중국 하남성 고등학생이 지각한 체육 학습환경과 수업만족의 관계

장정정(Zhang Jingting),김영훈(Kim, Young-Hoon),이병찬(Lee, Byung-Chan) 한국체육과학회 2020 한국체육과학회지 Vol.29 No.2

The purpose of the study is to find out relationship between P.E. course learning environment and Class satisfaction of high school students in Henan province, China. In order to achieve the goal, conducted random sampling to select the high school, and used convenience sampling to distribute the questionnaires. total of 1,400 questionnaires used for analysis. Based on the collected data, Win SAS Ver.9.2 was applied for analysis with frequency analysis, confirmatory analysis, construct validity, correlation analysis and multiple linear regression analysis. The results of this study can be summarized as follows: First, sub-variables of learning environment, perceived challenge, perceived risk, perceived competition and perceived control, have positive influence on mastery experience. sub-variables of class satisfaction; cognitive development had positive relationship with perceived challenge, perceived risk, perceived competition, and normative success had positive relation to perceived challenge, perceived risks, perceived competition. Interaction with others positively influenced on perceived risk and perceived competition. Health and enjoyment factor had significant influence on perceived risks, perceived competition and perceived control. And enjoyment and relaxation significantly influenced on perceived risks, perceived competition and perceived control.

TGF-β promotes pericyte-myofibroblast transition in subretinal fibrosis through the Smad2/3 and Akt/mTOR pathways

Zhao Zhenzhen,Zhang Yumeng,Zhang Chaoyang,Zhang Jingting,Luo Xueting,Qiu Qinghua,Luo Dawei,Zhang Jingfa 생화학분자생물학회 2022 Experimental and molecular medicine Vol.54 No.-

Subretinal fibrosis remains a major obstacle to the management of neovascular age-related macular degeneration. Choroidal pericytes were found to be a significant source of subretinal fibrosis, but the underlying mechanisms of pericyte-myofibroblast transition (PMT) remain largely unknown. The goal of this study was to explore the role and potential mechanisms by which PMT contributes to subretinal fibrosis. Choroidal neovascularization (CNV) was induced by laser photocoagulation in transgenic mice with the collagen1α1-green fluorescent protein (Col1α1-GFP) reporter, and recombinant adeno-associated virus 2 (rAAV2)-mediated TGF-β2 (rAAV2-TGF-β2) was administered intravitreally to further induce PMT. Primary mouse choroidal GFP-positive pericytes were treated with TGF-β2 in combination with siRNAs targeting Smad2/3, the Akt inhibitor MK2206 or the mTOR inhibitor rapamycin to examine cell proliferation, migration, and differentiation into myofibroblasts. The involvement of the Akt/mTOR pathway in PMT in subretinal fibrosis was further investigated in vivo. Intraocular TGF-β2 overexpression induced GFP-positive pericyte infiltration and PMT in subretinal fibrosis, which was mimicked in vitro. Knockdown of Smad2/3 or inhibition of Akt/mTOR decreased cell proliferation, PMT and migration in primary mouse pericytes. Combined inhibition of Smad2/3 and mTOR showed synergistic effects on attenuating α-smooth muscle actin (α-SMA) expression and cell proliferation. In mice with laser-induced CNV, the administration of the Akt/mTOR inhibitors suppressed pericyte proliferation and alleviated the severity of subretinal fibrosis. Our results showed that PMT plays a pivotal role in subretinal fibrosis, which was induced by TGF-β2 through the Smad2/3 and Akt/mTOR pathways. Thus, inhibiting PMT may be a novel strategy for the treatment of subretinal fibrosis.

