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임신 혈청의 Concanavaline A - 억제성 5`-Nucleotidase
문병갑(BK Moon),장향모(HM Chang) 대한산부인과학회 1979 Obstetrics & Gynecology Science Vol.22 No.10
Concanvaline A(Con A) which strongly inhibits human placental 5-nucleotidase also showed an inhibitory effect upon AMP hydrolysis by serum of a pregant woman. In contrast, Con A did not exert any effect upon serum heat-stable alkaline phosphatase of a pregnant woman. Comparison of serum Con A-inhibitable 5-nucleotidase activity between 6 cases of normal non-pregnant and 11 cases of pregnant woman at the 40-weeks gestation showed a significant rise of the enzyme activity during pregnancy. The possibility that the serum Con A-inhibitable 5-nucleotidase may be originated from the placenta during pregnancy as in the case of serum heat-stable alkaline phosphatase was discussed.