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Zhipeng Lu,Hengbo Yin,Dezhi Gao,Aili Wang,Shuxin Liu 한국공업화학회 2015 Journal of Industrial and Engineering Chemistry Vol.31 No.-
Catalytic dehydrogenation of methanol to methyl formate over SiO2-, hydroxyapatite (HAP)-, and MgOsupportedcopper catalysts was investigated. Metallic copper (Cu0) was the active site for the methanoldehydrogenation to methyl formate. Cu/SiO2 catalyst with low basicity and weak-strength basic siteeffectively catalyzed the methanol dehydrogenation to methyl formate. Cu/HAP and Cu/MgO catalystswith high basicities and strong-strength basic sites caused the degradation of the resultant methylformate to CO and H2. Over Cu(5)/SiO2 catalyst, the reaction activation energies for methanoldehydrogenation to methyl formate and methyl formate degradation to CO and H2 were 58.3 and91.1 kJ mol 1, respectively.
Hydrogenation of ethyl acetate to ethanol over Cu/ZnO/MOx (MOx = SiO2, Al2O3, and ZrO2) catalysts
Zhipeng Lu,Hengbo Yin,Aili Wang,Jing Hu,Wuping Xue,Haixu Yin,Shuxin Liu 한국공업화학회 2016 Journal of Industrial and Engineering Chemistry Vol.37 No.-
The Cu/ZnO/SiO2, Cu/ZnO/Al2O3, and Cu/ZnO/ZrO2 catalysts prepared by the co-precipitation methodwere used for the catalytic hydrogenation of ethyl acetate to ethanol. The addition of ZnO in the Cu/ZnO/MOx catalysts improved their catalytic activities for the hydrogenation reaction. Small-sized coppercrystallite and high surface acidity favored the catalytic hydrogenation of ethyl acetate to ethanol. TheCu/ZnO/Al2O3 catalyst gave the ethanol selectivity of ca. 95% at the ethyl acetate conversion of ca. 80%when the reaction temperature was 280 8C. The reaction activation energy over Cu/ZnO/Al2O3 catalystwas 115 kJ mol 1, lower than those over the Cu/ZnO/SiO2 and Cu/ZnO/ZrO2 catalysts.
Quantitative analysis of carbon emissions in precision turning processes and industrial case study
Zhipeng Jiang,Dong Gao,Yong Lu,Linghao Kong,Zhendong Shang 한국정밀공학회 2021 International Journal of Precision Engineering and Vol.8 No.1
With growing concerns regarding the global environment, the industrial sector has played a significant role; that is, it is responsible for consuming large amount of energy and resources, while simultaneously producing wastes and carbon dioxide. A quantitative calculation of carbon emission in the turning process is presented in this paper. A generic carbon emission system boundary based on exergy balance is proposed first to avoid blurred system boundaries or the omission of elements. Then, a carbon emission model (iERWC) is formed by converting energy consumption (E), resource depletion (R) and waste generation (W) to equivalent carbon emissions (C) based on information flow (i), which effectively solves the problem of quantifying the impact of the machining process on the environment. Finally, the model is verified by experiments, and a simulation analysis is carried out. Additionally, the influence rule of processing parameters on carbon emissions is analyzed, and the cutting parameter that produces the lowest carbon emission is given.
