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Zhang Jian Hao,Li Hai Hai,Zhang Gui Jie,Zhang Ying Hui,Liu Bo,Huang Shuai,Guyader Jessie,Zhong Rong Zhen 아세아·태평양축산학회 2022 Animal Bioscience Vol.35 No.10
Objective: Tan lambs (n = 36, 3 mo old, 19.1±0.53 kg) were used to assess effects of dietary guanidinoacetic acid (GAA) and rumen-protected methionine (RPM) on growth performance, carcass traits, meat quality, and serum parameters. Methods: Lambs were randomly assigned to three treatment groups, with 6 pens per group and 2 lambs per pen. Dietary treatments were: basal diet alone (I); basal diet supplemented with 0.08% GAA+0.06% RPM (II); and basal diet supplemented with 0.08% GAA+0.08% RPM (III). Diets were provided three times a day for 90 d. Intake per pen was recorded daily and individual lamb body weight (BW) was measured monthly. Carcass traits were measured after slaughter and meat quality at the end of the experiment, blood samples were taken on a subgroup of lambs for analysis of indicators mostly related to protein metabolism. Results: Final BW and average daily gain for the first and second month, and for the entire experiment were greater in Treatment II compared to Treatment I (p<0.05), whereas feed to gain ratio was lower (p<0.05). Treatment II had the optimal dressing percentage and net meat weight proportion, as well as crude protein and intramuscular fat concentrations in muscles. Treatment II improved meat quality, as indicated by the greater water holding capacity, pH after 45 min and 48 h, and lower shear force and cooking loss. Dietary supplementation of GAA and RPM also increased the meat color a* and b* values at 24 h. Finally, Treatment II increased total protein, and serum concentrations of albumin and creatinine, but decreased serum urea nitrogen concentrations, indicating improved protein efficiency. Conclusion: In this study, 0.08% GAA+0.06% RPM supplementation improved growth performance and meat quality of Tan lambs. Objective: Tan lambs (n = 36, 3 mo old, 19.1±0.53 kg) were used to assess effects of dietary guanidinoacetic acid (GAA) and rumen-protected methionine (RPM) on growth performance, carcass traits, meat quality, and serum parameters.Methods: Lambs were randomly assigned to three treatment groups, with 6 pens per group and 2 lambs per pen. Dietary treatments were: basal diet alone (I); basal diet supplemented with 0.08% GAA+0.06% RPM (II); and basal diet supplemented with 0.08% GAA+0.08% RPM (III). Diets were provided three times a day for 90 d. Intake per pen was recorded daily and individual lamb body weight (BW) was measured monthly. Carcass traits were measured after slaughter and meat quality at the end of the experiment, blood samples were taken on a subgroup of lambs for analysis of indicators mostly related to protein metabolism.Results: Final BW and average daily gain for the first and second month, and for the entire experiment were greater in Treatment II compared to Treatment I (p<0.05), whereas feed to gain ratio was lower (p<0.05). Treatment II had the optimal dressing percentage and net meat weight proportion, as well as crude protein and intramuscular fat concentrations in muscles. Treatment II improved meat quality, as indicated by the greater water holding capacity, pH after 45 min and 48 h, and lower shear force and cooking loss. Dietary supplementation of GAA and RPM also increased the meat color a* and b* values at 24 h. Finally, Treatment II increased total protein, and serum concentrations of albumin and creatinine, but decreased serum urea nitrogen concentrations, indicating improved protein efficiency.Conclusion: In this study, 0.08% GAA+0.06% RPM supplementation improved growth performance and meat quality of Tan lambs.
Implementation and Application of Guidance law using Aerodynamic Data for Simulation Purposes
Zhang Wei,Jin Jian-yun,Khayyam Masood,Li Lin,Ma Ze-hao 제어로봇시스템학회 2014 제어로봇시스템학회 국제학술대회 논문집 Vol.2014 No.10
This paper describes a new technique for simulating the guidance of a SAM (surface to air missile) without the help of a controller. This analysis is fully automated in a closed loop using the features of commercial software MATLAB. The guidance algorithm is simulated with the help of aerodynamic data. Control law is not used for obtaining the desired deflections of the control surfaces rather reverse aerodynamics are used to calculate the commanded accelerations which are implied by the guidance system. The addition required in aerodynamics coefficients are calculated through reverse aerodynamics which are later on used to calculate the deflections required. These deflections are passed through actuator dynamics to obtain real deflections. The deflections obtained from actuator are then passed to aerodynamic block to calculate the desired aerodynamic forces. The forces update the current information and LOS (line of sight) of the guidance block thus creating a closed loop system. This technique has a unique solution for a unique guidance algorithm thus ensuring the path followed by the SAM is only dependent on guidance algorithm. This enables an efficient way to diagnose which guidance algorithm is suitable for a particular system without getting into the complexity of updating the controller and re-tuning of controller gains.
