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DNA methylation involved in environmental adaptation of birch
Jiang Wang,Bowei Chen,Xu Zhang,Yu Wang,Yuhua Li,Qingzhu Zhang 강원대학교 산림과학연구소 2019 강원대학교 산림과학연구소 학술대회 Vol.2019 No.09
The boreal forest, with large tracts of unmanaged forests and low human impacts, is critical for the stability of global ecosystems. However, the boreal regions are subject to extensive ecosystem shifting, thinning and even loss under the climate changes and human activities, especially with the increasing of global warming. How to cope with the trend is extremely urgent. To illustrate responds of future populations of forest trees to climate change, it is essential to uncover past and present signatures of molecular adaptation in their genomes. Ecological epigenetics, as an interdisciplinary mainly answering how species, especially perennial, adapt to environmental changes epigenetically, is an important approach to detect the epigenetic mechanisms of boreal forest plants adapting to climate changes. Here, we will report the recent results about DNA methylation involved in environmental adaptation of birch, the pioneered trees of boreal forest.
Xiaozhen Zhang,Yuhua Jiang,Xuebing Hu,Liangliang Sun,Yihan Ling 대한금속·재료학회 2018 ELECTRONIC MATERIALS LETTERS Vol.14 No.2
Proton-conducting solid oxide fuel cell (H-SOFC) based on layered perovskite type GdBaCuCoO5+x (GBCC) cathodewas fabricated with in situ drop-coating BaZr0.1Ce0.7Y0.2O3−δ (BZCY) electrolyte membrane. The influences of Cu dopinginto Co sites of GdBaCo2O5+x on the electrical conductivity and conduction mechanism, thermal expansion propertyand electrochemical performance of cathode materials and corresponding single cell were investigated. Results show thatthe electrical conductivity decreased and the conduction mechanism would gradually transform to the semiconductor-likebehavior. A high maximum power density of 480 mW cm−2 was obtained for the anode supported NiO–BZCY/NiO–BZCY/BZCY/GBCC single cells with wet H2fuel at 700 °C. The corresponding polarization resistance was as low as 0.17 Ω cm2. The excellent electrochemical performance of as-prepared single cell indicates that GBCC is a good candidate of cathodematerials for H-SOFCs.
Bassiouny Saleh,Jinghua Jiang,Qiong Xu,Reham Fathi,Aibin Ma,Yuhua Li,Lisha Wang 대한금속·재료학회 2021 METALS AND MATERIALS International Vol.27 No.8
The main objective of this paper is to study the influence of wear testing parameters on the weight loss of AZ91 magnesiumalloy which was developed via rotary die-equal channel angular pressing (RD-ECAP) method through the different numberof passes. The AZ91 sample was pressed up to 16 passes in order to decrease the grain size to 10 μm. After RD-ECAP processing,significant grain refinement was found, which yielded a refined grain size after 16 passes and enhanced mechanicalproperties and wear resistance. Dry sliding wear experiments with a ball on disc apparatus at room temperature were conducted,following RD-ECAP processing. The response surface methodology (RSM) was used to optimize and compare thewear resistance of the RD-ECAP alloy and the as-received alloy. Analysis of the wear mechanism and the worn surfaces ofAZ91 samples was performed using scanning electron microscope. RSM analysis showed that increased applied load, slidingspeed and sliding time in all cases decreased wear resistance. On the other side, wear resistance in AZ91 magnesium alloywas improved by the increase in the number of passes of RD-ECAP. The three empirical models were validated by conductingconfirmation tests and certified that the proven empirical wear models are reliable for wear applications as a predictive tool.
Beneficial Effects of Resveratrol on Atherosclerosis
Enguo Fan,Lijuan Zhang,Sha Jiang,Yuhua Bai 한국식품영양과학회 2008 Journal of medicinal food Vol.11 No.4
Atherosclerosis, a progressive disease characterized by the accumulation of lipids and fibrous elements in the arteries, is a most important contributor to cardiovascular diseases. Resveratrol is a naturally occurring phytopolyphenol compound and shows the ability to reduce the risk of cardiovascular diseases. In this review, beneficial effects of resveratrol on the initiation and progression of atherosclerosis, including regulation of vasodilator and vasoconstrictor production, inhibition of oxidative stress/reactive oxygen species generation, anti-inflammation, inhibition of modification of low-density lipoproteins, anti-platelet aggregation, and its abilities to impede progression and modulate complications of atherosclerosis, are discussed.
Shuang Li,Bo Wang,Shun Jiang,Xiaohui Lan,Yongbo Qiao,Jiaojiao Nie,Yuhe Yin,Yuhua Shi,Wei Kong,Yaming Shan 대한수의학회 2021 Journal of Veterinary Science Vol.22 No.1
Background: Porcine circovirus type 2 (PCV2) is an important infectious pathogen implicated in porcine circovirus-associated diseases (PCVAD), which has caused significant economic losses in the pig industry worldwide. Objectives: A suitable viral vector-mediated gene transfer platform for the expression of the capsid protein (Cap) is an attractive strategy. Methods: In the present study, a recombinant adeno-associated virus 8 (rAAV8) vector was constructed to encode Cap (Cap-rAAV) in vitro and in vivo after gene transfer. Results: The obtained results showed that Cap could be expressed in HEK293T cells and BABL/c mice. The results of lymphocytes proliferative, as well as immunoglobulin G (IgG) 2a and interferon-γ showed strong cellular immune responses induced by Cap-rAAV. The enzyme-linked immunosorbent assay titers obtained and the IgG1 and interleukin-4 levels showed that humoral immune responses were also induced by Cap-rAAV. Altogether, these results demonstrated that the rAAV8 vaccine Cap-rAAV can induce strong cellular and humoral immune responses, indicating a potential rAAV8 vaccine against PCV2. Conclusions: The injection of rAAV8 encoding PCV2 Cap genes into muscle tissue can ensure long-term, continuous, and systemic expression.