MiR-200c-3p aggravates gastric cell carcinoma via KLF6
Wang Ying,Lu Kaijuan,Li Weibing,Wang Zhigang,Ding Jing,Zhu Zeyu,Li Zhipeng 한국유전학회 2021 Genes & Genomics Vol.43 No.11
Background Gastric cell carcinoma (GCC) is a common and high-incidence malignant gastrointestinal cancer that seriously threatens human life and safety. Evidences suggest that microRNAs (miRNAs) exhibit an essential role in regulating the occurrence and development of GCC, while the efects and possible mechanisms remain to be further explored. Objective This study was designed to explore whether miR-200c-3p exerted its functional role in the growth and metastasis of GCC, and investigate the possible mechanisms. Methods The expression levels of miR-200c-3p in GCC tissues and cell lines were detected by qRT-PCR analysis. The functional role of miR-200c-3p in the viability, proliferation, migration and invasion of GCC cells were evaluated by CCK-8, EdU, wound healing and Transwell assays. In addition, the candidate targets of miR-200c-3p was predicted and confrmed by dual-luciferase reporter assay. Moreover, the relationship between miR-200c-3p and target (Krüppel like factor 6, KLF6) was assessed by qRT-PCR and western blot assays. Besides, the expression levels of KLF6 in GCC cells were determined by qRT-PCR and western blot assays. Furthermore, the role of KLF6 in the viability, proliferation, migration and invasion of GCC cells mediated with miR-200c-3p mimics was evaluated by CCK-8, EdU, wound healing and Transwell assays. Results In the present study, a new tumor promoting function of miR-200c-3p was disclosed in GCC. We found that the expression of miR-200c-3p was obviously increased in clinic GCC tissues and cell lines. In addition, down-regulation of miR-200c-3p suppressed cell viability, proliferation, migration, and invasion in GCC cells. Moreover, KLF6 was verifed as a direct target of miR-200c-3p by binding its 3’-UTR. Additionally, KLF6 was remarkably decreased and was negatively associated with the miR-200c-3p expression in GCC cell lines. Furthermore, over-expression of KLF6 retarded the efects of miR-200c-3p on the growth and metastasis of GCC cell lines. Conclusions MiR-200c-3p potentially played a tumor-promoting role in the occurrence and development of GCC, which may be achieved by targeting KLF6.
A Source Code Cross-site Scripting Vulnerability Detection Method
Mu Chen,Lu Chen,Zhipeng Shao,Zaojian Dai,Nige Li,Xingjie Huang,Qian Dang,Xinjian Zhao 한국인터넷정보학회 2023 KSII Transactions on Internet and Information Syst Vol.17 No.6
To deal with the potential XSS vulnerabilities in the source code of the power communication network, an XSS vulnerability detection method combining the static analysis method with the dynamic testing method is proposed. The static analysis method aims to analyze the structure and content of the source code. We construct a set of feature expressions to match malignant content and set a "variable conversion" method to analyze the data flow of the code that implements interactive functions. The static analysis method explores the vulnerabilities existing in the source code structure and code content. Dynamic testing aims to simulate network attacks to reflect whether there are vulnerabilities in web pages. We construct many attack vectors and implemented the test in the Selenium tool. Due to the combination of the two analysis methods, XSS vulnerability discovery research could be conducted from two aspects: “white-box testing” and “black-box testing”. Tests show that this method can effectively detect XSS vulnerabilities in the source code of the power communication network.
Jing Hua,Zhipeng Lu,Hengbo Yin,Wuping Xue,Aili Wang,Lingqin Shen,Shuxin Liu 한국공업화학회 2016 Journal of Industrial and Engineering Chemistry Vol.40 No.-
Aldol condensation of acetic acid with formaldehyde to acrylic acid was catalyzed by the SiO2-, SBA-15-,and HZSM-5-supported vanadium phosphorous oxide (V-P-O) catalysts prepared by the incipientwetness impregnation. The supports obviously increased the surface areas and changed the acid–baseproperties of the as-prepared catalysts. V-P-O/SBA-15 catalysts with high acid and alkali quantitiesexhibited high catalytic activities for the aldol condensation of acetic acid with formaldehyde to acrylicacid. When the V-P-O/SBA-15 catalyst with the P/V mole ratio of 2.0:1 catalyzed the reaction at 330–370 8C, the acrylic acid selectivities were 90.8–70.2% at the formaldehyde conversions of 14.3–68.7%.
