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      • Dynamic Analysis of Catapult Availability Based on CBM

        Xia Guo-Qing,Luan Tian-Tian,Sun Ming-Xiao,Liu Yan-Wen 보안공학연구지원센터 2016 International Journal of Hybrid Information Techno Vol.9 No.10

        The repair of catapult is a complicated engineering. In this paper, the method of Condition Based Maintenance is applied into the repair system based on the catapult maintenance of system analysis. In view of the application of Condition Based Maintenance in the modern aviation equipment, the catapult availability is the final goal. The structure of catapult maintenance system is analyzed. The structure model of system dynamic feedback is established by using system dynamics method. Simulation is based on the "Nimitz" actual data of the Surge operation in 1997. The results prove the effectiveness and rationality of the proposed method. Through the analysis of the simulation evaluation results, the method applying Condition Based Maintenance into catapult repair system can improve catapult availability.

      • KCI우수등재

        Dual Effect of Hepatic Macrophages on Liver Ischemia and Reperfusion Injury during Liver Transplantation

        Tian-Fei Lu,Tai-Hua Yang,Cheng-Peng Zhong,Chuan Shen,Wei-Wei Lin,Guang-Xiang Gu,Qiang Xia,Ning Xu 대한면역학회 2018 Immune Network Vol.18 No.3

        Ischemia-reperfusion injury (IRI) is a major complication in liver transplantation (LT) and it is closely related to the recovery of grafts' function. Researches has verified that both innate and adaptive immune system are involved in the development of IRI and Kupffer cell (KC), the resident macrophages in the liver, play a pivotal role both in triggering and sustaining the sterile inflammation. Damage-associated molecular patterns (DAMPs), released by the initial dead cell because of the ischemia insult, firstly activate the KC through pattern recognition receptors (PRRs) such as toll-like receptors. Activated KCs is the dominant players in the IRI as it can secret various pro-inflammatory cytokines to exacerbate the injury and recruit other types of immune cells from the circulation. On the other hand, KCs can also serve in a contrary way to ameliorate IRI by upregulating the anti-inflammatory factors. Moreover, new standpoint has been put forward that KCs and macrophages from the circulation may function in different way to influence the inflammation. Managements towards KCs are expected to be the effective way to improve the IRI.

      • Mitochondrial DNA Levels in Blood and Tissue Samples from Breast Cancer Patients of Different Stages

        Xia, Peng,Wang, Hui-Juan,Geng, Ting-Ting,Xun, Xiao-Jie,Zhou, Wen-Jing,Jin, Tian-Bo,Chen, Chao Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.3

        Aims: Alterations in mitochondrial DNA (mtDNA) have been implicated in carcinogenesis and tumor progression. We here evaluated the diagnostic and prognostic potential of mtDNA as a biomarker for breast cancer. Methods: Using multiplex real-time polymerase chain reaction, nuclear DNA (nDNA) and mtDNA levels in serum, buffy coat, tumor, and tumor-adjacent tissue samples from 50 breast cancer patients were determined and assessed for associations with clinicopathological features. To evaluate mtDNA as a biomarker for distinguishing between the four sample types, we created receiver operating characteristic (ROC) curves. Results: The mtDNA levels in buffy coat were significantly lower than in other sample types. Relative to tumor-adjacent tissue, reduced levels of mtDNA were identified in buffy coat and tumor tissue but not in serum. According to ROC curve analysis, mtDNA levels could be used to distinguish between buffy coat and tumor-adjacent tissue samples with good sensitivity (77%) and specificity (83%). Moreover, mtDNA levels in serum and tumor tissue were positively associated with cancer TMN stage. Conclusions: The mtDNA levels in blood samples may represent a promising, non-invasive biomarker in breast cancer patients. Additional, large-scale validation studies are required to establish the potential use of mtDNA levels in the early diagnosis and monitoring of breast cancer.

      • The G801A Polymorphism in the CXCL12 Gene and Risk of Breast Carcinoma: Evidence from a Meta-Analysis Including 2,931 Subjects

        Xia, Yong,Guo, Xu-Guang,Ji, Tian-Xing Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.6

        More and more evidence indicates that the G801A polymorphism in the CXCL12 gene might be associated with susceptibility to breast carcinoma in humans being. However, individually published results have been inconsistent. The purpose of this meta-analysis was to investigate the association between the G801A polymorphism in the CXCL12 gene and breast carcinoma risk. A complete search strategy was done by the electronic databases including PubMed and Chinese Biomedical Literature Database. A meta-analysis including seven individual studies was carried out in order to explore the association between the G801A polymorphism in the CXCL12 gene polymorphisms and breast carcinoma. The pooled odds ratios (ORs) and their corresponding 95% confidence intervals (95%CIs) between the G801A polymorphism in the CXCL12 gene and breast carcinoma risk were assessed by the random-effects model. A significant relationship between the G801A polymorphism in the CXCL12 gene and breast carcinoma was discovered in an allelic genetic model (OR: 1.214, 95%CI: 1.085-1.358, p=0.001), a homozygote model (OR: 1.663, 95%CI: 1.240-2.232, p=0.001), a heterozygote model (OR: 1.392, 95%CI: 1.190-1.629, p=0.000), a recessive genetic model (OR: 1.407, 95%CI: 1.060-1.868, p=0.018) and a dominant genetic model (OR: 1.427, 95%CI: 1.228-1.659, p=0.000). On sub-group analysis based on ethnicity, significance was observed between the European group and the mixed group. A significant relationship was found between the G801A polymorphism in the CXCL12 gene and breast carcinoma risk. Individuals with the A allele of the G801A polymorphism in the CXCL12 gene are under a higher risk for breast carcinoma.

