‘Horse’ as A Symbol Reflected from Cultural Memory in The Poem Called At (The Horse) of Faruk Nafiz Çamlıbel

Ahmet Demir,Nilgün Çelik 고려대학교 응용문화연구소 2023 에피스테메 Vol.- No.29

Culture, which can be defined as the lifestyle of a nation, is the sum and whole of social experiences and learning. Considering the connotations of the concept of memory such as storage and preservation, it is possible to say that cultural memory provides the continuity of cultural elements in an impersonal area. Cultural memory, with its dynamic structure, includes actions such as “recollection, ‘repetition’ and ‘reviving/keeping alive’ in ensuring the continuity of cultural elements. Literary texts from oral culture to written culture often include these actions by fulfilling a formant function. Therefore, considering literary texts as reflection areas of cultural memory and making analyzes on cultural elements and symbols is one of the text analysis methods. In Turkish culture, ‘horse’ is an important cultural element. As a result of the living conditions brought by the steppe culture in the Turks, the ‘horse’ has become an important part of life and has become one of the main figures of cultural memory in relation to many emotions, thoughts and dreams. Even the existence of many idioms and proverbs about horse in Turkish alone explains the place of horse in cultural memory. Also, horse is one of the cultural symbols that is repeated in many oral, written and visual texts and in various branches of art, and remains alive as it is repeated. Faruk Nafiz Çamlıbel (1898-1973) used horse allegorical in relation to the Turkish nation in his poem called At (The Horse) (1919), which he wrote during the War of Independence, one of the milestones in Turkish history. In the poem, the horse appears with a symbolism that represents the Turkish nation and the ‘independent’ character of the Turkish nation with references to the historical conditions of the First World War (1914-1918) and War of Independence (1919-1923). In this context, in this study, poem called The Horse of Faruk Nafiz Çamlıbel is considered as a cultural memory area and horse is examined as a ‘cultural symbol’. The image of horse drawn in the poem is examined in historical and socio-cultural dimensions and evaluated in the context of the place of horse in Turkish culture.

Durability of Sustained Virologic Response in Chronic Hepatitis C

( Ahmet Uyanikoglu ),( Sabahattin Kaymakoglu ),( Ahmet Danalioglu ),( Filiz Akyuz ),( Fatih Ermis ),( Binnur Pinarbasi ),( Kadir Demir ),( Fatih Besisik ),( Yilmaz Cakaloglu ) 대한소화기학회 2013 Gut and Liver Vol.7 No.4

Background/Aims: The aim of this study is to investigate the rate of sustained virologic response (SVR) in chronic hepatitis C patients receiving antiviral treatment. Methods: The files of patients with chronic hepatitis C treated with interferon±ribavirin between 1995 and 2009 were reviewed retrospectively. Six months after the end of treatment, patients with negative hepatitis C virus (HCV)-RNA (<50 IU/mL, as determined by the polymerase chain reaction method) were enrolled in the study. Results: The mean age of 196 patients (89 males) was 46.13±11.10 years (range, 17 to 73 years). In biopsies, the mean stage was 1.50±0.94; histological activity index was 7.18±2.43. In total, 139 patients received pegylated interferon (IFN) +ribavirin, 21 patients received classical IFN+ribavirin, and 36 patients received IFN alone. The HCV genotypes of 138 patients were checked: 77.5% were genotype 1b, and 22.5% were other genotypes. After achievement of SVR, the median follow-up period was 33.5 months (range, 6 to 112 months), and in this period relapse was only detected in two patients (1.02%) at 18 and 48 months after treatment. Conclusions: In total, 98.9% of patients with SVR in chronic hepatitis C demonstrated truly durable responses over the long-term follow-up period of 3 years; relapsed patients had intermittent or low-grade viremia. (Gut Liver 2013; 7:458-461)

INVESTIGATION OF LEACHATE RECIRCULATION EFFECT IN SANITARY LANDFILL SITE

( Ahmet Demir ),( Adem Baştürk ),( Bestamin Özkaya ),( M. Sinan Bilgili ) 한국폐기물자원순환학회 2002 APLAS Vol.2002 No.1

In this study, the effect of leachate recirculation on waste stabilization was investigated at Odayeri Sanitary Landfill, which locates in the European side of Istanbul. For this purpose, 1,5 hectares (test area) of the landfill area (Odayeri), and two test cells with the dimensions of 25×50×5 m. were used. Vertical injection wells method was used at test area, and surface drainage method was used at test cells for leachate recirculation. Findings obtained from this study are evaluated.