Siqi Li,Zhipeng Su,Chengjun Zhang,Zhuofei Xu,Xiaoping Chang,Jiawen Zhu,Ran Xiao,Lu Li,Rui Zhou 한국유전학회 2018 Genes & Genomics Vol.40 No.8
Porcine pleuropneumonia caused by Actinobacillus pleuropneumoniae has led to severe economic losses in the pig industry worldwide. A. pleuropneumoniae displays various levels of antimicrobial resistance, leading to the dire need to identify new drug targets. Protein–protein interaction (PPI) network can aid the identification of drug targets by discovering essential proteins during the life of bacteria. The aim of this study is to identify drug target candidates of A. pleuropneumoniae from essential proteins in PPI network. The homologous protein mapping method (HPM) was utilized to construct A. pleuropneumoniae PPI network. Afterwards, the subnetwork centered with H-NS was selected to verify the PPI network using bacterial two-hybrid assays. Drug target candidates were identified from the hub proteins by analyzing the topology of the network using interaction degree and homologous comparison with the pig proteome. An A. pleuropneumoniae PPI network containing 2737 non-redundant interaction pairs among 533 proteins was constructed. These proteins were distributed in 21 COG functional categories and 28 KEGG metabolic pathways. The A. pleuropneumoniae PPI network was scale free and the similar topological tendencies were found when compared with other bacteria PPI network. Furthermore, 56.3% of the H-NS subnetwork interactions were validated. 57 highly connected proteins (hub proteins) were identified from the A. pleuropneumoniae PPI network. Finally, 9 potential drug targets were identified from the hub proteins, with no homologs in swine. This study provides drug target candidates, which are promising for further investigations to explore lead compounds against A. pleuropneumoniae.
A Novel PCCM Voltage-Fed Single-Stage Power Factor Correction Full-Bridge Battery Charger
Zhang, Taizhi,Lu, Zhipeng,Qian, Qinsong,Sun, Weifeng,Lu, Shengli The Korean Institute of Power Electronics 2016 JOURNAL OF POWER ELECTRONICS Vol.16 No.3
A novel pseudo-continuous conduction mode (PCCM) voltage-fed single-stage power factor correction (PFC) full-bridge battery charger is proposed in this paper. By connecting a freewheeling transistor in parallel with an input inductor, the PFC cell can operate in the PCCM with a constant duty ratio. Thus, the dc/dc stage can be designed using this constant duty ratio and the restriction on the duty ratio of the PFC cell is eliminated. As a result, the input current distortion is less and the dc bus voltage becomes controllable over the wide output power range of the battery charger. Moreover, the operation principle of the dc/dc stage is designed to be similar to that of a conventional phase-shifted full-bridge converter. Therefore, it is easy to implement. In this paper, the operation of the new converter is explained, and the design considerations of the controller and key parameters are presented. Simulation and experimental results obtained from a 1 kW prototype are given to confirm the operation of the proposed converter.
A Novel PCCM Voltage-Fed Single-Stage Power Factor Correction Full-Bridge Battery Charger
Taizhi Zhang,Zhipeng Lu,Qinsong Qian,Weifeng Sun,Shengli Lu 전력전자학회 2016 JOURNAL OF POWER ELECTRONICS Vol.16 No.3
A novel pseudo-continuous conduction mode (PCCM) voltage-fed single-stage power factor correction (PFC) full-bridge battery charger is proposed in this paper. By connecting a freewheeling transistor in parallel with an input inductor, the PFC cell can operate in the PCCM with a constant duty ratio. Thus, the dc/dc stage can be designed using this constant duty ratio and the restriction on the duty ratio of the PFC cell is eliminated. As a result, the input current distortion is less and the dc bus voltage becomes controllable over the wide output power range of the battery charger. Moreover, the operation principle of the dc/dc stage is designed to be similar to that of a conventional phase-shifted full-bridge converter. Therefore, it is easy to implement. In this paper, the operation of the new converter is explained, and the design considerations of the controller and key parameters are presented. Simulation and experimental results obtained from a 1 kW prototype are given to confirm the operation of the proposed converter.