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Risk Factors and Clinical Outcomes of Acute Hypoxemic Respiratory Failure in Patients with Sepsis
( Eunhye Bae ),( Jimyung Park ),( Jaeyoung Cho ),( Nakwon Kwak ),( Sun Mi Choi ),( Jinwoo Lee ),( Young Sik Park ),( Chang-Hoon Lee ),( Chul-gyu Yoo ),( Sang-min Lee ) 대한결핵 및 호흡기학회 2021 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.129 No.-
Purpose Sepsis may act as an important predisposing factor in the development of acute hypoxemic respiratory failure (AHRF). We aimed to evaluate the risk factors for developing AHRF in patients with sepsis and assess clinical outcome. Methods We conducted a secondary analysis of nationwide multicenter prospective observational cohort enrolled from September 2019 to February 2020. Adult patients who admitted to ICU with sepsis were included. Multivariate logistic regression modeling was used to identify risk factors associated with AHRF, defined as PaO2/FiO2 ratio < 300 and receiving invasive mechanical ventilation within 24 hours of admission to the ICU. We used Kaplan-Meier survival analysis to compare survival within 28-day between two groups. Furthermore, a multivariate logistic regression analysis was also performed to predict ICU mortality and in-hospital mortality. Results 901 patients with sepsis were enrolled, whom 316 (35%) patients developed AHRF. In multivariable logistic regression, lactate (adjusted OR 1.08; 95% CI, 1.03-1.13), initial sequential organ failure assessment (SOFA) score (1.09; 95% CI, 1.03-1.14), pulmonary origin sepsis (3.69; 95% CI, 2.66-5.14) and septic shock (1.56; 95% CI, 1.12-2.16) were risk factors for the development of AHRF in patients with sepsis. 28-day mortality and in-hospital mortality were significantly increased when AHRF was present in patients with sepsis (adjusted OR 2.04; 95% CI, 1.49-2.80 and 2.06; 95% CI 1.52-2.80, respectively). Conclusions Lactate, initial SOFA score, pulmonary origin sepsis and septic shock were found to be risk factors of AHRF in patients with sepsis. In addition, the clinical outcome was worse when AHRF was combined in sepsis.
Hydrogeochemical Background of a Tracer Test Site for Evaluating Buffering Capacity
Eunhye Kwon,Byeong-hak Park,Kyung-woo Park 한국방사성폐기물학회 2023 한국방사성폐기물학회 학술논문요약집 Vol.21 No.2
In the evaluation of the stability of radioactive waste disposal, it is imperative to take into account the concept of the redox front. Initially, this front is typically observed near the surface. However, if the hydraulic gradient increases due to the construction of a disposal facility, the redox front can potentially transport deeper into the geological environment through groundwater flow. This transport triggers changes in the geochemical characteristics, potentially diminishing the natural buffering capacity of the bedrock. Consequently, it is necessary to characterize both the unsaturated and saturated zones in the disposal site. In this context, a tracer test is a useful method to identify the characteristics of the site from the surface to the deep geological environment where the disposal facility can be located. Therefore, this study also aims to establish a methodology enabling a comprehensive understanding of the hydrogeochemical characteristics through the tracer test that can be applied to future sites for research URL (Underground Research Laboratory) or radioactive waste disposal in Korea. For the tracer test, a UNIT (UNsaturated zone Insitu Test facility) was built within the KAERI and five wells with a depth of 24 m were installed in 2022. Before conducting the test, to determine the geochemical background characteristics of the site, topsoil and soils at depths of 30 cm, 60 cm, and 90 cm were collected. Additionally, a groundwater sample was obtained from the newly installed well. Soil samples were analyzed for soil texture, moisture content, total and exchange cations, anions, and heavy metals. Similarly, the groundwater sample was analyzed for cations, anions, and trace elements. The outcomes of these comprehensive analyses will serve as the baseline values in the hydrogeochemical changes after the tracer test. This includes changes in soil composition, water quality, precipitation/dissolution processes, and mineral phases. Furthermore, these results will be provided as input parameters for surface-underground interface models in future studies.
( Eunhye Cho ),( Sung Yob Kim ),( Chul Min Park ),( Soon Seop Sim ),( Hae Sim Kang ),( Soyun Park ),( Soo Jung Kim ),( Seong-cheol Hong ) 대한산부인과학회 2018 대한산부인과학회 학술대회 Vol.104 No.-
Objective: There is few studies compared standard abdominal sacrocolpexy and the laparoscopic approach for POP patient with uterus. We aim to compare the therapeutic effect of laparoscopic and abdominal sacrocolpopexy . Methods: We performed retrospective study comparing abdominal sacrocolpopexy and laparoscopic sacrocolpopexy in single university hospital in Jeju island, South Korea. We collected sacrocolpopexy surgery case from July 2008 to December 2017. Total number of case was 183 and we selected 120 cases performed by single operator. Among them, we excluded vault prolapse and total 105case were compared. Because all of the cases were performed by single operator, pre-operative and post-operative treatment were almost same through whole case. The collected data was analyzed by using statistics package SPSS version 2. Results: The characteristics of patients were almost same between the two group. Parity was the only different parameter. But it may affect pre-op POP stage or severity of disease, so we didnt give meaning. Estimated blood loss during the operation was smaller and operation time was shorter in the laparoscopic sacrocolpopexy group. Number of complication was indifferent between two group. Conclusion: Our trial provides evidence to support a laparoscopic approach when performing sacrocolpopexy, as there was less blood loss and operation time was shorter, whereas complication was not statistically different. A strength of this study is that whole perioperative care was identically done for all patient.
