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- 저자 : 강종술 (검색결과 2 건)
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강종술,김규정,서범석,이종수,이현성 대한신경외과학회 2004 Journal of Korean neurosurgical society Vol.35 No.4
Objective : The author evaluate the efficacy of surgery, radiation therapy and chemotherapy as a treatment methods for anaplastic oligodendroglioma patients to provide the standardized treatment option. Methods : A retrospective analysis of ten pathologically proven cases of anaplastic oligodendroglioma was performed. Results : The ten patients comprised four males and six females. The mean age at diagnosis was 34.4 year(8-70). The mean follow-up was 40.5 months, and two patients died of tumor progression during the follow-up(70, 86 months, respectively). All patients had craniotomy and the tumors were removed as much as possible. The tumos were resected totally in five cases, only subtotally in the rest. Radiation therapy was applied to seven patients, and PCV(procarbazine-CCNU-vincristine) based chemotherapeutic agent was administered to five patients. In the group with PCV therapy, complete remission was observed in two, partial remission was in one, stable disease in one, and disease progression in one who were died of tumor extension. During the follow-up, tumor recurrences were observed in four patients, and they were treated with additional operation and/or chemotherapy. Conclusion : Anaplastic oligodendrogliomas respond to the surgical and radiological treatment and especially to the chemotherapy, and have a relatively good prognosis. PCV is an effective and safe regimen for suppressing tumor growth, and is feasible for recurrent cases. PCV chemotherapy should be considered for primary treatment method for anaplastic oligodendroglioma patients.
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김규정,강종술,서범석,이현성,이종수 대한신경외과학회 2003 Journal of Korean neurosurgical society Vol.33 No.2
Objective:The goal of this study is to establish the value of the programmable valve system. Methods:The authors conducted a single center retrospective study of 41 consecutive patients who had undergone ventriculoperitoneal shunt with programmable valve for hydrocephalus of various etiology from March 1999 to February 2002. Results:In 10 patients(24%), valve pressure adjustment was required at least 3 times or more for the reason of underdrainage or overdrainage. The range of pressure reprogramming was 10 to 120mmH2O. The clinical symptoms improved in 37 patients(90%). The radiologic improvement was obtained in 88%. Shunt was minimally functioning in 3 cases without any clinical effect at the pressure of 30mmH2O. Conclusion:The programmable valve has been particularly useful in changing ventricular size for the correction of overdrainage or underdranage by the easy control of valve pressure without any invasive procedure. The authors' preference is to use the programmable valve system for all conditions. Key words:Hydrocephalus;Programmable valve;Overdrainage;Underdrainage.
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