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Leisure Time Physical Activity in Saudi Arabia: Prevalence, Pattern and Determining Factors
Amin, Tarek Tawfik,Al Khoudair, Ali Salah,Al Harbi, Mohammad Abdulwahab,Al Ali, Ahmed Radi Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.1
Background: Identification of reliable predictors of leisure time physical activity (LTPA) will enable healthcare providers to intervene and change the patterns of LTPA in the population to improve community health. Objectives: The objectives of this study were to determine prevalence and pattern of LTPA among adult Saudis aged 18-65 years, and to define the socio-demographic determinants that correlate with LTPA in Al-Hassa, Saudi Arabia. Subjects and Methods: A cross-sectional study of 2176 adult Saudis attending urban and rural primary health care centers were selected using a multistage proportionate sampling method. Participants were personally interviewed to gather information regarding socio-demographics, physical activity pattern using the Global Physical Activity Questionnaire (GPAQ). Physical activity (PA) in each domain was expressed in metabolic equivalents (METs). Results: The median total METs minutes/week for LTPA for both genders was 256, higher for men (636 METs minutes/week) compared to women (249METs minutes/week). Overall, only 19.8% of the total PA was derived from LTPA. Of the sampled population 50.0% reported doing no leisure activity. Using the cut off of 600 METs-minutes/day or 150 minutes of moderate intensity over 5 or more days/week, only 21.0% of the included sample were considered as being sufficiently active and 10.4% were in the high active category with beneficial health effects. Multivariate regression analysis showed that male, younger age (<35 years), absence of chronic disease conditions and moderate level of total PA were significant predictors for being active in the LTPA domain. Conclusion: The prevalence and intensity of LTPA among the included sample demonstrated low levels. Nearly 80% of the included sample population did not achieve the recommended LTPA level with beneficial health effects. Female gender, urban residence and associated chronic diseases correlated with a low LTPA.
( Jamal Al Wakeel ),( Ziyad Makoshi ),( Mohammed Al Ghonaim ),( Ali Al Harbi ),( Abdulkareem Al Suwaida ),( Farjah Algahtani ),( Mogbil Al Hedaithy ),( Sultan Almogairin ),( Sami Habiballa Abdullah ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background: Mycobacterium tuberculosis infection is the result of large number of morbidity and mortality worldwide. Saudi Arabia has an incidence rate ranged between8.6 and 12.2/100,000. QuantiFERON-TB Gold in-tube is approved to detect latent tuberculosis infection and TB disease. We conduct this study to estimate the prevalence of latent Tuberculosis in healthy population in Saudi Arabia and detect the sensitivity, specifi city and positive and negative predictive values for QuantiFERON-TB Gold in-tube. Methods: A cross-sectional study of blood sampling for QuantiFERON-TB Gold intube testing took from healthy blood donor were recruited from blood bank at King Saud University (KSU) and volunteers from Riyadh region, with further contact and follow up for positive results for two years for activation of latent tuberculosis. The study supported by King Saud University and King Abdul-Aziz City for Science and Technology. Project number ARP-245-29. Results: The study consists of 563 participants, their mean age was 34.2±13.17 year, 292 (51.9 %) male and mean BMI was 27.5 ±5.53 kg/m2. 363 (65.6%) had a BCG scar, the contact to the TB patients represented by 33 (5.9%) and 7 (1.2%) had a previous TB infection. Positive result for QFT-GIT was found in 72 (12.8%) participants, 48 (69.6%) of them had a BCG scar, only 2 (2.8%) and 4 (5.6%) had history of previous TB and contact of TB patients, respectively. Our study showed sensitivity of 90.62% (75-98%) and specificity of 91.53% (89-94%) with a positive predictive value of 39.19% (28-51%) and negative predictive value of 99.39% (98-99.9%) Conclusions: In face of reduction of the limits of other technique, QFT-GIT is not a signifi cant in diagnosis of latent TB. However, it is signifi cant in ruling out the presence of disease.
Aldahmash, Abdullah,Atteya, Muhammad,Elsafadi, Mona,Al-Nbaheen, May,Al-Mubarak, Husain Adel,Vishnubalaji, Radhakrishnan,Al-Roalle, Ali,Al-Harbi, Suzan,Manikandan, Muthurangan,Matthaei, Klaus Ingo,Mahm Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.10
Background: Embryonic stem cells (ESCs) have the potential to form teratomas when implanted into immunodeficient mice, but data in immunocompetent mice are limited. We therefore investigated teratoma formation after implantation of three different mouse ESC (mESC) lines into immunocompetent mice. Materials and Methods: BALB/c mice were injected with three highly germline competent mESCs (129Sv, BALB/c and C57BL/6) subcutaneously or under the kidney capsule. After 4 weeks, mice were euthanized and examined histologically for teratoma development. The incidence, size and composition of teratomas were compared using Pearson Chi-square, t-test for dependent variables, one-way analysis of variance and the nonparametric Kruskal-Wallis analysis of variance and median test. Results: Teratomas developed from all three cell lines. The incidence of formation was significantly higher under the kidney capsule compared to subcutaneous site and occurred in both allogeneic and syngeneic mice. Overall, the size of teratoma was largest with the 129Sv cell line and under the kidney capsule. Diverse embryonic stem cell-derived tissues, belonging to the three embryonic germ layers, were encountered, reflecting the pluripotency of embryonic stem cells. Most commonly represented tissues were nervous tissue, keratinizing stratified squamous epithelium (ectoderm), smooth muscle, striated muscle, cartilage, bone (mesoderm), and glandular tissue in the form of gut- and respiratory-like epithelia (endoderm). Conclusions: ESCs can form teratomas in immunocompetent mice and, therefore, removal of undifferentiated ESC is a pre-requisite for a safe use of ESC in cell-based therapies. In addition the genetic relationship of the origin of the cell lines to the ability to transplant plays a major role.