Application of METSIM in Process Design of the Cleaner Chromate Production Using Sub-molten Salt

Ye-qing LV,Shi-li Zheng,Shao-na Wang,Hao Du,Yi Zhang 보안공학연구지원센터 2013 International Journal of Bio-Science and Bio-Techn Vol.5 No.2

Positive Association of Human SHC3 Gene with Schizophrenia in a Northeast Chinese Han Population

Ye Lv,Yang Sun,Guan-Yu Wang,Jian Yin,Cheng-Jie Li,Yi-Yang Luo,Zhi-Lin Luan 대한신경정신의학회 2020 PSYCHIATRY INVESTIGATION Vol.17 No.9

Objective Schizophrenia is one of the most devastating neuropsychiatric disorders. Genetic epidemiological studies have confirmed that schizophrenia is a genetic disease. Genes promoting neurodevelopment may be potential candidates for schizophrenia. As an adaptor linking a number of tyrosine kinase receptors in multiple intracellular signaling cascades, Src homology 2 domain containing transforming protein 3 (SHC3) is a member of the Shc-like adaptor protein family, and expressed predominantly in the mature neurons of the central nervous system (CNS). In the present study, we aimed to investigate the association of SHC3 and schizophrenia. Methods An independent case-control association study was performed in a sample including 710 schizophrenia patients and 1314 healthy controls from a Northeast Chinese Han population. Results The allelic and genotypic association analyses showed that four SNPs in SHC3 significantly associated with schizophrenia(rs2316280, rs4877041, rs944485 and rs7021743). The haplotype composing of these four SNPs also showed significantly individual and global association with schizophrenia. Conclusion Our present results suggest SHC3 as a susceptibility gene for schizophrenia.

Ethylene Control of Flowering and Sex Differentiation in Three Sex Types of Inbred Melon Lines

Hongxia Ye,Tonglin Wang,Lv Lv,Yuqing Hu,Bingliang Wang 한국원예학회 2020 원예과학기술지 Vol.38 No.4

Flower types and sex expression are important traits for melon (Cucumis melo L.) and hybrid seed production. Here, we studied the effects of ethrel, aminoethoxyvinylglycine (AVG) and silver nitrate (AgNO3) on floral development and sex expression in andromonoecious, monoecious, and hermaphroditic inbred melon lines in an experimental field at Zhejiang University, Hangzhou China during the autumn of 2017. The application of 100, 200, and 400 µL·L-1 of 40% ethrel delayed the initiation of male/bisexual flowers on the main stem and inhibited the formation of lateral branches bearing female/bisexual flowers. Ethrel exposure changed the flower sex type on the main stem of the three inbred melon lines. Melon sexual types could be converted from andromonoecious to hermaphroditic, from monoecious to gynoecious, and from hermaphroditic to gynomonoecious/gynoecious and be devoid of buds destined to be male flowers. The three inbred melon lines responded differently to ethrel during floral development and sex transition, with the monoecious line being the most sensitive and the hermaphroditic line being the most insensitive. The inhibitor of ethylene biosynthesis, AVG (100 mg·L-1), and the inhibitor of ethylene action, AgNO3 (300 mg·L-1), were ineffective in altering sex expression. However, the male/bisexual flowers on the main stem formed at lower nodes in AVG- or AgNO3-treated plants, resulting in earlier flower initiation for the hermaphroditic line. Thus, the application of AVG or AgNO3 promoted earlier fruit setting in hermaphroditic melon. In addition, the use of ethrel to induce male sterility in melon could replace the expensive labor necessary for the mechanical emasculation of hybrids and ensure hybrid seed purity.

3’’-Hydroxyamentoflavone and Its 7-O-Methyl Ether, Two New Biflavonoids fromAristolochia contorta

Ye-Gao Chen,Li-Li Yu,Rong Huang,Jia-Chuan Liu,Yu-Ping Lv,Yong Zhao 대한약학회 2005 Archives of Pharmacal Research Vol.28 No.11

Two new biflavonoids, 3’’-hydroxyamentoflavone-7-O-methyl ether (1) and 3’’-hydroxyamentoflavone (2), were isolated from the fruits of Aristolochia contorta Bge. Their structures were elucidated by HR-ESI-MS, 1D-, and 2D-NMR spectroscopy.

11-Methoxyviburtinal, A New Iridoid from Valeriana jatamansi

Ye-Gao Chen,Li-Li Yu,Rong Huang,Yu-Ping Lv,Shi-Hong Gui 대한약학회 2005 Archives of Pharmacal Research Vol.28 No.10

Five compounds of iridoids, lignan and phenylpropanoid glycosides were isolated from the roots of Valeriana jatamansi by column chromatography. Their structures were elucidated as 11-methoxyviburtinal (1), baldrinal (2), prinsepiol-4-O-β-D-glucoside (3), coniferin (4), and hexacosanic acid (5) by spectroscopic analysis. 11- Methoxyviburtinal was a new compound, and others were isolated from the plant for the first time.