Uplift response of multi-plate helical anchors in cohesive soil

Demir, Ahmet,Ok, Bahadir Techno-Press 2015 Geomechanics & engineering Vol.8 No.4

The use of helical anchors has been extensively beyond their traditional use in the electrical power industry in recent years. They are commonly used in more traditional civil engineering infrastructure applications so that the advantages of rapid installation and immediate loading capability. The majority of the research has been directed toward the tensile uplift behaviour of single anchors (only one plate) by far. However, anchors commonly have more than one plate. Moreover, no thorough numerical and experimental analyses have been performed to determine the ultimate pullout loads of multi-plate anchors. The understanding of behavior of these anchors is unsatisfactory and the existing design methods have shown to be largely inappropriate and inadequate for a framework adopted by engineers. So, a better understanding of helical anchor behavior will lead to increased confidence in design, a wider acceptance as a foundation alternative, and more economic and safer designs. The main aim of this research is to use numerical modeling techniques to better understand multi-plate helical anchor foundation behavior in soft clay soils. Experimental and numerical investigations into the uplift capacity of helical anchor in soft clay have been conducted in this study. A total of 6 laboratory tests were carried out using helical anchor plate with a diameter of 0.05 m. The results of physical and computational studies investigating the uplift response of helical anchors in soft clay show that maximum resistances depend on anchor embedment ratio and anchor spacing ratio S/D. Agreement between uplift capacities from laboratory tests and finite element modelling using PLAXIS is excellent for anchors up to embedment ratios of 6.

Does Immunohistochemistry Provide Additional Prognostic Data in Gastrointestinal Stromal Tumors?

Demir, Lutfiye,Ekinci, Nese,Erten, Cigdem,Kucukzeybek, Yuksel,Alacacioglu, Ahmet,Somali, Isil,Can, Alper,Dirican, Ahmet,Bayoglu, Vedat,Akyol, Murat,Cakalagaoglu, Fulya,Tarhan, Mustafa Oktay Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.8

Background: To investigate the predictive and prognostic effects of clinicopathologic and immunohistochemical (IHC) features in patients with gastrointestinal stromal tumours (GISTs). Materials and Methods: Fifty-six patients who were diagnosed with GIST between 2002 and 2012 were retrospectively evaluated. Relationships between clinicopathologic/immunohistochemical factors and prognosis were investigated. Results: Median overall survival (OS) of the whole study group was 74.9 months (42.8-107.1 months), while it was 95.2 months in resectable and 44.7 months in metastatic patients respectively (p=0.007). Epitheliolid tumor morphology was significantly associated with shortened OS as compared to other histologies (p=0.001). SMA(+) tumours were significantly correlated with low (<10/50HPF) mitotic activity (p=0.034). Moreover, SMA(+) patients tended to survive longer and had significantly longer disease-free survival (DFS) times than SMA (-) patients (37.7 months vs 15.9 months; p=0.002). High Ki-67 level (${\geq}30%$) was significantly associated with shorter OS (34 vs 95.2 months; 95%CI; p=0.001). CD34 (-) tumours were significantly associated with low proliferative tumours (Ki-67<%10) (p=0.026). Median PFS (progression-free survival) of the patients who received imatinib was 36 months (27.7-44.2 months). CD34 (-) patients had significantly longer PFS times than that of negative tumours; (50.8 vs 29.8 months; p=0.045). S100 and desmin expression did not play any role in predicting the prognosis of GISTs. Multivariate analysis demonstrated that ${\geq}10/50HPF$ mitotic activity/HPF was the only independent factor for risk of death in GIST patients. Conclusions: Despite the negative prognostic and predictive effect of high Ki-67 and CD34 expression, mitotic activity remains the strongest prognostic factor in GIST patients. SMA positivity seems to affect GIST prognosis positively. However, large-scale, multicenter studies are required to provide supportive data for these findings.

