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- 저자 : Zhenqing Wang (검색결과 3 건)
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Shuifan Zhou,Zhenqing Hou,Yang Li,Fei Cui,Mengmeng Jia,Xiangrui Yang,Yange Wang,Liya Xie,Qiqing Zhang 한국고분자학회 2014 Macromolecular Research Vol.22 No.1
The efficacy of magnetic nanoparticles (MNPs) for biomedical applications depends on the specic targetingcapacity, blood circulation time and magnetic susceptibility. Functionalized chitosan-coated Fe3O4 nanoparticles(CS-coated Fe3O4 NPs) were synthesized by a non-solvent-aided coacervation procedure followed by a chemicalcrosslinking procedure. The surfaces of CS-coated Fe3O4 NPs were successfully functionalized with folate-poly(ethyleneglycol)-COOH (FA-PEG) to obtain novel FA-PEG-CS-coated Fe3O4 NPs endowed with long blood circulationand specic targeting capacity. The as-synthesized NPs were characterized by dynamic light scattering, transmissionelectron microscope, X-ray diffraction, thermal gravimetric analysis, vibration sample magnetometer, Fourier transforminfrared spectroscopy, and confocal laser scanning microscopy. As a result, the novel FA-PEG-CS-coated Fe3O4 NPsshowed excellent biocompatibility, magnetic properties, good dispersibility, and proper hydrodynamic sizes in an aqueousmedium. The specific targeting capacity of the as-synthesized NPs to cancer cells was also investigated. It wasobserved that the uptake of the FA-PEG-CS-coated Fe3O4 NPs by HeLa cells was significantly enhanced comparedto the CS-coated Fe3O4 NPs and mPEG-CS-coated Fe3O4 NPs. These results clearly indicate that our novel FA-PEGCS-coated Fe3O4 NPs with remarkable specific targeting capacity, long blood circulation, and superparamagnetismhold great promise for biomedical applications, including targeted drug delivery and hyperthermia therapy.
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Complex Modification of Hypereutectic Al-Si Alloy by a New Al-Y-P Master Alloy
Min Zuo,Degang Zhao,Zhenqing Wang,Haoran Geng 대한금속·재료학회 2015 METALS AND MATERIALS International Vol.21 No.4
In this article, a novel Al-6Y-2P master alloy with cubic YP particles was successfully synthesized and its complex modification performance on Al-18Si alloy has also been investigated. With the doping of La and Ce, (YxLa1-x)P and (YxCe1-x)P particles still exhibit cubic morphologies in three dimensional spaces (3-D space). The excellent complex modification of Al-18Si alloy can be obtained with the addition of Al-6Y-2P master alloy. Under the optimized conditions, i.e. melting temperature of 780 °C, addition level of 1.5 wt% and holding time of 30-60 min, the tensile strength and Brinell hardness of Al-18Si alloys can be significantly increased by 16.8% and 17.1%, respectively. It is proposed that the Si atoms in the melt could promote the structure evolution of YP to AlP with the release of Y, which would be reason for the excellent composite modification performance of the developed Al-6Y-2P master alloy.
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Stability Analysis of Prefabricated Underground Granary Composite Silo Walls
Hao Zhang,Xinkang Wang,Lei Chen,Jun Chuai,Zhenqing Wang 대한토목학회 2023 KSCE Journal of Civil Engineering Vol.27 No.11
The prefabricated steel plate-concrete composite silos have been recently used for underground granaries. As the buried depth and diameter-thickness ratio of underground silos increase, the calculation of elastic stability, which takes into account the effects of prefabricated joints, becomes a primary consideration in the design of the silo walls. In the present study, the equation to estimate the elastic critical pressure of double-layer heterogeneous cast-in-situ silos under uniform external pressure was proposed first. The theoretical solutions were then compared with the numerical results and the accuracy of the equation was verified. To derive the critical pressure of prefabricated steel plate-concrete silo walls, an equivalent joint design method was proposed and verified by a series of numerical analyses for different models. The results indicate that if the bending stiffness ratio of the joint is larger than the bending stiffness of the composite silo wall section, the prefabricated double-layer composite silo walls are equivalent to cast-in-situ double-layer composite silo walls, and the equation to evaluate the elastic critical pressure of double-layer heterogeneous cast-in-situ silo walls under uniform external pressure could be used to derive the critical pressure of prefabricated steel plate-concrete silo walls. The bending tests of the full-scale steel plate-concrete composite silo wall models with and without joints were conducted and the experimental results indicate that the assumption of a rigid connection between the steel plate and concrete was reasonable, and the equivalence of prefabricated composite silos to cast-in-situ composite silos to obtain the elastic critical pressure is feasible and the result is reliable.
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