Hao Cao,Jian Gang Yang,Wan Fu Zhang,Rui Guo 대한기계학회 2013 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.27 No.7
This study presents an improved impedance method based on unbalanced synchronous excitation to identify the rotordynamic coefficients of labyrinth seals. The rotordynamic coefficient test is implemented near the cylinder resonance frequency to enlarge the influence of seal force. The force generated by the rotor unbalance is used to provide synchronous frequency excitation for the rotordynamic coefficient test. Four unique equations are set up under two sets of different rotor unbalance conditions to obtain four unknown complex rotordynamic coefficients. The factors that influence the rotordynamic coefficients of seals, namely, unbalance mass, inlet/outlet pressure ratio, and rotating speed, are considered. The dynamic coefficients are minimally affected by different rotor unbalances. The direct items are nearly equal with same signs, whereas the cross-coupled items are nearly equal with opposite signs. All coefficients increase with increasing inlet/outlet pressure ratio and rotating speed. The direct stiffness coefficients increase more quickly than the cross-coupled items. In addition, the effect stiffness and effect damping coefficients are analyzed; results indicate that both coefficients increase with increasing rotating speed.
Hao Wang,Zhi-Jing Ni,Wen-Ping Ma,Chang-Bing Song,Jian-Guo Zhang,Kiran Thakur,Zhao-Jun Wei 한국식품과학회 2019 Food Science and Biotechnology Vol.28 No.2
In this study, we evaluated the effect of additionof non-volatile compounds (sodium sulfite, tartaric acid,tannin, and glucose) on the rheological properties, releaseof aroma compounds, and color of the red wine. Whiledetermining the rheological properties of the supplementedsamples, non-Newtonian fluidic and shear-thinningbehavior of samples was noticed. The viscosity of thesesamples was found in negative correlation with the dose ofaddition of various non-volatile substances. The aromaprofile of red wine after additions showed the change in therelease of the nine key aroma compounds. Among themethyl hexanoate, phenylethyl alcohol, octanoic acid, diethylsuccinate, and ethyl octanoate were profoundly increased. Further, the color of red wines was improved in the presenceof tartaric acid and tannin. Overall, supplementationof various substances during storage period of three differentwines could enormously affect the sensory characteristicsin a dose dependent manner.
New Therapeutic Schedule for Prostatic Cancer-3 Cells with ET-1 RNAi and Endostar
Zhang, Hao-Jie,Qian, Wei-Qing,Chen, Ran,Sun, Zhong-Quan,Song, Jian-Da,Sheng, Lu Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.23
Background: Endothelin-1 and Endostar are both significant for the progression, proliferation, metastasis and invasion of cancer. In this paper, we studied the effect of ET-1 RNAi and Endostar in PC-3 prostatic cancer cells. Materials and Methods: The lentiviral vector was used in the establishment of ET-1 knockdown PC-3 cells. Progression and apoptosis were assessed by CKK-8 and flow cytometry, respectively. Transwell assay was used to estimate invasion and signaling pathways were studied by Western blotting. Results: ET-1 mRNA and protein in ET-1 knockdown PC-3 cells were reduced to 26.4% and 22.4% compared with control group, respectively. ET-1 RNAi and Endostar both were effective for the suppression of progression and invasion of PC-3 cells. From Western blotting results, the effects of ET-1 regulation and Endostar on PC-3 cells were at least related to some signaling pathways involving PI3K/Akt/Caspase-3, Erk1/2/Bcl-2/Caspase-3 and MMPs (MMP-2 and MMP-9). Furthermore, combined treatment of ET-1RNAi and Endostar was found to be more effective than single treatment. Conclusions: Both ET-1 RNAi and Endostar can inhibit the progression and invasion of PC-3 cells, but combined treatment might be a better therapeutic schedule.