Private Blockchain-Based Secure Access Control for Smart Home Systems

( Jingting Xue ),( Chunxiang Xu ),( Yuan Zhang ) 한국인터넷정보학회 2018 KSII Transactions on Internet and Information Syst Vol.12 No.12

Smart home systems provide a safe, comfortable, and convenient living environment for users, whereby users enjoy featured home services supported by the data collected and generated by smart devices in smart home systems. However, existing smart devices lack sufficient protection in terms of data security and privacy, and challenging security and privacy issues inevitably emerge when using these data. This article aims to address these challenging issues by proposing a private blockchain-based access control (PBAC) scheme. PBAC involves employing a private blockchain to provide an unforgeable and auditable foundation for smart home systems, that can thwart illegal data access, and ensure the accuracy, integrity, and timeliness of access records. A detailed security analysis shows that PBAC could preserve data security against various attacks. In addition, we conduct a comprehensive performance evaluation to demonstrate that PBAC is feasible and efficient.

Multimodal prerehabilitation for elderly patients with sarcopenia in colorectal surgery

Wu Jingting,Chi Hannah,Kok Shawn,Chua Jason M.W.,Huang Xi-Xiao,Zhang Shipin,Mah Shimin,Foo Li-Xin,Peh Hui-Yee,Lee Hui-Bing,Tay Phoebe,Tong Cherie,Ladlad Jasmine,Tan Cheryl H.M.,Khoo Nathanelle,Aw Dari 대한대장항문학회 2024 Annals of Coloproctolgy Vol.40 No.1

Sarcopenia, which is characterized by progressive and generalized loss of skeletal muscle mass and strength, has been well described to be associated with numerous poor postoperative outcomes, such as increased perioperative mortality, postoperative sepsis, prolonged length of stay, increased cost of care, decreased functional outcome, and poorer oncological outcomes in cancer surgery. Multimodal prehabilitation, as a concept that involves boosting and optimizing the preoperative condition of a patient prior to the upcoming stressors of a surgical procedure, has the purported benefits of reversing the effects of sarcopenia, shortening hospitalization, improving the rate of return to bowel activity, reducing the costs of hospitalization, and improving quality of life. This review aims to present the current literature surrounding the concept of sarcopenia, its implications pertaining to colorectal cancer and surgery, a summary of studied multimodal prehabilitation interventions, and potential future advances in the management of sarcopenia.

Monitoring conservation effects on a Chinese indigenous chicken breed using major histocompatibility complex B-G gene and DNA Barcodes

Tu, Yunjie,Shu, Jingting,Ji, Gaige,Zhang, Ming,Zou, Jianmin Asian Australasian Association of Animal Productio 2018 Animal Bioscience Vol.31 No.10

Objective: We report monitoring conservation effect for a Chinese indigenous chicken (Langshan) breed using major histocompatibility complex (MHC) and DNA barcords. Methods: The full length of MHC B-G gene and mitochondrial cytochrome oxidase I (COI) gene in generations 0, 5, 10, 15, 16, and 17 was measured using re-sequencing and sequencing procedures, respectively. Results: There were 292 single nucleotide polymorphisms of MHC B-G gene identified in six generations. Heterozygosity (He) and polymorphic information content (PIC) of MHC B-G gene in generations 10, 15, 16, and 17 remained stable. He and PIC of MHC B-G gene were different in six generations, with G10, G15, G16, G17 >G5>G0 (p<0.05). For the COI gene, there were five haplotypes in generations 0, 5, 10, 15, 16, and 17. Where Hap2 and Hap4 were the shared haplotypes, 164 individuals shared Hap2 haplotypes, while Hap1 and Hap3 were the shared haplotypes in generations 0 and 5 and Hap5 was a shared haplotype in generations 10, 15, 16, and 17. The sequence of COI gene in 6 generations was tested by Tajima's and D value, and the results were not significant, which were consistent with neutral mutation. There were no differences in generations 10, 15, 16, and 17for measured phenotypic traits. In other generations, for annual egg production, with G5, G10, G15, G16, G17>G0 (p<0.05). For age at the first egg and age at sexual maturity, with G10, G15, G16, G17>G5>G0 (p<0.05). Conclusion: Combined with the results of COI gene DNA barcodes, MHC B-G gene, and phenotypic traits we can see that genetic diversity remained stable from generations 10 to 17 and the equimultiple random matching pedigrees conservation population conservation effect of Langshan chicken was effective as measured by these criteria.