. The village with mothers' club showed the communication network which had only three isolates and three distinguishable cliques with six bridge agents. On the other hand, the village without mothers' club had no distinguishable clique and seven isolates. In the light of the tabooness of family planning topics in communication, the communication structure with divided small cliques, supposedly composed of more intimate group members, would be adequate for the diffusion of family planning information. It was observed that the women in the village with mothers' club have higher level of family planning knowledge and favorable attitude. However, little defference was found in family planning pratice rate between two villages. This may have been resulted from the fact that family planning practice is associated with many other factors than knowledge of and attitude toward contraceptive methods. It should be noted that this study is too limited in scope and scale to obtain general conclusions. This suggests that more extensive study is required to provide information on the nature and mechanism of the impact of mothers' clubs on family planning behavior of village women.

고삼(苦蔘)(Sophorae Radix)의 생체 반응에 대한 연구(I)

강탁림,황귀서,KANG, TAK-LIM,HWANG, GWI-SEO Research Institute of Korean Medicine 1992 한의학연구소 논문집 Vol.1 No.1

청열조습(淸熱燥濕), 거풍살충(祛風殺蟲)의 효능이 있는 고삼(苦蔘)의 체내 면역활성에 미치는 영향에 대해 실험한 결과 아래와 같은 지견을 얻었다. ICR 생쥐에 고삼(苦蔘) 수침액을 투여한 결과 백혈구수 및 면역장기 변화는 없었다. in vitro실험에서 IgM PFCs에 유의성 있는 영향을 주지 못했고, BSA를 주사한 생쥐에서의 Arthus 반응에도 영향이 없었다. 그러나 지연형 과민반응을 억제하였으며, 비특이적 면역에 관여하는 macrophage의 탐식능을 약간 저하시켰다. 이상의 결과 고삼(苦蔘) 수침액(水浸液)은 세포성 면역을 억제하는 것으로 사료된다.

한방병원의 재무적 특성

강탁림,Kang Tak-Lim 대한예방한의학회 1997 대한예방한의학회지 Vol.1 No.1

Despite of increasing market share, oriental hospitals are now facing profit deterioration. In order to contribute to both better policy making of the Government Md corporate planning in the part of the individual hospitals this study attempted to identify the oriental hospital's financial characteristics. financial performance data for 1995, published by the Korea Institute of Health Services Management, were analysed from the structural perspective of patient composition, capital and resources input, medical revenue and costs, and financial efficiency and profitability. Some financial characteristics were drawn based on the results of the analysis. The areas that require corrective action and future study were also suggested.

인체 위암세포주 SNU-1 에 대한 수종 한약재의 항암활성

康坼林 대전대학교 韓醫學연구소 1995 한의학연구소 논문집 Vol.4 No.1

Although significant progress has been made during the past four decades in the treatment of human neoplastic disease, effective chemotherapeutic treatments are nevertheless far from satisfactory to patients suffering from cancer, particularly to those with the stomach cancer which is most prevalent in Korea. To find out the effective anticancer drugs, especially human stomach cancer, we tested cytotoxic activities of several medicinal herbs against human stomach cancer cell line, SNU-1. Evodia officinalis, Melia toosendan, Sinomenium acutum, Galla Haeepensis, Celastrus orbiculatus and Taxus caespitosa showed a significant cytotoxic activities.

가미온담탕(加味溫膽湯)이 스트레스성 뇌신경전달물질(腦神經傳達物質) 변화(變化)에 미치는 영향(影響)

강탁림,Kang Tak-Lim 대한예방한의학회 2001 대한예방한의학회지 Vol.5 No.2

To elucidate the preventive effect of oriental medicine Gami-Ondamtang(GO) on stress, we investigated the physiological change of rats which were applied immobilization stress. For immobilization stress, rats were placed in restrainer for 12 hours a day for 3 days. During application of stress, body weight of rats was measured. After sacrifice, 8 organs were taken for measurement of organ weight. Brain was sectioned into 4 parts that are Frontal Cortex, Corpus Striatum, Hypothalamus and Hippocampus. Each part was homogenated and its catecholamine and serotonin contents were measured with HPLC. In our study, stress mainly induced increase of concentration of neurotransmitters in brain without other significant physical change of rats. GO inhibited stress induced changes of neurotransmitter content in brain.

한방병원 입원한자의 진료과별 및 재원일별 평균진료비의 분포적 특성

강탁림,Kang Tak-Lim 대한예방한의학회 2000 대한예방한의학회지 Vol.4 No.1

This study was performed to find out characteristics of daily average medical charge of the inpatients of an oriental medical university hospital in TaeJeon. The sample of the study was 966 inpatients discharged from the 4 clinical departments of th hospital from January 1 to June 31, 1998. The major findings are as follows : 1. The average length of stay was 15.6 days in dept. of Internal Medicine, 16.9 in Acupuncture, 10.1 in Neuro-psychiatry and 24.3 in Physical therapy Daily average medical charge of the depart ments was 70,517 Won 62,011 Won, 82,750Won and 65,390 Won respectively. 2. The daily average medical charge of the departments was highest in the first day of admission. From the second day, it maintained a lower and relatively constant level, but showing slight fluctation in the latter halt of the hospital stay.

數種 漢藥材의 抗癌活成 硏究

康坼林 대전대학교 韓醫學연구소 1995 한의학연구소 논문집 Vol.3 No.2

[15-03] An extensive anticancer drug screening from natural resources has been carried out primarily using murine tumor model for past fourty years. Recently a new screening program from NCI, so called disease-oriented screening system, has been estabished to detect anticancer drugs that show selective growth inhibition toward variety of tissue specific human solid tumors originated from leukemia, lung, colon, CNS, melanoma, ovarian, renal, prostate amd breast. To develope the anticancer drugs from oriental medicinal herbs, we investigated the cytotoxic effects against human tumor cell panels with 23 kinds of MeOH extract of medicinal herbs. Evodiae Fructus, Meliae Toosendan Fructus, Saussureae Radix and Pharbitidis Semen showed strong activities against several tumor cell lines.

지유의 수치에 관한 연구 -볶은 지유로부터 불리된 토멘토솔린산-

강탁림(Tak Lim Kang),박만기(Man Ki Park) 대한약학회 1994 약학회지 Vol.38 No.6

Some traditional herbal drugs have been used after processing to modify its activities. For example, roasted "chiyu"(Sanguisorbae radix) has been used as antihemorrhagics while raw one used as anti-emetics. The composition of herbal drug is expected to be changed during this process. We tried to reveal the compositional difference between raw and roasted "chiyu", and isolated a compound which is not present in raw one but in processed one. The structure of the isolated compound was elucidated as tomentosolic acid. The content of tomentosolic acid in roasted "chiyu" was approximately 0.05%.

어머니會가 이웃 사이의 家族計劃 코뮤니케이숀 樣相에 미친 影響에 對한 事例硏究

康坼林(Tak Lim Kang) 서울대학교 보건환경연구소 1976 보건학논집 Vol.13 No.1