Comparison of Evapotranspiration Estimated Using Simple and Complex Models
Eunhye Kwon,Byeong-hak Park,Kyung-woo Park 한국방사성폐기물학회 2023 한국방사성폐기물학회 학술논문요약집 Vol.21 No.1
Surface environmental factors such as climate change can affect the safety of the disposal system by changing groundwater recharge or flow. Therefore, it is important to identify surface environmental factors and hydrogeological factors to evaluate long-term changes in hydrogeological environment of a disposal system. In particular, evapotranspiration is an important to be considered because it loses 70% of rainfall and has a great effect on groundwater recharge. Evapotranspiration can be estimated using simple or complex models based on meteorological data. Meteorological data from January 2010 to December 2022 were collected from 44 Automatic Synoptic Observation Systems (ASOS) of the Korea Meteorological Administration (KMA), which observe factors necessary for calculating evapotranspiration. For the estimation of evapotranspiration through simple models, temperature-based models (Blaney-Criddle method, modified Blaney-Criddle method, Hargreaves-Samani method) and radiation-based models (Simple Abtew method, Makkink method, Prietley-Taylor method, Turc method, Solar radiation-Maximum temperature method) were used. The calculation of evapotranspiration through the complex model used the Penman-Monteith method, which is used as a standard model in the USA, Japan, and FAO. By comparing the evapotranspiration calculated by complex and simple model, methods with small errors were identified each region. In addition, long-term climate change scenarios were applied to confirm changes in long-term evapotranspiration in South Korea. The results of this study will be used to find alternative models in the case of missing data in the Penman-Monteith model, which requires a lot of meteorological data, and can be used as basic data for calculating groundwater recharge that can affect the disposal system in the future.
Park, Song Hee,Lee, Hwa Sung,Kim, Jong-Dae,Breiby, Dag W.,Kim, Eunhye,Park, Yeong Don,Ryu, Du Yeol,Lee, Dong Ryeol,Cho, Jeong Ho Royal Society of Chemistry 2011 Journal of materials chemistry Vol.21 No.39
<P>We investigated the crystalline nanostructures and film morphologies of pentacene films deposited onto a polymer brush organic interlayer in high performance organic field-effect transistors (OFETs). Polymer brushes were grafted onto the oxide substrates by spin-coating and thermal annealing. Pentacene FETs fabricated on top of the polymer brushes showed excellent device performance, with a field-effect mobility of 0.82 cm<SUP>2</SUP> V<SUP>−1</SUP> s<SUP>−1</SUP> and an on/off current ratio of 10<SUP>7</SUP>. These properties were superior to those of devices using typical surface modification techniques, such as octadecyltrichlorosilane (ODTS) and hexamethyldisilazane (HMDS). The improvements in OFET performance appeared to be due to the pentacene layer's crystalline nanostructure and grain interconnectivity, which formed during the submonolayer stage of film growth. This stage of growth is strongly correlated with the surface energy, morphology, and viscoelastic properties of the resulting gate dielectrics. The inclusion of a polymer brush dielectric surface modification is a significant step toward optimizing the nanostructures of organic semiconductors, which are directly linked to device performance enhancement, by engineering the interfaces in OFETs.</P> <P>Graphic Abstract</P><P>The inclusion of a polymer brush dielectric surface modification is a significant step toward optimizing the nanostructures of organic semiconductors, which are directly linked to device performance enhancement. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c1jm11607j'> </P>
An Efficient Time-Shifted Random Access Scheme for Cellular-Based IoT Networks
Park, Eunhye,Kim, Taehoon,Han, Youngnam IEEE 2019 IEEE communications letters Vol.23 No.3
<P>Random access (RA) scheme is one of the critical issues for successfully and efficiently connecting devices in the Internet of Things (IoT) networks. In cellular-based IoT networks, Zadoff–Chu (ZC) sequences are used as preambles, where their cyclically shifted versions are orthogonal to each other. We propose a time-shifted RA scheme for cellular IoT networks to reduce collision and to accommodate more devices, which can also increase fairness. In the proposed scheme, each IoT device efficiently adjusts the amount of cyclic shift of ZC sequences during preamble generation phase. We formulate an optimization problem to minimize average collision probability and provide an algorithmic solution. Simulation reveals that our proposed scheme can achieve near-perfect fairness while effectively mitigating collision probability.</P>