<i>Salmonella enterica</i> Serovar Typhimurium Interacts with CD209 Receptors To Promote Host Dissemination and Infection

Ye, Chenglin,Li, Qiao,Li, Xinyi,Park, Chae Gyu,He, Yingxia,Zhang, Yingmiao,Wu, Bicong,Xue, Ying,Yang, Kun,Lv, Yin,Ying, Xiao-Ling,Ding, Hong-Hui,Cai, Huahua,Alkraiem, Ayman Ahmad,Njiri, Olivia,Tembo, American Society for Microbiology 2019 Infection and immunity Vol.87 No.8

<P><I>Salmonella enterica</I> serovar Typhimurium, a Gram-negative bacterium, can cause infectious diseases ranging from gastroenteritis to systemic dissemination and infection. However, the molecular mechanisms underlying this bacterial dissemination have yet to be elucidated. A study indicated that using the lipopolysaccharide (LPS) core as a ligand, <I>S</I>.</P><P><I>Salmonella enterica</I> serovar Typhimurium, a Gram-negative bacterium, can cause infectious diseases ranging from gastroenteritis to systemic dissemination and infection. However, the molecular mechanisms underlying this bacterial dissemination have yet to be elucidated. A study indicated that using the lipopolysaccharide (LPS) core as a ligand, <I>S</I>. Typhimurium was able to bind human dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin (hCD209a), an HIV receptor that promotes viral dissemination by hijacking antigen-presenting cells (APCs). In this study, we showed that <I>S</I>. Typhimurium interacted with CD209s, leading to the invasion of APCs and potentially the dissemination to regional lymph nodes, spleen, and liver in mice. Shielding of the exposed LPS core through the expression of O-antigen reduces dissemination and infection. Thus, we propose that similar to HIV, <I>S</I>. Typhimurium may also utilize APCs via interactions with CD209s as a way to disseminate to the lymph nodes, spleen, and liver to initiate host infection.</P>

An Adaptable University Human Resource Data Management

Ye Fan,Shaoyun Guan,Honglue LV 보안공학연구지원센터 2015 International Journal of Database Theory and Appli Vol.8 No.1

Data management is the foundation of the University Human Resource Management Systems (UHRMSs). The data collected by the different departments in university human resource systems is distortion, logical confusion and unstructured. In order to overcome these defects, we design an adaptable university human resource management system. In the system, the technology of adaptive computing is adopted to enhance the self-management capability of UHRMS and decrease the complexity of management. Experimental results show that the proposed adaptable UHRMS has a lower transaction response time and a higher throughput than the traditional methods.

Triterpenoids from Schisandra henryi with Cytotoxic Effect on Leukemia and Hela Cells In Vitro

Chen, Ye-Gao,Wu, Zheng-Cai,Lv, Yu-Ping,Gui, Shi-Hong,Wen, Jin,Liao, Xin-Rong,Yuan, Li-Ming,Halaweish, Fathi The Pharmaceutical Society of Korea 2003 Archives of Pharmacal Research Vol.26 No.11

Four known lanostane triterpenoids, schiprolactone A (1), schisanlactone B (2), nigranoic acid (3) and schisandronic acid (4) Were isolated from the stems of Schisandra henryi for the first time. Their structures were characterized by IR, MS and NMR techniques. Compounds 1, 2 and 4 showed moderate cytotoxic activity against Leukemia cells in vitro. Cytotoxic activity of compounds 1-4 showed $IC_{50}$ of 0.0097, 0.01, 0.097 and 0.0099 $\mu$ mol/mL respectively toward Leukemia cells and $IC_{50}$ of 0.097, 0.1, 0.097 and 0.099 $\mu$mol/mL toward Hela cells respectively. It is the first report that these compounds possess cytotoxic activity on Leukemia and Hela cells.

3'-Hydroxyamentoflavone and Its 7-O-Methyl Ether, Two New Biflavonoids from Aristolochia contorta

Chen Ye-Gao,Yu Li-Li,Huang Rang,Liu Jia-Chuan,Lv Yu-Ping,Zhao Yang The Pharmaceutical Society of Korea 2005 Archives of Pharmacal Research Vol.28 No.11

Two new biflavonoids, 3'-hydroxyamentoflavone-7-O-methyl ether (1) and 3'-hydroxyamentoflavone (2), were isolated from the fruits of Aristolochia contorta Bge. Their structures were elucidated by HR-ESI-MS, 1D-, and 2D-NMR spectroscopy.

Pelagic larval dispersal habits influence the population genetic structure of clam Gomphina aequilatera in China

Yingying Ye,Zeqin Fu,Yunfang Tian,Jiji Li,Baoying Guo,Zhenming Lv,Changwen Wu 한국유전학회 2018 Genes & Genomics Vol.40 No.11

Pelagic larval dispersal habits influence the population genetic structure of marine mollusk organisms via gene flow. The genetic information of the clam Gomphina aequilatera (short larval stage, 10 days) which is ecologically and economically important in the China coast is unknown. To determine the influence of planktonic larval duration on the genetic structure of G. aequilatera. Mitochondrial markers, cytochrome oxidase subunit i (COI) and 12S ribosomal RNA (12S rRNA), were used to investigate the population structure of wild G. aequilatera specimens from four China Sea coastal locations (Zhoushan, Nanji Island, Zhangpu and Beihai). Partial COI (685 bp) and 12S rRNA (350 bp) sequences were determined. High level and significant FST values were obtained among the different localities, based on either COI (FST = 0.100–0.444, P < 0.05) or 12S rRNA (FST = 0.193–0.742, P < 0.05), indicating a high degree of genetic differentiation among the populations. The pairwise Nm between Beihai and Zhoushan for COI was 0.626 and the other four pairwise Nm values were > 1, indicating extensive gene flow among them. The 12S rRNA showed the same pattern. AMOVA test results for COI and 12S rRNA indicated major genetic variation within the populations: 77.96% within and 22.04% among the populations for COI, 55.73% within and 44.27% among the populations for 12S rRNA. A median-joining network suggested obvious genetic differentiation between the Zhoushan and Beihai populations. This study revealed the extant population genetic structure of G. aequilatera and showed a strong population structure in a species with a short planktonic larval stage.