      • SCIESCOPUSKCI등재

        Modified Asymmetrical Variable Step Size Incremental Conductance Maximum Power Point Tracking Method for Photovoltaic Systems

        Tian, Yong,Xia, Bizhong,Xu, Zhihui,Sun, Wei The Korean Institute of Power Electronics 2014 JOURNAL OF POWER ELECTRONICS Vol.14 No.1

        The power-voltage (P-V) characteristic of a photovoltaic (PV) array is nonlinear and time varying with the change in atmospheric conditions. As a result, the maximum power point tracking (MPPT) technique must be applied in PV systems to maximize the generated energy. The incremental conductance (INC) algorithm, one of the MPPT strategies, is widely used for its high tracking accuracy, good adaptability to rapidly changing atmospheric conditions, and easy implementation. This paper presents a modified asymmetrical variable step size INC MPPT method that is based on the asymmetrical feature of the P-V curve. Compared with conventional fixed or variable step size method, the proposed method can effectively improve tracking accuracy and speed. The theoretical foundation and design principle of the proposed approach are validated by the simulation and experimental results.

      • SCIESCOPUS

        Structural damage detection by principle component analysis of long-gauge dynamic strains

        Xia, Q.,Tian, Y.D.,Zhu, X.W.,Xu, D.W.,Zhang, J. Techno-Press 2015 Structural Engineering and Mechanics, An Int'l Jou Vol.54 No.2

        A number of acceleration-based damage detection methods have been developed but they have not been widely applied in engineering practices because the acceleration response is insensitive to minor damage of civil structures. In this article, a damage detection approach using the long-gauge strain sensing technology and the principle component analysis technology is proposed. The Long gauge FBG sensor has its special merit for damage detection by measuring the averaged strain over a long-gauge length, and it can be connected each other to make a distributed sensor network for monitoring the large-scale civil infrastructure. A new damage index is defined by performing the principle component analyses of the long-gauge strains measured from the intact and damaged structures respectively. Advantages of the long gauge sensing and the principle component analysis technologies guarantee the effectiveness for structural damage localization. Examples of a simple supported beam and a steel stringer bridge have been investigated to illustrate the successful applications of the proposed method for structural damage detection.

      • SCIESCOPUS

        Preparation of Co<sub>3</sub>O<sub>4</sub>/NF Anode for Lithium-ion Batteries

        Tian, Shiyi,Li, Botao,Zhang, Bochao,Wang, Yang,Yang, Xu,Ye, Han,Xia, Zhijie,Zheng, Guoxu The Korean Electrochemical Society 2020 Journal of electrochemical science and technology Vol.11 No.4

        Due to its characteristics of light weight, high energy density, good safety, long service life, no memory effect, and environmental friendliness, lithium-ion batteries (LIBs) are widely used in various portable electronic products. The capacity and performance of LIBs largely depend on the performance of electrode materials. Therefore, the development of better positive and negative materials is the focus of current research. The application of metal organic framework materials (MOFs) derivatives in energy storage has attracted much attention and research. Using MOFs as precursors, porous metal oxides and porous carbon materials with controllable structure can be obtained. In this paper, rod-shaped Co-MOF-74 was grown on Ni Foam (NF) by hydrothermal method, and then Co-MOF-74/NF precursor was heat-treated to obtain rodshaped Co<sub>3</sub>O<sub>4</sub>/NF. Ni Foam was skeleton structured, which effectively relieved. The change of internal stress changes and destroys the structural volume of the electrode material and reduces the capacity attenuation. Co<sub>3</sub>O<sub>4</sub>/NF composite material has a specific discharge capacity of up to 1858 mA h/g for the first time, and a reversible capacity of up to 902.4 mA h/g at a current density of 200 mA/g, and has excellent rate and impedance performance. The synthesis strategy reported in this article opens the way to design high-performance electrodes for energy storage and electrochemical catalysis.

      • KCI등재

        Acupuncture for Osteoporosis: a Review of Its Clinical and Preclinical Studies

        Tian Yimiao,Wang Lili,Xu Tianshu,Li Rui,Zhu Ruyuan,Chen Beibei,Zhang Hao,Xia Bingke,Che Yiwen,Zhao Dandan,Zhang Dongwei 사단법인약침학회 2022 Journal of Acupuncture & Meridian Studies Vol.15 No.5

        Acupuncture has gained growing attention in the management of osteoporosis (OP). However, a comprehensive review has not yet been conducted on the efficacy and challenges of acupuncture in preliminary research and clinical trials. Therefore, an extensive literature search was conducted using electronic databases, including PubMed (www.ncbi.nlm.nih.gov/pubmed), CNKI (www.cnki.net), and Web of Science, for studies published from the beginning of 2000 to the end of May 2022. Combinations of synonyms for OP, acupuncture, traditional Chinese medicine, clinical trial, preclinical study, and animal experiments were searched. A total of 290 papers were consulted, including 115 reviews, 109 clinical observations, and 66 preclinical studies. There is accumulating evidence to support the beneficial role of acupuncture in preserving bone quality and relieving clinical symptoms based on clinical and preclinical investigations. The top ten most commonly used acupoints are BL23, ST36, BL20, BL11, CV4, GV4, SP 6, KI3, BL18, and GB39. The underlying mechanisms behind the benefits of acupuncture may be linked with the regulation of the hypothalamic-pituitary-gonadal (adrenal) axis and activation of the Wnt/β-catenin and OPG/RANKL/RANK signaling pathways. In summary, strong evidence may still come from prospective and well-designed clinical trials to shed light on the potential role of acupuncture in preserving bone loss. Future investigations are needed to explore the potential underlying mechanisms, long-term clinical efficacy, and compliance of acupuncture in OP management.

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