Zhang Xiao-wen,Li Jing,Hou Wen-Bin,Jiang Yue,Zheng Ruo-Xiang,Xu De-hao,Shen Chen,Robinson Nicola,Liu Jian-Ping 한국한의학연구원 2023 Integrative Medicine Research Vol.12 No.1
Background: To explore the effectiveness and safety of Chinese herbal medicine (CHM) for drug-induced liver injury (DILI) in patients with human immunodeficiency virus (HIV)/acquired immunodeficiency syn- drome (AIDS). Methods: A systematic search was made of eight databases (Pubmed, Cochrane Library, Web of Science, Embase, CNKI, Wanfang, VIP, Sinomed) and two trial registries (WHO ICTRP, ClinicalTrials.gov) from in- ception to September 2022. The effect size was presented as risk ratio (RR) or mean difference (MD) with their 95% confidence interval (CI). The Cochrane Risk of Bias and Grading of Recommendations, Assess- ment, Development and Evaluations (GRADE) tools were used for quality appraisal. Results: Ten randomized controlled trials (RCTs) involving 732 participants were included. Comparing CHM alone with routine treatment, the CHM group showed lower aspartate aminotransferase (MD = -11.47 U/L, 95%CI[-13.05, -9.89], low certainty), lower alanine aminotransferase (MD = -2.68 U/L, 95%CI[-4.27, - 1.08], low certainty), lower total bilirubin (MD = -4.31 mmol/L, 95%CI[-5.66, -2.96], low certainty), lower bilirubin direct (MD = -3.19 mmol/L, 95%CI[-3.87, -2.51], low certainty), and higher effective rate (assessed by symptoms and liver indicators) (RR = 1.13, 95%CI[1.06, 1.20], low certainty). A significant difference was also found in CHM plus routine treatment versus routine treatment in the previous outcomes. No signif- icant difference was found on helper T cells among these comparisons. Only one RCT reported safety of CHM and found no adverse reaction during the trial. Conclusions: CHM may improve the liver function indices and effective rate for HIV/AIDS patients with DILI. However, the sample size was small and quality was low. Larger-samples of high-quality trials are needed.
Reliability analysis of nuclear safety-class DCS based on T-S fuzzy fault tree and Bayesian network
Zhang Xu,Deng Zhiguang,Jian Yifan,Huang Qichang,Peng Hao,Ma Quan 한국원자력학회 2023 Nuclear Engineering and Technology Vol.55 No.5
The safety-class (1E) digital control system (DCS) of nuclear power plant characterized structural multiple redundancies, therefore, it is important to quantitatively evaluate the reliability of DCS in different degree of backup loss. In this paper, a reliability evaluation model based on T-S fuzzy fault tree (FT) is proposed for 1E DCS of nuclear power plant, in which the connection relationship between components is described by T-S fuzzy gates. Specifically, an output rejection control system is chosen as an example, based on the T-S fuzzy FT model, the key indicators such as probabilistic importance are calculated, and for a further discussion, the T-S fuzzy FT model is transformed into Bayesian Network(BN) equivalently, and the fault diagnosis based on probabilistic analysis is accomplished. Combined with the analysis of actual objects, the effectiveness of proposed method is proved
Immersion and Invariance Adaptive Control for a Class of Nonlinear Systems With Uncertain Parameters
Jian-Hui Wang,Guang-Ping He,Gui-Bin Bian,Jun-Jie Yuan,Shi-Xiong Geng,Cheng-Jie Zhang,Cheng-Hao Zhao 제어·로봇·시스템학회 2024 International Journal of Control, Automation, and Vol.22 No.9
An adaptive control method based on immersion and invariance (I&I) is presented in a class of nonlinear systems with time-varying uncertain parameters. A parameter estimation law based on reference models using I&I is designed to accelerate the convergence of estimated parameters to the true value, enabling the closed-loop system to reach the predefined target system on the manifold more quickly and reducing the energy consumption of the system. The inherent integrability obstacles in I&I are overcome by using dynamic scaling techniques, reducing the complexity of controller design. Stability analysis of the closed-loop system demonstrates that the proposed control method can achieve asymptotic stability control of the target system, and verified the robustness of the closedloop system in the face of external disturbances. Finally, simulations of attitude tracking control demonstrate the effectiveness and superiority of the proposed method.