Bearing capacity of footing supported by geogrid encased stone columns on soft soil

Demir, Ahmet,Sarici, Talha Techno-Press 2017 Geomechanics & engineering Vol.12 No.3

The stone columns are increasingly being used as a soil improvement method for supporting a wide variety of structures (such as road embankment, buildings, storage tanks etc.) especially built on soft soil. Soil improvement by the stone column method overcomes the settlement problem and low stability. Nevertheless, stone column in very soft soils may not be functional due to insufficient lateral confinement. The required lateral confinement can be overcome by encasing the stone column with a suitable geosynthetic. Encasement of stone columns with geogrid is one of the ideal forms of improving the performance of stone columns. This paper presents the results of a series of experimental tests and numerical analysis to investigate the behavior of stone columns with and without geogrid encasement in soft clay deposits. A total of six small scale laboratory tests were carried out using circular footing with diameters of 0.05 m and 0.1 m. In addition, a well-known available software program called PLAXIS was used to numerical analysis, which was validated by the experimental tests. After good validation, detailed of parametric studies were performed. Different parameters such as bearing capacity of stone columns with and without geogrid encasement, stiffness of geogrid encasement, depth of encasement from ground level, diameter of stone columns, internal friction angle of crushed stone and lateral bulging of stone columns were analyzed. As a result of this study, stone column method can be used in the improvement of soft ground and clear development in the bearing capacity of the stone column occurs due to geogrid encasement. Moreover, the bearing capacity is effected from the diameter of the stone column, the angle of internal friction, rigidity of the encasement, and depth of encasement. Lateral bulging is minimized by geogrid encasement and effected from geogrid rigidity, depth of encasement and diameter of the stone column.

위생매립지에서 침출수 재순환의 효과 조사

( Ahmet Demir ),( Adem Baştürx ),( Bestamin Özkaya ),( M. Sinan Bilgili ) 한국폐기물자원순환학회 2002 APLAS Vol.2002 No.2

본 논문에서 폐기물 안정성에 미치는 침출수 재순환의 효율은 이스탄불의 유럽방향에 위치한 Odayeri 위생매립지에서 조사하였다. 이러한 목적은 매립지의 1.5 hectares(실험지 역)와 25×50×5m 부피의 두 개의 실험용 셀을 이용하였다. 수직으로 주입하는 방식은 실험지역에서 사용하였고, 표면 배수 방식은 침출수 재순환을 위한 실험용 셀에 이용하였다. 본 논문에서 얻어진 결과를 평가한다. In this study, the effect of leachate recirculation on waste stabilization was investigated at Odayeri Sanitary Landfill, which locates in the European side of Istanbul. For this purpose, 1,5 hectares (test area) of the landfill area (Odayeri), and two test cells with the dimensions of 25×50×5 m. were used. Vertical injection wells method was used at test area, and surface drainage method was used at test cells for leachate recirculation. Findings obtained from this study are evaluated.

Prognostic and Predictive Value of Hematologic Parameters in Patients with Metastatic Renal Cell Carcinoma: Second Line Sunitinib Treatment Following IFN-alpha

Dirican, Ahmet,Kucukzeybek, Yuksel,Erten, Cigdem,Somali, Isil,Demir, Lutfiye,Can, Alper,Payzin, Kadriye Bahriye,Bayoglu, Ibrahim Vedat,Akyol, Murat,Yildiz, Yasar,Koseoglu, Mehmet,Alacacioglu, Ahmet,Ta Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.3

