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RISS 인기검색어
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- 저자 : Yonghui Zhou (검색결과 6 건)
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Yonghui Zhou,Hu Sun,Anhai Li,Minghang Lv,Chaoyi Xue,Jun Zhao 대한기계학회 2019 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.33 No.7
The Johnson-Cook (JC) constitutive model was utilized to simulate the processing of Al-Si piston alloy ZL109 to obtain the optimal finishing parameters in polycrystalline diamond (PCD) tool, and studied the machining quality of ordinary-turning under the optimized cutting parameters. PCD is brittle, so it is difficult to manufacture orthogonal blades and is easy to break and high cost. We have adopted ordinary-turning quality to verify simulation results. Effect of cutting parameters on residual stress, cutting force and temperature was investigated through simulation, meanwhile, effect of cutting parameters on surface roughness and residual stress was analyzed by experiments. It indicates the verification method is practicable, and residual stress, cutting force and temperature are the smallest in simulation, and the experimental values of surface roughness and residual stress are also the smallest under the optimal cutting parameters, which can guide the cutting parameters selection to obtain higher machining quality.
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Lei Zhou,Lin Fu,Na Lv,Jing Liu,Yan Li,Xiaosu Chen,Qingyu Xu,Guofeng Chen,Baoxu Pang,Lili Wang,Yonghui Li,Xiaodong Zhang,Li Yu 생화학분자생물학회 2018 Experimental and molecular medicine Vol.50 No.-
The AML1-ETO fusion protein (A/E), which results from the t(8;21) translocation, is considered to be a leukemiainitiating event. Identifying the mechanisms underlying the oncogenic activity of A/E remains a major challenge. In this study, we identified a specific down-regulation of brain acid-soluble protein 1 (BASP1) in t(8;21) acute myeloid leukemia (AML). A/E recognized AML1-binding sites and recruited DNA methyltransferase 3a (DNMT3a) to the BASP1 promoter sequence, which triggered DNA methylation-mediated silencing of BASP1. Ectopic expression of BASP1 inhibited proliferation and the colony-forming ability of A/E-positive AML cell lines and led to apoptosis and cell cycle arrest. The DNMT inhibitor decitabine up-regulated the expression of BASP1 in A/E-positive AML cell lines. In conclusion, our data suggest that BASP1 silencing via promoter methylation may be involved in A/E-mediated leukemogenesis and that BASP1 targeting may be an actionable therapeutic strategy in t(8;21) AML.
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Common Correlated Effects Estimation of Unbalanced Panel Data Models with Cross-Sectional Dependence
Qiankun Zhou,Yonghui Zhang 한국계량경제학회 2016 계량경제학보 Vol.27 No.4
We consider the estimation and inference of unbalanced panel data models with cross-sectional dependence with a large number of individual units in a relatively short time period. By following the common correlated effects (CCE) approach of Pesaran (2006), we propose a CCE estimator for unbalanced panels (CCE-UB). The asymptotics of the CCE-UB estimator is developed in the paper. Small scale Monte Carlo simulation is conducted to examine the finite sample properties of the proposed estimator.
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Ge, Xiaogai,Zhou, Benzhi,Wang, Xiaoming,Li, Qian,Cao, Yonghui,Gu, Lianhong Springer Japan 2018 Ecological research Vol.33 No.2
<P><B>Abstract</B></P><P>Drought can severely affect carbon dynamics in forest ecosystems through impacts on carbon storage, reduced carbon fixation, abatement of the carbon sink function, and alteration of carbon sink‐source relationships. Currently, little is known about the effects of drought on the productivity and spatial patterns of carbon in bamboo forests. The objective of this study was to assess the effect of imposed drought on the carbon storage and soil carbon dynamics of a bamboo forest ecosystem in subtropical area of China. Drought was imposed via throughfall exclusion in moso bamboo forest from July 2012 to April 2013. Results indicated that bamboo shoots, new culms, shoot height, and diameter at breast height were significantly lower in throughfall exclusion (TE) plots than in control check (CK) plots, with decrease of 64.6, 70.8, 10.6 and 11.3%, respectively. Annual carbon sequestration for TE plots was 58.1% lower than that for CK plots. Soil carbon storage in the 0–60‐cm layer in CK and TE plots decreased by 3.7 and 12.2%, respectively, indicating that drought can decrease soil respiration by altering substrate availability. Ecosystem carbon storage increased by 4.75 t ha<SUP>−1</SUP> in CK plots but decreased by 13.71 t ha<SUP>−1</SUP> in TE plots. Our findings highlight that drought can reduce carbon storage and alter the spatial pattern of carbon in moso bamboo forest ecosystems, particularly when drought occurs during the development bamboo shoot. Our findings should provide a better understanding of carbon sequestration potential and aid determination of how future climate change may impact carbon budgets.</P>
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Impact response of a novel flat steel-concrete-corrugated steel panel
Jingyi Lu,Yonghui Wang,Ximei Zhai,Hongyuan Zhou 국제구조공학회 2022 Steel and Composite Structures, An International J Vol.42 No.2
A novel flat steel plate-concrete-corrugated steel plate (FS-C-CS) sandwich panel was proposed for resisting impact load. The failure mode, impact force and displacement response of the FS-C-CS panel under impact loading were studied via drop-weight impact tests. The combined global flexure and local indentation deformation mode of the FS-C-CS panel was observed, and three stages of impact process were identified. Moreover, the effects of corrugated plate height and steel plate thickness on the impact responses of the FS-C-CS panels were quantitatively analysed, and the impact resistant performance of the FS-C-CS panel was found to be generally improved on increasing corrugated plate height and thickness in terms of smaller deformation as well as larger impact force and post-peak mean force. The Finite Element (FE) model of the FS-C-CS panel under impact loading was established to predict its dynamic response and further reveal its failure mode and impact energy dissipation mechanism. The numerical results indicated that the concrete core and corrugated steel plate dissipated the majority of impact energy. In addition, employing end plates and high strength bolts as shear connectors could prevent the slip between steel plates and concrete core and assure the full composite action of the FS-C-CS panel.
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Failure Mechanisms of Graded Ceramic Tool in Ultra High Speed Dry Milling of Inconel 718
Guangming Zheng,Jun Zhao,Anhai Li,Xiaobin Cui,Yonghui Zhou 한국정밀공학회 2013 International Journal of Precision Engineering and Vol. No.
A graded ceramic tool material was fabricated by hot-pressing. Its cutting performance and failure mechanisms were investigated in dry face milling of Inconel 718 using round inserts at ultra high speeds ranging from 500 to 1600 m/min. The results showed that the microscopic chip shape was serrated type and the minimal cutting force was obtained at 900 m/min under this ultra high speed cutting conditions. Due to the enhanced mechanical properties and higher fracture resistance, the graded tool showed a selfsharpening characteristic. And the notch wear resistance of the graded tool was higher than that of the common reference tool under the same cutting condition. The failure mechanisms involved chipping, flaking, abrasive wear and adhesive wear. The mechanisms responsible for the higher cutting performance of the graded tool were determined to be the higher mechanical properties. The understanding of the failure mechanisms in ultra high speed milling processes can provide the guidance for the proper application of the tools, furthermore the guidance for tool materials design.
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