http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Zakaria El Gataa,Samira El Hanafi,Fadil Basheer,Zakaria Kehel,Yassin bouhouch,Khalil El Messoadi,Kenza Eddakir,Nawel Ladraa,Karima Samir,Wuletaw Tadesse 한국작물학회 2021 Journal of crop science and biotechnology Vol.24 No.4
Abiotic stress, especially drought and heat, afects cereal yields and wheat production worldwide, more particularly in West and South Asia, North Africa, and sub-Saharan Africa. The present study was carried out on 229 spring bread wheat (Triticum aestivum L.) genotypes from the International Center for Agricultural Research in Dry Areas (ICARDA) to identify the genomic region and marker-trait associations (MTA) responsible for drought and heat tolerance. The study was carried out in three diferent locations, Merchouch station (Morocco), Sids station (Egypt), and Wadmadani station (Sudan) over a period of 2 years (2018 and 2019). A genome-wide association study (GWAS) was performed using the mixed linear model (MLM) and 13,698 DArTseq markers were used for genotyping. Linkage disequilibrium revealed that 1914 pairs of markers mapped on the B sub- genome, followed by D and A sub-genomes with 1745 and 1726 paired markers, respectively. A total of 342 MTAs (P<0.05) and 78 genes were identifed in the three environments, of which 134 MTAs were recorded at Sids station and 128 and 80 MTAs at Wadmadani station and Merchouch station. The markers 822,842, 196,565 and 753,901 were signifcantly correlated with grain yield under drought, heat and yield potential stations Morocco, Sudan, and Egypt, respectively. The markers and candidate genes identifed in this study have potentials for marker-assisted selection to develop high yielding wheat genotypes with resistance to heat and drought stresses.
Zakaria Zainul Amiruddin,Neelendran M,Pubalan S,Sulaiman MR,Fatimah CA Kyung Hee Oriental Medicine Research Center 2006 Oriental pharmacy and experimental medicine Vol.6 No.3
The present study was carried out to determine the involvement of opioid and non-opioid receptor and the effect of pH and enzymes on the recently reported antinociceptive activity of aqueous extract of Corchorus olitorius (AECO) leaves using the abdominal constriction test. The extract was prepared by soaking the dried powdered leaves of Corchorus (C.) olitorius in distilled water overnight, and the supernatant obtained was considered as a stock solution with 100% concentration/ strength. The extract, administered subcutaneously in the concentrations/ strength of 10, 50 and 100%, was found to show a significant concentration-independent antinociception. The 50% concentration AECO were further used to study on the above mentioned parameters. The extract exhibited: significant (P < 0.05) decreased in activity when pre-treated (s.c.) against 10 mg/kg naloxonazine, bicuculine (10 mg/kg), phenoxybenzamine (10 mg/kg), 10 mg/kg pindolol, and 5 mg/kg mecamylamme, but not 10 mg/kg naltrindole, 10 mg/kg atropine, respectively; significant (P < 0.05) decreased in activity after pre-treatment against 10% a-amylase, but not 1 % protease or 10% lipase and; significant (P < 0.05) decreased in activity after exposure to alkaline condition (pH between 9 and 13) while maintaining the activity at acidic condition, respectively. The C. olitorius leaves antinociception, which involved, at least in part, activation of $\mu-opioid,\;\alpha-and\;\beta-adrenergic$, and nicotinic receptors, was found to decrease under alkaline condition and in the presence of $\alpha-amylase$.
Zakaria, M. 한국산업정보응용수학회 2002 한국산업정보응용수학회 Vol.6 No.2
The influence of unsteady boundary layer magnetohydrodynamic flow with thermal relaxation of perfectly conducting fluid, past a semi-infinite plate, is considered. The governing non linear partial differential equations are solved wing the method of successive approximations. This method is used to obtain the solution for the unsteady boundary layer magnetohydrodynamic flow in the special form when the free stream velocity exponentially depends on time. The effects of Alfven velocity α on the velocity is discussed, and illustrated graphically for the problem.
Zakaria, Azza S.,Edward, Eva A.,Mohamed, Nelly M. The Korean Society for Microbiology and Biotechnol 2019 한국미생물·생명공학회지 Vol.47 No.4
Targeting the pathogen viability using drugs is associated with development of drug resistance due to selective pressure. Hence, there is an increased interest in developing agents that target bacterial virulence. In this study, the inhibitory effect of ciclopirox, an antifungal agent with iron chelation potential, on the microbial virulence factors was evaluated in 26 clinical MDR Pseudomonas aeruginosa isolates collected from Alexandria Main University Hospital, a tertiary hospital in Egypt. Treatment with 9 ㎍/ml ciclopirox inhibited the hemolytic activity in 70% isolates, reduced pyocyanin production, decreased protease secretion in 46% isolates, lowered twitching and swarming motility, and decreased biofilm formation by 1.5- to 4.5-fold. The quantitative real-time PCR analysis revealed that treatment with ciclopirox downregulated the expression levels of alkaline protease (aprA) and pyocyanin (phzA1). Ciclopirox is used to treat hematological malignancies and the systemic administration of ciclopirox is reported to have adequate oral absorption with a satisfactory drug safety profile. It is important to calculate the appropriate clinical dose and therapeutic index to reposition ciclopirox from a topical antifungal agent to a promising virulence-modifying agent agent against P. aeruginosa, a problematic Gram-negative pathogen.