Background: Long-term survival is a problem with locally advanced and metastatic renal cell carcinomas. Sunitinib malate is an oral multitargeted tyrosine kinase inhibitor, but data on sunitinib use as a second line treatment in metastatic renal cell carcinoma (mRCC) are limited. Prognostic and predictive value of peripheral blood markers has been shown for many cancers. Materials and Methods: Efficacy and safety profiles of sunitinib after interferon alpha (IFN-${\alpha}$) were evaluated based on retrospective data for 23 patients with mRCC. Hematological parameters (neutrophils, lymphocytes, platelets, mean platelet volume, neutrophil/lymphocyte ratio, platelet/lymphocyte ratio) were recorded at the time of metastasis. It was evaluated whether hematological parameters were prognostic and predictive factors. Results: Median progression-free survival (PFS) time was 16.5 months (95%CI: 0-34.5). Median overall survival (OS) time was 25.7 months (95%CI: 10.8-40.0). Most common side effects were neutropenia (52.2%), stomatitis (26.1%) and hand-food syndrome (26.1%). PFS was found 3.13 vs 17.1 months in patients with neutrophil / lymphocyte ratio (NLR)>3 vs $NLR{\leq}3$ (p:0.012). Median OS was 6.96 vs 27.1 months in patients with NLR>3 vs $NLR{\leq}3$ (p:0.001).While 75% of patients who responded to sunitinib had $NLR{\leq}3$, in 72% of patients with no response to sunitinib NLR>3 was detected (p:0.036). The association between the Memorial Sloan-Kettering Cancer Center (MSKCC) criteria and NLR was statistically significant (p:0.022). Conclusions: Data on second line sunitinib treatment following cytokine in mRCC are limited. In our study, we observed second line sunitinib treatment following IFN-${\alpha}$ to be effective and tolerable. NLRappeared to have prognostic and predictive value.

Treatment of Metastatic Colorectal Cancer With or Without Bevacizumab: Can the Neutrophil/Lymphocyte Ratio Predict the Efficiency of Bevacizumab?

Dirican, Ahmet,Varol, Umut,Kucukzeybek, Yuksel,Alacacioglu, Ahmet,Erten, Cigdem,Somali, Isil,Can, Alper,Demir, Lutfiye,Bayoglu, Ibrahim Vedat,Akyol, Murat,Yildiz, Yasar,Koyuncu, Betul,Coban, Eyup,Tarh Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.12

Background: The purpose of this study was to analyze the predictive value of neutrophil/lymphocyte ratio (NLR) to better clarify which patient groups will benefit the most from particular treatments like bevacizumab. Materials and Methods: A total of 245 treatment-naive metastatic colorectal cancern (mCRC) patients were retrospectively enrolled and divided into 2 groups: 145 group A patients were treated with chemotherapy in combination with bevacizumab, and 100 group B patients were treated as above without bevacizumab. Results: Group A patients had better median overall survival (OS) and progression-free survival (PFS) (24.0 and 9.0 months) than group B patients (20 and 6.0 months) (p=0.033; p=0.015). In patients with low NLR, OS and PFS were significantly longer in group A patients (27 vs 18 months, p=0.001; 11 vs 7 months, p=0.017). Conclusions: We conclude that NLR, a basal cancer related inflammation marker, is associated with the resistance to bevacizumab-based treatments in mCRC patients.

Depression, Anxiety and Sexual Satisfaction in Breast Cancer Patients and their Partners-Izmir Oncology Group Study

Alacacioglu, Ahmet,Ulger, Eda,Varol, Umut,Yildiz, Ibrahim,Salman, Tarik,Bayoglu, Vedat,Dirican, Ahmet,Demir, Lutfiye,Akyol, Murat,Yildiz, Yasar,Kucukzeybek, Yuksel,Ataman, Gorkem,Can, Huseyin,Alacacio Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.24

Background: We aimed to investigate anxiety, depression and sexual satisfaction levels and the effects of depression and anxiety upon the sexual satisfaction of Turkish breast cancer patients and their partners. Materials and Methods: Data were collected from one hundred breast cancer patients and their partners, using three forms: one covering information about socio-demographic characteristics of the patients, the Hospital Anxiety and Depression Scale (HADs) and the Golombok-Rust Inventory of Sexual Satisfaction (GRISS). Results: The frequencies, avoidance and touch subscores were statistically significantly high in the patients. Among those with high anxiety scores, the frequency, communication, satisfaction, touch, and anorgasmic subscale scores of GRISS were found to be significantly high. Among the partners whose anxiety scores were high, only the premature ejaculation subscale was statistically significant. It was determined that for partners with higher depression scores, the communication, satisfaction, avoidance, premature ejaculation and erectile dysfunction subscores of GRISS were statistically higher compared to partners with lower depression scores. Conclusions: Patients' quality of life may be increased by taking precautions to reduce their and their partners' psychosocial and psychosexual concerns.