Analgesic and antipyretic actions of Muntingia calabura leaves chloroform extract in animal models
Zakaria, ZA,Kumar, G Hanan,Zaid, Siti NH Mohd,Ghani, Marwiza A,Hassan, MH,Hazalin, Nurul AMN,Khamis, Mahirah M,Devi, G Rathna,Sulaiman, MR Kyung Hee Oriental Medicine Research Center 2007 Oriental pharmacy and experimental medicine Vol.7 No.1
The present study was carried out to elucidate the potential of Muntingia (M.) calabura leaves chloroform extract (MCCE) as antinociceptive, anti-inflammatory and antipyretic agents using various animal models. The dried powdered leaves of M. calabura (20 g) were soaked in chloroform for 72 h and the supernatant obtained was then evaporated to dryness. The crude dried extract (0.912 g), dissolved in dimethyl sulfoxide (1:20; w/v) and considered as a stock solution (100% concentration/strength), was then diluted to the concentrations of 10 and 50% and used together in all experimental models. The MCCE was found to show significant (P < 0.05) antinociceptive and antipyretic activities, but less remarkable anti-inflammatory activity. Only the antinociceptive activity of MCCE measured using the abdominal constriction test and in the first phase of the formalin test occurred in a concentration-dependent manner. The anti-inflammatory activity of 50 and 100% concentrations MCCE was observed only at the range of time interval of 60 - 120 and 60 min, respectively. Based on the results, we conclude that the M. calabura leaves chloroform extract possessed remarkable antinociceptive and antipyretic, but less effective anti-inflammatory, activities and thus justifies the Peruvian folklore claims of its medicinal values.
Zakaria Boulghasoul,Zineb Kandoussi,Abdelhadi Elbacha,Abdelouahed Tajer 대한전기학회 2020 Journal of Electrical Engineering & Technology Vol.15 No.5
In this paper we present a new improved sensorless vector control of induction motor based on an improved adaptive Luenberger observer. The proposed observer is designed to estimate both speed and motor parameters from measured stator currents, stator voltages and estimated rotor fl uxes. The proposed sensorless drive has for purpose to compensate at the same time both stator resistance and rotor time constant inverse variation, which change during operation. Indeed, in the proposed adaptive Luenberger observer, a Fuzzy Logic Controller will be adopted as an adaptation mechanism. The proposed observer stability is proved by the Lyapunov’s theorem and its feasibility is verifi ed by series of experimental tests. The relevant results and the eff ectiveness of the improved system are clearly shown through obtained experimental results with an induction motor of 1 kW driven by dSPACE system.
Laryngeal Compensation for Voice Production After CO2 Laser Cordectomy
Zakaria Soliman,Sameh Mohammad Hosny,Mohammad Waheed El-Anwar,Amal Saeed Quriba 대한이비인후과학회 2015 Clinical and Experimental Otorhinolaryngology Vol.8 No.4
Objectives. Carbon dioxide (CO2) laser cordectomy is considered one of the modalities of choice for treatment of early glottic carcinoma. In addition to its comparable oncological results with radiotherapy and open surgical procedures, it preserves of laryngeal functions including voice production. The aim of this study was to detect how the larynx compensates for voice production after different types of CO2 laser cordectomy for early glottic carcinoma together with assessment of the vocal outcome in each compensation mechanism. Methods. One hundred twelve patients treated with CO2 laser cordectomy were classified according to their main postoperative phonatory site. Perceptual analysis of voice samples using GRBAS (grade, roughness, breathiness, asthenia, and strain) scale was done for 88 patients after exclusion of the voice samples of all female patients to make the study population homogenous and the samples of 18 male patients due to bad quality (4 patients) or unavailability (14 patients) of their voice samples and the results were compared with those obtained from control group that included 25 age-matched euphonic male subjects. Results. Five types of laryngeal compensation were defined including: vocal fold to vocal fold, vocal fold to vocal neofold, vocal fold to vestibular fold, vestibular fold, to vestibular fold, and arytenoids hyper adduction. Characters changes of voice produced by each compensation type were found to be statistically significant except for breathiness, asthenia and strain changes in vocal fold to vocal fold compensation type. Conclusion. The larynx can compensate for voice production after CO2 laser cordectomy by five different compensation mechanisms with none of them producing voice quality comparable with that of controls.